CSIMarket
 

Protagonist Therapeutics inc   (NASDAQ: PTGX)

Protagonist Therapeutics Inc 's

Competitiveness




 

PTGX Sales vs. its Competitors Q2 2026



Comparing the current results to its competitors, Protagonist Therapeutics Inc reported Revenue increase in the 2 quarter 2026 by 3749.17 % year on year.
The sales growth was above Protagonist Therapeutics Inc 's competitors' average revenue growth of 12.04 %, achieved in the same quarter.

List of PTGX Competitors

With a net margin of 76.28 % Protagonist Therapeutics Inc achieved higher profitability than its competitors.

More on PTGX Profitability Comparisons



Revenue Growth Comparisons




Net Income Comparison


Protagonist Therapeutics inc achieved net profit of $162.85 millions compared to a net loss of $-34.77 millions recorded in the same quarter a year ago.

<<  PTGX Stock Performance Comparisons


Protagonist Therapeutics Inc 's Comment on Competition and Industry Peers


The competitive landscape includes emerging oral macrocyclic peptides such as PeptiDream’s dual IL-17A/IL-17F candidate. In the treatment of polycythemia vera (PV), competitors include Ruxolitinib (Jakafi®) marketed by Incyte, Besremi® (ropeginterferon alfa-2b-nicotinamide) by PharmaEssentia/AOP, bomedemstat by Merck/Imago, and givinostat by Italfarmaco. Additional competition arises from RNA-based therapies such as divesiran by Silence Therapeutics and DISC-3405 by Disc Medicine, as well as investigational therapies from Alnylam Pharmaceuticals and vamifeport by CSL Vifor. In obesity and weight management, competition is led by glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonists, including approved injectable therapies Wegovy® (semaglutide) by Novo Nordisk and Zepbound® (tirzepatide) by Eli Lilly. The FDA approved oral Wegovy® by Novo Nordisk in December 2025. The landscape also includes multi-receptor agonists such as Retatrutide by Eli Lilly, CagriSema (a combination of semaglutide and cagrilintide) by Novo Nordisk, and MariTide (maridebart cafraglutide) by Amgen. Competitors named across filings include Alnylam Pharmaceuticals, Amgen, CSL Vifor, Disc Medicine, Eli Lilly, Incyte, Italfarmaco, Merck/Imago, Novo Nordisk, PeptiDream, PharmaEssentia/AOP, and Silence Therapeutics.



  

Overall company Market Share Q2 2026

Due to outstanding performance in Overall company, revenue grew by 3749.17 % Protagonist Therapeutics inc improved its market share, to approximately 0.15 %.




<<  More on PTGX Market Share.
 
*Market share is calculated based on total revenue.





Publicly Traded Peers of Protagonist Therapeutics inc




Verastem Inc
Share Performance



-7.68%
Over The Past 5 Days



Verastem Inc
Profile

Verastem Inc is a biopharmaceutical company that focuses on discovering and developing medicines to treat cancer by targeting the underlying biology of the disease. They employ a research-driven business model to identify novel therapeutic candidates, evaluate their potential through preclinical and clinical trials, and bring them to market with the goal of improving patient outcomes. Verastem emphasizes innovation, precision medicine, and strategic collaborations to advance their pipeline of cancer therapeutics.

More about Verastem Inc 's Market Share

Market Cap. Revenues TTM Net Income TTM
$ 733.850 mill. $ 87.526 mill. $ -202.698 mill.


Bristol myers Squibb Company
Share Performance



+19.98%
This Year



Bristol myers Squibb Company
Profile

Bristol Myers Squibb Company operates a research and development-driven business model, focusing on the discovery and delivery of innovative medicines for various diseases. It emphasizes collaboration with academic institutions, government entities, and other pharmaceutical firms to enhance its therapeutic portfolio and improve patient outcomes.

More about Bristol myers Squibb Company's Market Share

Market Cap. Revenues TTM Net Income TTM
$ 131,358.720 mill. $ 49,186.000 mill. $ 9,274.000 mill.


Casi Pharmaceuticals inc
Share Performance



-8.00%
This Quarter



Casi Pharmaceuticals inc
Profile

CASI Pharmaceuticals, Inc. and its subsidiaries operate in pharmaceutical development and manufacturing.

More about Casi Pharmaceuticals inc 's Market Share

Market Cap. Revenues TTM Net Income TTM
$ 2.388 mill. $ 20.712 mill. $ -48.058 mill.


Cns Pharmaceuticals Inc
Share Performance



+7.55%
This Year



Cns Pharmaceuticals Inc
Profile

CNS Pharmaceuticals Inc's business model focuses on developing innovative solutions and treatments for central nervous system diseases.

More about Cns Pharmaceuticals Inc 's Market Share

Market Cap. Revenues TTM Net Income TTM
$ 38.978 mill. $ - mill. $ -16.699 mill.


Cadrenal Therapeutics Inc
Share Performance



-73.95%
This Quarter



Cadrenal Therapeutics Inc
Profile

Cadrenal Therapeutics Inc's business model revolves around the development and commercialization of innovative therapies in the field of renal diseases.

More about Cadrenal Therapeutics Inc's Market Share

Market Cap. Revenues TTM Net Income TTM
$ 3.059 mill. $ - mill. $ -12.715 mill.

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Sources: Protagonist Therapeutics inc’s official press releases and regulatory filings; CSIMarket.com’s market research; and the financial filings and press releases of other companies cited in this report.
Updated on:
Focus of this report: publicly traded companies.
For your research, we’ve provided 10 tables on Protagonist Therapeutics inc versus competitors, including market share analysis.
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