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Aptorum Group Limited's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Aptorum Group Limited (APM) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q4 2025
Competitors
2
Named by the company
Peer Group Market Share
-
Share of combined sales, Q4 2025
Revenue Growth Y/Y
-
Peers: 12.13 %
Net Margin
-
Peers: 22.88 %

Key Findings: Aptorum Group Limited vs Its Competitors

  • TTM: Trailing 12-month revenue of 0M vs 278,921M combined for its competitors (0.0% combined share).
  • Peer differentiation: Revenue per employee of $0.22M compares with $1.10M for the peer group (0.2x).

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

API endpoints for this dataset

https://api.csimarket.com/api/v1/companies/APM/competitors
https://api.csimarket.com/api/v1/companies/APM/relationships
https://api.csimarket.com/api/v1/companies/APM/similar
Programmatic access for models, analytics, and integration workflows.
Explore the Financial Data API

Aptorum Group Limited vs. its Competitors, Q4 2025

TTM net margin

Aptorum Group Limited -319.1 %
Competitors combined +20.3 %

TTM = trailing twelve months. Run-rate annualizes the latest quarter (×4) and compares it to TTM. In millions of $. High-Confidence Competitors are named as a competitor directly in Aptorum Group Limited reports; Similar-Size Competitors are the closest peers by market-cap rank within the same industry; Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC, all independent of the competitor list.

Competitor Financial Benchmarking - TTM Commercial

TTM revenue, latest-quarter run-rate and net income/margin benchmarked across Aptorum Group Limited and its 4 competitor groupings. Available under Commercial License.

Entity TTM Revenue Latest Q ×4 Rev Run-rate vs TTM TTM Net Income TTM Net Margin
Aptorum Group Limited $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitors combined $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
High-Confidence Competitors (1) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitor Financial Benchmarking

TTM revenue, run-rate and net margin benchmarking across Aptorum Group Limited's competitor groups requires a Commercial License.

Aptorum Group Limited's Competitor Quality Breadth

Group definitions: see Methodology: Performance Group Definitions.

Entity Profitable Expanding Above Industry Growth Distressed
Aptorum Group Limited - - - Yes
Competitors combined (31) 36% 71% 57% 47%
High-Confidence Competitors (1) 100% 100% 100% 0%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

APM Stock Performance relative to its Competitors

APM Competitors (weighted) Percent change over the selected range

Aptorum Group Limited's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
44.4%beat U.S.A. 500
Competitors Combined
(12 of 27)
0%beat U.S.A. 500
High-Confidence
(0 of 1)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Aptorum Group Limited - -
Competitors combined (27) 40.4% 63.2%
High-Confidence Competitors (1) 40.4% 63.2%
Similar-Size Competitors (0) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Aptorum Group Limited's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

APM Stock Performance relative to High-Confidence Competitors

APM High-Confidence Competitors (equal-weighted, 1) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Cypherpunk Technologies Inc 282.9% Outperformed
2 Sellas Life Sciences Group Inc 282.9% Outperformed
3 180 Life Sciences Corp 282.9% Outperformed
4 Merck and Co Inc 282.9% Outperformed
5 Eli Lilly And Company 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Aptorum Group Limited's best-performing competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Aptorum Group Limited's Comment on Competition and Industry Peers

Aptorum faces competitive risks related to the development and commercialization of its technology and drug candidates. If Aptorum or its licensors fail to obtain or maintain patent protection, competitors may develop and market similar or identical products. Protecting intellectual property rights globally presents challenges, including potential lawsuits and the risk that patents may be deemed invalid or unenforceable. Delays in clinical trials and regulatory approvals could enable competitors to bring products to market first, negatively impacting Aptorum's commercialization efforts and business prospects. The regulatory approval process is lengthy and unpredictable, and adverse events associated with Aptorum's drug candidates may affect approval and market acceptance. The competitive environment is influenced by the company's ability to secure and enforce patents, navigate regulatory requirements, and respond to competitors' activities.

Publicly Traded Peers of Aptorum Group Limited

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Aptorum Group Limited 61.83 0.43 -1.38 2
Eli Lilly And Company 1,209,663.60 86,462.00 27,579.70 50,000
Merck and Co Inc 362,398.40 66,569.00 3,170.00 75,000
Novartis Ag 317,785.25 56,674.00 13,967.00 75,267
Bristol myers Squibb Company 127,573.42 50,033.00 9,241.00 32,500
Regeneron Pharmaceuticals Inc 95,499.36 16,896.20 4,817.40 15,410
SUBTOTAL 2,123,992.51 278,921.94 56,688.71 253,170
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Sources: see Methodology: Peer & Competitor Identification, Sourcing.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Aptorum Group Limited versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Aptorum Group Limited's Competitors Named by the Company

Competitive relationships identified from Aptorum Group Limited reports and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Accelerate Technologies Pte. Ltd. Company report 85% 2022 to 2026 3
Kenon Holdings Ltd Company report 85% 2022 to 2026 3
Competitor Evidence Detail

Company report basis, confidence, active dates and source counts for Aptorum Group Limited's named competitors require a Commercial License.

Methodology: see Methodology: Peer & Competitor Identification, Sourcing.

Aptorum Group Limited's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Eli Lilly And Company Reportable 100.00 % - -
Merck and Co Inc Pharmaceutical segment 89.95 % Animal Health segment 9.27 % Corporate and Unallocated 0.78 %
Immunome Inc Single reportable segment 100.00 % - -
Novavax inc Reportable 100.00 % - -
Emergent Biosolutions Inc MCM Products 54.00 % Commercial Products 39.55 % -

Source: operating segment revenue as reported in each company's reports (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Aptorum Group Limited's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Aptorum Group Limited 62 215,689 -688,215
Eli Lilly And Company 1,209,664 1,729,240 551,594
Merck and Co Inc 362,398 887,587 42,267
Novartis Ag 317,785 752,973 185,566
Bristol myers Squibb Company 127,573 1,539,477 284,338
Regeneron Pharmaceuticals Inc 95,499 1,096,444 312,615
PEERS TOTAL 2,123,931 1,101,725 223,923
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Aptorum Group Limited's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent report. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Eli Lilly And Company United States 62.04 % Europe 18.28 % Rest of world 13.14 %
Merck and Co Inc EMEA 21.50 % Latin America 5.42 % Asia Pacific 4.32 %
Bristol myers Squibb Company United States 69.43 % Non-US 27.48 % Other Region 3.08 %
Novavax inc United States 68.88 % Rest of the world 16.68 % Europe 14.44 %
Opko Health Inc IE 27.07 % US 26.27 % CL 23.35 %

Source: revenue geography as reported in each company's reports (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

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Aptorum Group Limited's Position in Industry Market Structure

Market-capitalization share and concentration across all 20 companies in Aptorum Group Limited's industry classification, broader than the peer set above. Market cap in millions of $.

Aptorum Group Limited ranks #0 of 20 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 3,267, indicating a highly concentrated market structure (see Methodology: Market Structure & Concentration).

Rank Company Market Cap Industry Share
1 Thermo Fisher Scientific Inc 257,756 45.82 %
2 Kla Corporation 182,756 32.49 %
3 Rockwell Automation Inc 41,946 7.46 %
4 Coherent Corp 37,673 6.70 %
5 Trimble Inc 1,234 5.2%
6 Nova Ltd 1,234 5.2%
7 Onto Innovation Inc 1,234 5.2%
8 Mirion Technologies Inc 1,234 5.2%
9 Camtek Ltd 1,234 5.2%
10 908 Devices inc 1,234 5.2%
0 Aptorum Group Limited 6 0.00 %
Full Industry Market Structure

Market cap and industry share for the rest of Aptorum Group Limited's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-07-27.

Aptorum Group Limited's Valuation vs Competitive Position

Valuation multiples vs the Scientific & Technical Instruments industry average (36 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Scientific & Technical Instruments industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 60.0x -
EV / EBITDA - 24.4x -
P/B 0.0x 4.7x -4.7x
Return on Equity -5.95 % industry aggregate -24.03 %
Return on Invested Capital -5.35 % -0.95 % (avg) -4.40 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Aptorum Group Limited's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in company reports.
Metric 202320242025
Revenue Growth -66.71 %--
Operating Margin ---
Return on Invested Capital -13.50 %--5.35 %
P/E ---

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Aptorum Group Limited's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry Low Industry HHI of 3,267 (see Industry Market Structure & Concentration above)

Note: see Methodology: Porter's Five Forces. Supplier power and buyer power are covered on Aptorum Group Limited's dedicated Suppliers and Customers pages, not here.

Aptorum Group Limited's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

No rule matched.

Weaknesses

  • Return on equity 24.0 points below the industry aggregate.
  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

  • A meaningful share of competitors (46.70 %) show financial-distress signals, a possible opening to gain share.

Threats

  • Industry dominated by Thermo Fisher Scientific Inc , holding 45.82 % of industry market cap.

Methodology: see Methodology: SWOT Analysis.

Aptorum Group Limited's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Aptorum Group Limited 0.75 0.78 0.15 0.02
Eli Lilly And Company 0.16 1.44 1.44 0.67
Merck and Co Inc 0.40 1.46 1.01 0.51
Novartis Ag 0.42 1.12 0.02 0.51
Bristol myers Squibb Company 0.48 1.44 2.12 0.57
Regeneron Pharmaceuticals Inc 0.58 3.56 0.06 0.40
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Aptorum Group Limited's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Aptorum Group LimitedQ4 2025----
Eli Lilly And CompanyQ3 2026+38.6 %+6.2 %+15.6 %-9.1 %
Merck and Co Inc Q2 2026+5.1 %+2.0 %--
Novartis AgQ4 2025+9.6 %+9.6 %+17.0 %+17.0 %
Bristol myers Squibb CompanyQ3 2026+6.9 %+0.7 %-1.5 %-34.8 %
Regeneron Pharmaceuticals Inc Q3 2026+36.3 %+19.2 %+33.5 %+50.3 %
PEERS TOTAL+14.2 %+6.7 %-10.6 %+20.1 %
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Aptorum Group Limited's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Aptorum Group LimitedQ4 2025----
Eli Lilly And CompanyQ3 2026+30.7 %+20.3 %+52.2 %+8.4 %
Merck and Co Inc Q2 2026+23.6 %+4.8 %+16.9 %-9.9 %
Novartis AgQ4 2025+18.3 %+18.3 %+13.3 %+13.3 %
Bristol myers Squibb CompanyQ3 2026+20.7 %+11.3 %+7.5 %+12.8 %
Regeneron Pharmaceuticals Inc Q3 2026+104.1 %-0.5 %+49.1 %+25.0 %
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Aptorum Group Limited's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Aptorum Group Limited-----
Eli Lilly And Company21.24%32.00%83.65%4.410.89
Merck and Co Inc 2.42%3.24%6.59%5.472.79
Novartis Ag12.59%12.62%30.00%6.34-
Bristol myers Squibb Company10.47%13.59%43.83%4.775.65
Regeneron Pharmaceuticals Inc 11.50%13.00%15.07%2.640.60
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Aptorum Group Limited's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Aptorum Group Limited-143.33-23.982.67
Eli Lilly And Company43.9613.990.29-30.04
Merck and Co Inc 118.325.44--8.63
Novartis Ag22.735.6130.5027.736.83
Bristol myers Squibb Company13.772.550.20-5.45
Regeneron Pharmaceuticals Inc 20.005.651.3082.432.85
PEERS AVERAGE37.477.624,468.1911.25
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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