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Tectonic Therapeutic Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Tectonic Therapeutic Inc (TECX) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q2 2026
Competitors Tracked
35
Publicly traded peers
Peer Group Market Share
-
Share of combined sales, Q2 2026
Revenue Growth Y/Y
-
Peers: 135.68 %
Net Margin
-
Peers: -90.35 %

Key Findings: Tectonic Therapeutic Inc vs Its Competitors

  • Scale: Tectonic Therapeutic Inc ranks #59 of 165 companies by market capitalization in the Biotechnology & Pharmaceuticals industry, holding 0.0% of industry market cap.

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/TECX/competitors
https://api.csimarket.com/api/v1/companies/TECX/relationships
https://api.csimarket.com/api/v1/companies/TECX/similar
Programmatic access for models, analytics, and integration workflows.

Tectonic Therapeutic Inc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Tectonic Therapeutic Inc - - - Yes
Competitors combined (35) 19% 63% 53% 52%
High-Confidence Competitors (3) 100% 100% 50% 67%
Similar-Size Competitors (10) 17% 80% 60% 70%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

TECX Stock Performance relative to its Competitors

TECX Competitors (weighted) Percent change over the selected range

Tectonic Therapeutic Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
33.3%beat U.S.A. 500
Competitors Combined
(11 of 33)
0%beat U.S.A. 500
High-Confidence
(0 of 3)
55.6%beat U.S.A. 500
Similar-Size
(5 of 9)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Tectonic Therapeutic Inc 52.30 % Outperformed
Competitors combined (33) 40.4% 63.2%
High-Confidence Competitors (3) 40.4% 63.2%
Similar-Size Competitors (9) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Tectonic Therapeutic Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

TECX Stock Performance relative to High-Confidence Competitors

TECX High-Confidence Competitors (equal-weighted, 3) Percent change over the selected range

TECX Stock Performance relative to Similar-Size Competitors

TECX Similar-Size Competitors (equal-weighted, 10) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Relay Therapeutics Inc 282.9% Outperformed
2 Century Therapeutics inc 282.9% Outperformed
3 Fate Therapeutics Inc 282.9% Outperformed
4 Krystal Biotech Inc 282.9% Outperformed
5 Contextlogic Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Tectonic Therapeutic Inc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Tectonic Therapeutic Inc's Comment on Competition and Industry Peers

The company operates in the biotechnology and pharmaceutical industry, characterized by rapid technological advancements and a strong focus on intellectual property. It faces competition from major pharmaceutical, specialty pharmaceutical, and biotechnology companies, as well as academic, governmental, and private research institutions worldwide. Competitors often possess greater financial resources and expertise in drug development and commercialization. Smaller or early-stage companies may also be competitors, particularly through collaborations with larger firms. Specific competitors include AstraZeneca, which is conducting a Phase 2b trial for a small molecule relaxin targeting chronic heart failure (both HFpEF and HFrEF). In the hereditary hemorrhagic telangiectasia (HHT) space, Vaderis, Terremoto, and Atavistik are engaged in development efforts.

Publicly Traded Peers of Tectonic Therapeutic Inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Tectonic Therapeutic Inc 438.92 - -85.79 60
Biontech Se 23,889.63 3,214.29 -1,272.43 7,807
Krystal Biotech Inc 10,194.07 440.48 241.46 295
Crispr Therapeutics Ag 5,284.85 13.39 -451.14 201
Relay Therapeutics Inc 3,577.25 0.70 -286.04 192
Beam Therapeutics Inc 2,528.88 156.04 -85.43 511
SUBTOTAL 59,594.05 5,538.49 -3,633.53 13,755
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Sources: Tectonic Therapeutic Inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Tectonic Therapeutic Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Tectonic Therapeutic Inc's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Terremoto Named by the company 85% 2022 to 2026 3
BioMarin Pharmaceutical Inc. Named by the company 85% 2022 to 2026 3
Tenax Therapeutics Inc Named by the company 85% 2022 to 2026 3
AstraZeneca Named by the company 85% 2022 to 2026 3
The University of Manchester Named by the company 85% 2022 to 2026 3
GenStem Therapeutics, Inc. Named by the company 85% 2022 to 2026 3
Atavistik Named by the company 85% 2022 to 2026 3
Vaderis Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for Tectonic Therapeutic Inc's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

Tectonic Therapeutic Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Immunocore Holdings Plc Reportable 100.00 % - -
Ginkgo Bioworks Holdings Inc Reportable 100.00 % - -
Prime Medicine Inc Reportable 100.00 % - -
Century Therapeutics inc Single reportable segment 100.00 % - -
Editas Medicine Inc Reportable 100.00 % - -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Tectonic Therapeutic Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Tectonic Therapeutic Inc 439 - -1,429,783
Biontech Se 23,890 411,719 -162,986
Krystal Biotech Inc 10,194 1,493,166 818,525
Crispr Therapeutics Ag 5,285 66,627 -2,244,473
Relay Therapeutics Inc 3,577 3,620 -1,489,776
Beam Therapeutics Inc 2,529 305,352 -167,176
PEERS TOTAL 59,155 404,417 -259,054
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Tectonic Therapeutic Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Krystal Biotech Inc United States 75.19 % Europe 17.77 % Japan 7.04 %
4d Molecular Therapeutics Inc JP 97.05 % US 2.95 % -
Caribou Biosciences Inc United States 94.16 % Non-US 5.84 % -

Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

Tectonic Therapeutic Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 159 companies in Tectonic Therapeutic Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Tectonic Therapeutic Inc ranks #59 of 159 companies by market capitalization in its industry, holding 0.05 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 1,320, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Amgen Inc 227,218 25.72 %
2 Gilead Sciences Inc 188,277 21.31 %
3 Moderna Inc 81,799 9.26 %
4 Argenx Se 63,476 7.19 %
5 Revolution Medicines Inc 1,234 5.2%
6 Biogen Inc 1,234 5.2%
7 Biontech Se 1,234 5.2%
8 Exelixis Inc 1,234 5.2%
9 Neurocrine Biosciences Inc 1,234 5.2%
10 Halozyme Therapeutics Inc 1,234 5.2%
59 Tectonic Therapeutic Inc 439 0.05 %
Full Industry Market Structure

Market cap and industry share for the rest of Tectonic Therapeutic Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-29.

Tectonic Therapeutic Inc's Same-Size Peers & Stock Performance

Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.
Rank Company Market Cap TTM Return 3M Momentum Beta Sharpe (1Y)
54 Allogene Therapeutics Inc 539 31.20 % -21.53 % 1.65 0.68
55 Prime Medicine Inc 533 -41.21 % -24.56 % 2.21 -0.21
56 Zura Bio Limited 518 69.50 % -23.79 % 1.57 0.96
57 Valneva Se 517 -34.50 % 17.78 % 0.88 -0.32
58 Autolus Therapeutics Plc 1,234 12.3% 4.5% 1.10 0.80
59 Tectonic Therapeutic Inc 439 52.27 % -34.28 % 1.38 0.99
60 Eikon Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
61 Kyverna Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
62 Agenus Inc 1,234 12.3% 4.5% 1.10 0.80
63 Fennec Pharmaceuticals Inc 1,234 12.3% 4.5% 1.10 0.80
64 Regenxbio Inc 1,234 12.3% 4.5% 1.10 0.80
Full Same-Size Peer Performance

Market cap, return, momentum, beta and Sharpe ratio for the rest of Tectonic Therapeutic Inc's same-size peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-09-29. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.

Tectonic Therapeutic Inc's Valuation vs Competitive Position

Valuation multiples vs the Biotechnology & Pharmaceuticals industry average (93 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Biotechnology & Pharmaceuticals industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 26.7x -
EV / EBITDA - 21.3x -
P/B 2.4x 5.1x -2.7x
Return on Equity -35.26 % industry aggregate -31.83 %
Return on Invested Capital -19.42 % -6.17 % (avg) -13.25 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Tectonic Therapeutic Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 2019202020212022202320242025
Revenue Growth -------
Operating Margin -------
Return on Invested Capital -25.55 %-25.07 %-28.82 %-45.31 %--21.15 %-15.22 %
P/E -------

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Tectonic Therapeutic Inc's BCG Growth-Share Matrix

Relative market share (vs Tectonic Therapeutic Inc's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.

Question Mark Star Dog Cash Cow Relative Market Share (vs largest competitor) Industry Revenue Growth (%) Tectonic Therapeutic Inc

Tectonic Therapeutic Inc falls in the Question Mark quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 10.0% (median, trailing 12 months).

Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.

Tectonic Therapeutic Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 1,320 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Tectonic Therapeutic Inc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Tectonic Therapeutic Inc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Tectonic Therapeutic Inc's Industry Attractiveness & Competitive Strength

A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.

High Strength
Medium Strength
Low Strength
High Attractiveness
Invest / Grow
Invest / Grow
Selective
Medium Attractiveness
Invest / Grow
Selective
Harvest
Low Attractiveness
Selective
Harvest
Harvest / Divest Tectonic Therapeutic Inc

Tectonic Therapeutic Inc falls in the Low attractiveness / Low strength cell: Harvest / Divest.

Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.

Tectonic Therapeutic Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

  • Outperforming the U.S.A. 500 over the trailing 12 months.

Weaknesses

  • Return on equity 31.8 points below the industry aggregate.
  • Low relative market share vs the industry leader (0.00x).
  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

  • Industry revenue growing at a healthy 10.0% median pace.
  • A meaningful share of tracked competitors (51.60 %) show financial-distress signals, a possible opening to gain share.

Threats

No rule matched.

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Tectonic Therapeutic Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Tectonic Therapeutic Inc 23.28 23.64 - -
Biontech Se 3.58 7.54 - 0.13
Krystal Biotech Inc 5.21 9.38 - 0.32
Crispr Therapeutics Ag 2.51 16.26 0.16 0.01
Relay Therapeutics Inc 3.61 20.10 - 0.00
Beam Therapeutics Inc 4.72 11.07 0.05 0.11
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Tectonic Therapeutic Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Tectonic Therapeutic Inc Q2 2026----
Biontech SeQ4 2025+4.3 %+4.3 %--
Krystal Biotech Inc Q2 2026+24.1 %+2.5 %+42.9 %-2.1 %
Crispr Therapeutics AgQ2 2026+1,041.4 %+598.3 %--
Relay Therapeutics Inc Q2 2026-48.3 %-88.3 %--
Beam Therapeutics Inc Q2 2026-94.2 %-98.5 %--
PEERS TOTAL+16.7 %+15.3 %--
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Tectonic Therapeutic Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Tectonic Therapeutic Inc Q2 2026---+315.8 %
Biontech SeQ4 2025+18.6 %+18.6 %-38.9 %-38.9 %
Krystal Biotech Inc Q2 2026--+87.2 %-50.1 %
Crispr Therapeutics AgQ2 2026--+453.8 %+28.6 %
Relay Therapeutics Inc Q2 2026----
Beam Therapeutics Inc Q2 2026---23.0 %+8.2 %
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Tectonic Therapeutic Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Tectonic Therapeutic Inc -----
Biontech Se---2.96-
Krystal Biotech Inc 17.65%19.16%19.34%3.37-
Crispr Therapeutics Ag-----
Relay Therapeutics Inc -----
Beam Therapeutics Inc -----
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Tectonic Therapeutic Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Tectonic Therapeutic Inc ----1.96
Biontech Se-7.43-2.191.11
Krystal Biotech Inc 41.5723.140.44137.927.50
Crispr Therapeutics Ag-394.63-56.103.03
Relay Therapeutics Inc -5,147.12-565.484.02
Beam Therapeutics Inc -16.21--2.37
PEERS AVERAGE-10.765.621.97
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.