Pliant Therapeutics Inc's Competitiveness
A competitive positioning analysis and financial ratio benchmarking of Pliant Therapeutics Inc (PLRX) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.
Key Findings: Pliant Therapeutics Inc vs Its Competitors
- TTM: Trailing 12-month revenue of 10M vs 147,294M combined for tracked competitors (0.0% combined share).
- Scale: Pliant Therapeutics Inc ranks #319 of 544 companies by market capitalization in the Major Pharmaceutical Preparations industry, holding 0.0% of industry market cap.
- Peer differentiation: Revenue per employee of $0.20M compares with $1.06M for the peer group (0.2x).
Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).
Pliant Therapeutics Inc vs. its Competitors, Q2 2026
TTM net margin
TTM = trailing twelve months. Run-rate annualizes the latest quarter (×4) and compares it to TTM. In millions of $. High-Confidence Competitors are named as a competitor directly in an SEC filing; Similar-Size Competitors are the closest peers by market-cap rank within the same industry; Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC, all independent of the competitor list.
TTM revenue, latest-quarter run-rate and net income/margin benchmarked across Pliant Therapeutics Inc and its 4 competitor groupings. Available under Commercial License.
| Entity | TTM Revenue | Rev Run-rate vs TTM |
|---|---|---|
| Pliant Therapeutics Inc | $12,345M | +12.3% · Accelerating |
| Competitors combined | $12,345M | +12.3% · Accelerating |
| High-Confidence Competitors (11) | $12,345M | +12.3% · Accelerating |
| Similar-Size Competitors (9) | $12,345M | +12.3% · Accelerating |
TTM revenue, run-rate and net margin benchmarking across Pliant Therapeutics Inc's competitor groups requires a Commercial License.
Pliant Therapeutics Inc's Competitor Quality Breadth
Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).
| Entity | Profitable | Expanding | Above Industry Growth | Distressed |
|---|---|---|---|---|
| Pliant Therapeutics Inc | - | - | - | No |
| Competitors combined (125) | ||||
| High-Confidence Competitors (18) | ||||
| Similar-Size Competitors (10) |
Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.
PLRX Stock Performance relative to its Competitors
PLRX Stock Performance relative to High-Confidence Competitors
PLRX Stock Performance relative to Similar-Size Competitors
5 Best-Performing Tracked Competitors, Trailing 12 Months
| # | Competitor | TTM Share Price Return | vs U.S.A. 500 |
|---|---|---|---|
| 1 | Gt Biopharma Inc | 282.9% | Outperformed |
| 2 | Adlai Nortye Ltd | 282.9% | Outperformed |
| 3 | Erasca Inc | 282.9% | Outperformed |
| 4 | Sellas Life Sciences Group Inc | 282.9% | Outperformed |
| 5 | Spruce Biosciences Inc | 282.9% | Outperformed |
TTM share price return and U.S.A. 500 outperformance for Pliant Therapeutics Inc's best-performing tracked competitors requires a Commercial License.
Source: CSIMarket API, trailing 12 months.
Pliant Therapeutics Inc's Comment on Competition and Industry Peers
Publicly Traded Peers of Pliant Therapeutics Inc
Revenue and income for trailing 12 months, in millions of $, except employees| Company | Market Cap | Revenues |
|---|---|---|
| Pliant Therapeutics Inc | 66.87 | 9.85 |
| Abbvie Inc | 471,581.88 | 64,386.00 |
| Astrazeneca Plc | 259,526.30 | 58,739.00 |
| Vertex Pharmaceuticals Inc | 134,661.38 | 12,587.20 |
| Bristol myers Squibb Company | 130,826.24 | 49,186.00 |
| Regeneron Pharmaceuticals Inc | 79,738.50 | 15,534.70 |
| SUBTOTAL | 1,250,945.43 | 213,927.53 |
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Sources: Pliant Therapeutics Inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Pliant Therapeutics Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.
Pliant Therapeutics Inc's Competitors Named by the Company
Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.| Competitor | Basis | Confidence |
|---|---|---|
| Ngm Biopharmaceuticals Inc | Named by the company | 85% |
| AbbVie Inc. | Named by the company | 85% |
| Boehringer Ingelheim Pharmaceuticals | Named by the company | 85% |
| Galapagos | Named by the company | 85% |
| Liminal BioSciences, Inc. | Named by the company | 85% |
| Vicore Pharma Holding | Named by the company | 85% |
| Corbus Pharmaceuticals Holdings Inc | Named by the company | 85% |
| Biomx Inc | Named by the company | 85% |
| Biogen, Inc. | Named by the company | 85% |
| Endeavor Biomedicines | Named by the company | 85% |
| iosciences | Named by the company | 85% |
| Teva Pharmaceutical Industries Ltd. | Named by the company | 85% |
| Mirum Pharmaceuticals Inc | Named by the company | 85% |
| Amgen Inc. | Named by the company | 85% |
| Bristol Myers Squibb Co. | Named by the company | 85% |
| Galecto Biotech, Inc. | Named by the company | 85% |
| Roche Holding AG | Named by the company | 85% |
| Damora Therapeutics Inc | Named by the company | 85% |
| PHGEU | Named by the company | 85% |
| Boehringer Ingelheim GmbH | Named by the company | 85% |
| FibroGen | Named by the company | 85% |
| Kadmon Holdings, Inc. | Named by the company | 85% |
| United Therapeutics Corporation | Named by the company | 85% |
| Chemomab Therapeutics Ltd | Named by the company | 85% |
| AstraZeneca plc | Named by the company | 85% |
| CSL Behr | Named by the company | 85% |
| Gilead Sciences | Named by the company | 85% |
| Sandoz Group AG | Named by the company | 85% |
| GLTO | Named by the company | 85% |
| Medicines Co | Named by the company | 85% |
Filing basis, confidence, active dates and source counts for Pliant Therapeutics Inc's named competitors require a Commercial License.
Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.
Pliant Therapeutics Inc's Business Segment Mix vs Peers
Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).| Company | Largest Segment |
|---|---|
| Vertex Pharmaceuticals Inc | Pharmaceuticals 100.00 % |
| Incyte Corporation | Reportable 100.00 % |
| Madrigal Pharmaceuticals Inc | Reportable 100.00 % |
| Protagonist Therapeutics inc | Single reportable segment 100.00 % |
| Blueprint Medicines Corporation | Single Reportable Segment 100.00 % |
Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).
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Pliant Therapeutics Inc's Productivity vs Peers Comparison
Revenue and income per employee, trailing 12 months, in $; market cap in millions of $| Company | Market Cap | Revenue / Employee | Income / Employee |
|---|---|---|---|
| Pliant Therapeutics Inc | 67 | 200,959 | -1,883,449 |
| Abbvie Inc | 471,582 | 1,129,579 | 110,807 |
| Astrazeneca Plc | 259,526 | 706,847 | 123,141 |
| Vertex Pharmaceuticals Inc | 134,661 | 31,079,506 | 10,877,037 |
| Bristol myers Squibb Company | 130,826 | 1,513,415 | 285,354 |
| Regeneron Pharmaceuticals Inc | 79,739 | 1,008,092 | 280,902 |
| PEERS TOTAL | 1,250,879 | 1,055,607 | 141,766 |
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Pliant Therapeutics Inc's Geographic Revenue Exposure vs Peers
Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.| Company | Largest Market |
|---|---|
| Vertex Pharmaceuticals Inc | United States 61.68 % |
| Bristol myers Squibb Company | United States 67.79 % |
| Incyte Corporation | United States 93.16 % |
| Xoma Royalty Corporation | CH 54.36 % |
| Adc Therapeutics Sa | United States 96.08 % |
Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.
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Pliant Therapeutics Inc's Position in Industry Market Structure
Market-capitalization share and concentration across all 498 companies in Pliant Therapeutics Inc's industry classification, broader than the peer set above. Market cap in millions of $.Pliant Therapeutics Inc ranks #319 of 498 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 827, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).
| Rank | Company | Market Cap | Industry Share |
|---|---|---|---|
| 1 | Eli Lilly And Company | 1,062,533 | 19.39 % |
| 2 | Johnson and Johnson | 664,610 | 12.13 % |
| 3 | Beone Medicines Ltd | 545,679 | 9.96 % |
| 4 | Abbvie Inc | 467,633 | 8.54 % |
| 5 | Merck and Co Inc | 1,234 | 5.2% |
| 6 | Novartis Ag | 1,234 | 5.2% |
| 7 | Abbott Laboratories | 1,234 | 5.2% |
| 8 | Novo Nordisk A | 1,234 | 5.2% |
| 9 | Pfizer Inc | 1,234 | 5.2% |
| 10 | Vertex Pharmaceuticals Inc | 1,234 | 5.2% |
| 319 | Pliant Therapeutics Inc | 67 | 0.00 % |
Market cap and industry share for the rest of Pliant Therapeutics Inc's industry peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-28.
Pliant Therapeutics Inc's Same-Size Peers & Stock Performance
Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.| Rank | Company | Market Cap | TTM Return |
|---|---|---|---|
| 314 | Pmv Pharmaceuticals Inc | 71 | -4.64 % |
| 315 | Fortress Biotech Inc | 71 | -40.43 % |
| 316 | Spero Therapeutics Inc | 69 | -38.40 % |
| 317 | Hyperion Defi inc | 68 | -52.60 % |
| 318 | Connect Biopharma Holdings Limited | 1,234 | 12.3% |
| 319 | Pliant Therapeutics Inc | 67 | -24.65 % |
| 320 | Skye Bioscience Inc | 1,234 | 12.3% |
| 321 | Xbiotech Inc | 1,234 | 12.3% |
| 322 | Cingulate Inc | 1,234 | 12.3% |
| 323 | Boundless Bio Inc | 1,234 | 12.3% |
| 324 | Veru Inc | 1,234 | 12.3% |
Market cap, return, momentum, beta and Sharpe ratio for the rest of Pliant Therapeutics Inc's same-size peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-09-28. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.
Pliant Therapeutics Inc's Valuation vs Competitive Position
Valuation multiples vs the Major Pharmaceutical Preparations industry average (341 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns.| Metric | Company | Industry Average | Difference |
|---|---|---|---|
| P/E | 0.3x | 25.1x | -24.8x |
| EV / EBITDA | - | 17.3x | - |
| P/B | 0.4x | 4.5x | -4.1x |
| Return on Equity | -53.22 % | industry aggregate | -70.47 % |
| Return on Invested Capital | -25.53 % | -2.95 % (avg) | -22.58 % |
Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.
Pliant Therapeutics Inc's Multi-Year Financial Trajectory
Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.| Metric | 2020 | 2021 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | - | - | - | - |
| Operating Margin | - | -1,288.10 % | - | - |
| Return on Invested Capital | - | -20.94 % | -28.60 % | -32.54 % |
| P/E | - | - | 3.8x | 0.6x |
Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.
Pliant Therapeutics Inc's BCG Growth-Share Matrix
Relative market share (vs Pliant Therapeutics Inc's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.
Pliant Therapeutics Inc falls in the Dog quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 8.0% (median, trailing 12 months).
Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.
Pliant Therapeutics Inc's Competitive Forces (Porter's Five Forces)
Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.| Force | Assessment | Basis |
|---|---|---|
| Competitive Rivalry | High | Industry HHI of 827 (see Industry Market Structure & Concentration above) |
| Supplier Power | Not covered on this page | See Pliant Therapeutics Inc's dedicated suppliers page for concentration and dependency data |
| Buyer Power | Not covered on this page | See Pliant Therapeutics Inc's dedicated customers page for concentration and dependency data |
| Threat of Substitutes | - | No systematic data source for cross-product substitution exists in this system; not estimated |
Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.
Pliant Therapeutics Inc's Industry Attractiveness & Competitive Strength
A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.
Pliant Therapeutics Inc falls in the Low attractiveness / Low strength cell: Harvest / Divest.
Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.
Pliant Therapeutics Inc's SWOT
Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.Strengths
No rule matched.
Weaknesses
- Return on equity 70.5 points below the industry aggregate.
- Underperforming the U.S.A. 500 over the trailing 12 months.
- Low relative market share vs the industry leader (0.00x).
Opportunities
- A meaningful share of tracked competitors (45.70 %) show financial-distress signals, a possible opening to gain share.
Threats
No rule matched.
Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.
Pliant Therapeutics Inc's Financial Strength vs Peers Comparison
Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months| Company | Quick Ratio | Working Capital | Debt / Equity |
|---|---|---|---|
| Pliant Therapeutics Inc | 3.06 | 12.82 | 0.04 |
| Abbvie Inc | 0.16 | 0.75 | - |
| Astrazeneca Plc | 0.19 | 0.94 | 0.51 |
| Vertex Pharmaceuticals Inc | 1.34 | 2.85 | - |
| Bristol myers Squibb Company | 0.49 | 1.35 | 2.31 |
| Regeneron Pharmaceuticals Inc | 0.57 | 3.74 | 0.06 |
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.
Pliant Therapeutics Inc's Revenue and Income Growth vs Peers
Quarterly revenue and net income growth, year over year and quarter over quarter| Company | Period | Revenue Y/Y | Income Y/Y |
|---|---|---|---|
| Pliant Therapeutics Inc | Q2 2026 | - | - |
| Abbvie Inc | Q2 2026 | +10.2 % | +284.3 % |
| Astrazeneca Plc | Q4 2025 | +8.6 % | +45.3 % |
| Vertex Pharmaceuticals Inc | Q2 2026 | +12.5 % | +6.5 % |
| Bristol myers Squibb Company | Q2 2026 | +5.7 % | +152.6 % |
| Regeneron Pharmaceuticals Inc | Q2 2026 | +16.7 % | -6.8 % |
| PEERS TOTAL | +10.8 % | +103.0 % |
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.
Pliant Therapeutics Inc's Peers' Costs of Sales and Capital Expenditures
Context for revenue growth: peer costs and capex, year over year and quarter over quarter| Company | Period | Costs Y/Y | Capex Y/Y |
|---|---|---|---|
| Pliant Therapeutics Inc | Q2 2026 | - | - |
| Abbvie Inc | Q2 2026 | -1.3 % | +19.7 % |
| Astrazeneca Plc | Q4 2025 | +11.2 % | +46.0 % |
| Vertex Pharmaceuticals Inc | Q2 2026 | +20.0 % | -23.0 % |
| Bristol myers Squibb Company | Q2 2026 | +10.5 % | -15.5 % |
| Regeneron Pharmaceuticals Inc | Q2 2026 | +109.2 % | +9.7 % |
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Pliant Therapeutics Inc's Returns and Turnover vs Peers
ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover| Company | ROA | ROI | ROE |
|---|---|---|---|
| Pliant Therapeutics Inc | - | - | - |
| Abbvie Inc | 4.68% | 9.11% | - |
| Astrazeneca Plc | 8.97% | 19.67% | 21.00% |
| Vertex Pharmaceuticals Inc | 16.88% | 19.97% | 23.31% |
| Bristol myers Squibb Company | 10.27% | 13.58% | 46.65% |
| Regeneron Pharmaceuticals Inc | 10.60% | 11.83% | 13.81% |
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).
Pliant Therapeutics Inc's Valuation vs Peers
P/E, price to sales, PEG, price to cash flow and price to book| Company | P/E | Price / Sales |
|---|---|---|
| Pliant Therapeutics Inc | 0.32 | 6.79 |
| Abbvie Inc | 75.22 | 7.32 |
| Astrazeneca Plc | 25.38 | 4.42 |
| Vertex Pharmaceuticals Inc | 30.77 | 10.70 |
| Bristol myers Squibb Company | 14.06 | 2.66 |
| Regeneron Pharmaceuticals Inc | 18.63 | 5.13 |
| PEERS AVERAGE | 43.68 | 5.85 |
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.