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Tectonic Therapeutic Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Tectonic Therapeutic Inc (TECX) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q2 2026
Competitors
10
Named by the company
Peer Group Market Share
-
Share of combined sales, Q2 2026
Revenue Growth Y/Y
-
Peers: 135.68 %
Net Margin
-
Peers: -90.35 %

Key Findings: Tectonic Therapeutic Inc vs Its Competitors

  • Scale: Tectonic Therapeutic Inc ranks #62 of 165 companies by market capitalization in the Biotechnology & Pharmaceuticals industry, holding 0.0% of industry market cap.

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

API endpoints for this dataset

https://api.csimarket.com/api/v1/companies/TECX/competitors
https://api.csimarket.com/api/v1/companies/TECX/relationships
https://api.csimarket.com/api/v1/companies/TECX/similar
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Tectonic Therapeutic Inc's Competitor Quality Breadth

Group definitions: see Methodology: Performance Group Definitions.

Entity Profitable Expanding Above Industry Growth Distressed
Tectonic Therapeutic Inc - - - Yes
Competitors combined (35) 33% 67% 61% 69%
High-Confidence Competitors (5) 50% 75% 50% 40%
Similar-Size Competitors (10) 0% 75% 50% 80%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

TECX Stock Performance relative to its Competitors

TECX Competitors (weighted) Percent change over the selected range

Tectonic Therapeutic Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
34.4%beat U.S.A. 500
Competitors Combined
(11 of 32)
20%beat U.S.A. 500
High-Confidence
(1 of 5)
44.4%beat U.S.A. 500
Similar-Size
(4 of 9)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Tectonic Therapeutic Inc 19.30 % Outperformed
Competitors combined (32) 40.4% 63.2%
High-Confidence Competitors (5) 40.4% 63.2%
Similar-Size Competitors (9) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Tectonic Therapeutic Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

TECX Stock Performance relative to High-Confidence Competitors

TECX High-Confidence Competitors (equal-weighted, 5) Percent change over the selected range

TECX Stock Performance relative to Similar-Size Competitors

TECX Similar-Size Competitors (equal-weighted, 10) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Jasper Therapeutics Inc 282.9% Outperformed
2 Century Therapeutics inc 282.9% Outperformed
3 Relay Therapeutics Inc 282.9% Outperformed
4 Contextlogic Inc 282.9% Outperformed
5 Tourmaline Bio Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Tectonic Therapeutic Inc's best-performing competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Tectonic Therapeutic Inc's Comment on Competition and Industry Peers

The company operates in the biotechnology and pharmaceutical industry, characterized by rapid technological advancements and a strong focus on intellectual property. It faces competition from major pharmaceutical, specialty pharmaceutical, and biotechnology companies, as well as academic, governmental, and private research institutions worldwide. Competitors often possess greater financial resources and expertise in drug development and commercialization. Smaller or early-stage companies may also be competitors, particularly through collaborations with larger firms. Specific competitors include AstraZeneca, which is conducting a Phase 2b trial for a small molecule relaxin targeting chronic heart failure (both HFpEF and HFrEF). In the hereditary hemorrhagic telangiectasia (HHT) space, Vaderis, Terremoto, and Atavistik are engaged in development efforts.

Publicly Traded Peers of Tectonic Therapeutic Inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Tectonic Therapeutic Inc 391.42 - -85.79 60
Biontech Se 21,151.17 3,243.68 -1,284.50 7,807
Krystal Biotech Inc 9,278.54 470.03 225.17 295
Crispr Therapeutics Ag 4,843.83 25.17 -456.14 201
Relay Therapeutics Inc 3,773.00 0.70 -286.04 192
Beam Therapeutics Inc 2,765.09 146.64 -107.10 511
SUBTOTAL 55,807.95 5,570.12 -2,877.45 13,755
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Sources: see Methodology: Peer & Competitor Identification, Sourcing.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Tectonic Therapeutic Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Tectonic Therapeutic Inc's Competitors Named by the Company

Competitive relationships identified from Tectonic Therapeutic Inc reports and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Tenax Therapeutics Inc Company report 85% 2022 to 2026 3
AstraZeneca Company report 85% 2022 to 2026 3
Atavistik Company report 85% 2022 to 2026 3
Vaderis Company report 85% 2022 to 2026 3
Terremoto Company report 85% 2022 to 2026 3
Entrada Therapeutics Inc Company report 85% 2022 to 2026 3
The University of Manchester Company report 85% 2022 to 2026 3
GenStem Therapeutics, Inc. Company report 85% 2022 to 2026 3
Uniqure N v Company report 85% 2022 to 2026 3
BioMarin Pharmaceutical Inc. Company report 85% 2022 to 2026 3
Competitor Evidence Detail

Company report basis, confidence, active dates and source counts for Tectonic Therapeutic Inc's named competitors require a Commercial License.

Methodology: see Methodology: Peer & Competitor Identification, Sourcing.

Tectonic Therapeutic Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Immunocore Holdings Plc Reportable 100.00 % - -
Prime Medicine Inc Reportable 100.00 % - -
Ginkgo Bioworks Holdings Inc Reportable 100.00 % - -
Century Therapeutics inc Single reportable segment 100.00 % - -
Editas Medicine Inc Reportable 100.00 % - -

Source: operating segment revenue as reported in each company's reports (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Tectonic Therapeutic Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Tectonic Therapeutic Inc 391 - -1,429,783
Biontech Se 21,151 415,483 -164,532
Krystal Biotech Inc 9,279 1,593,305 763,281
Crispr Therapeutics Ag 4,844 125,234 -2,269,328
Relay Therapeutics Inc 3,773 3,620 -1,489,776
Beam Therapeutics Inc 2,765 286,975 -209,597
PEERS TOTAL 55,417 406,727 -203,845
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Tectonic Therapeutic Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent report. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Krystal Biotech Inc United States 74.86 % Europe 18.26 % Japan 6.88 %
4d Molecular Therapeutics Inc JP 97.05 % US 2.95 % -
Caribou Biosciences Inc United States 76.60 % Non-US 23.40 % -

Source: revenue geography as reported in each company's reports (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

Tectonic Therapeutic Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 158 companies in Tectonic Therapeutic Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Tectonic Therapeutic Inc ranks #62 of 158 companies by market capitalization in its industry, holding 0.04 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 1,353, indicating a unconcentrated market structure (see Methodology: Market Structure & Concentration).

Rank Company Market Cap Industry Share
1 Amgen Inc 250,468 26.02 %
2 Gilead Sciences Inc 207,444 21.55 %
3 Moderna Inc 101,168 10.51 %
4 Argenx Se 61,223 6.36 %
5 Revolution Medicines Inc 1,234 5.2%
6 Biogen Inc 1,234 5.2%
7 Biontech Se 1,234 5.2%
8 Mesoblast Limited 1,234 5.2%
9 Exelixis Inc 1,234 5.2%
10 Neurocrine Biosciences Inc 1,234 5.2%
62 Tectonic Therapeutic Inc 391 0.04 %
Full Industry Market Structure

Market cap and industry share for the rest of Tectonic Therapeutic Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-11-06.

Tectonic Therapeutic Inc's Same-Size Peers & Stock Performance

Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.
Rank Company Market Cap TTM Return 3M Momentum Beta Sharpe (1Y)
57 Aura Biosciences Inc 622 17.37 % -16.54 % 1.19 0.53
58 Zura Bio Limited 519 5.51 % -31.97 % 1.60 0.50
59 C4 Therapeutics Inc 405 26.58 % -26.47 % 2.13 0.70
60 Regenxbio Inc 404 -34.02 % -28.14 % 1.72 -0.01
61 X4 Pharmaceuticals Inc 1,234 12.3% 4.5% 1.10 0.80
62 Tectonic Therapeutic Inc 391 19.25 % -42.30 % 1.42 0.74
63 Fennec Pharmaceuticals Inc 1,234 12.3% 4.5% 1.10 0.80
64 Century Therapeutics inc 1,234 12.3% 4.5% 1.10 0.80
65 Allogene Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
66 Autolus Therapeutics Plc 1,234 12.3% 4.5% 1.10 0.80
67 Eikon Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
Full Same-Size Peer Performance

Market cap, return, momentum, beta and Sharpe ratio for the rest of Tectonic Therapeutic Inc's same-size peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-11-06. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.

Tectonic Therapeutic Inc's Valuation vs Competitive Position

Valuation multiples vs the Biotechnology & Pharmaceuticals industry average (159 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Biotechnology & Pharmaceuticals industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 26.5x -
EV / EBITDA - 16.7x -
P/B 2.3x 5.1x -2.8x
Return on Equity -35.26 % industry aggregate -33.72 %
Return on Invested Capital -19.42 % -11.17 % (avg) -8.25 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Tectonic Therapeutic Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in company reports.
Metric 2019202020212022202320242025
Revenue Growth -------
Operating Margin -------
Return on Invested Capital -25.55 %-25.07 %-28.82 %-45.31 %--35.00 %-15.22 %
P/E -------

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Tectonic Therapeutic Inc's BCG Growth-Share Matrix

See Methodology: BCG Growth-Share Matrix for how relative share and growth are calculated and thresholded.

Question Mark Star Dog Cash Cow Relative Market Share (vs largest competitor) Industry Revenue Growth (%) Tectonic Therapeutic Inc

Tectonic Therapeutic Inc falls in the Dog quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 9.0% (median, trailing 12 months).

Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.

Tectonic Therapeutic Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 1,353 (see Industry Market Structure & Concentration above)

Note: see Methodology: Porter's Five Forces. Supplier power and buyer power are covered on Tectonic Therapeutic Inc's dedicated Suppliers and Customers pages, not here.

Tectonic Therapeutic Inc's Industry Attractiveness & Competitive Strength

See Methodology: GE/McKinsey Matrix for how the two axes are built.

High Strength
Medium Strength
Low Strength
High Attractiveness
Invest / Grow
Invest / Grow
Selective
Medium Attractiveness
Invest / Grow
Selective
Harvest
Low Attractiveness
Selective
Harvest
Harvest / Divest Tectonic Therapeutic Inc

Tectonic Therapeutic Inc falls in the Low attractiveness / Low strength cell: Harvest / Divest.

Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.

Tectonic Therapeutic Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

  • Outperforming the U.S.A. 500 over the trailing 12 months.

Weaknesses

  • Return on equity 33.7 points below the industry aggregate.
  • Low relative market share vs the industry leader (0.00x).
  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

  • A meaningful share of competitors (68.60 %) show financial-distress signals, a possible opening to gain share.

Threats

No rule matched.

Methodology: see Methodology: SWOT Analysis.

Tectonic Therapeutic Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Tectonic Therapeutic Inc 23.28 23.64 - -
Biontech Se 3.58 7.54 - 0.13
Krystal Biotech Inc 4.80 8.80 - 0.32
Crispr Therapeutics Ag 2.24 16.26 0.25 0.01
Relay Therapeutics Inc 3.61 20.10 - 0.00
Beam Therapeutics Inc 5.97 14.30 0.07 0.10
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Tectonic Therapeutic Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Tectonic Therapeutic Inc Q2 2026----
Biontech SeQ4 2025+9.0 %+9.0 %--
Krystal Biotech Inc Q3 2026+30.2 %+6.8 %-20.5 %+15.2 %
Crispr Therapeutics AgQ3 2026+1,325.1 %+24.4 %--
Relay Therapeutics Inc Q2 2026-48.3 %-88.3 %--
Beam Therapeutics Inc Q3 2026-96.8 %-37.3 %--
PEERS TOTAL+18.9 %+15.5 %--
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Tectonic Therapeutic Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Tectonic Therapeutic Inc Q2 2026---+315.8 %
Biontech SeQ4 2025+23.9 %+23.9 %-36.1 %-36.1 %
Krystal Biotech Inc Q3 2026---41.5 %-72.1 %
Crispr Therapeutics AgQ3 2026--+459.5 %-36.1 %
Relay Therapeutics Inc Q2 2026----
Beam Therapeutics Inc Q3 2026---75.8 %-49.8 %
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Tectonic Therapeutic Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Tectonic Therapeutic Inc -----
Biontech Se---2.995.59
Krystal Biotech Inc 15.48%16.91%17.02%3.57-
Crispr Therapeutics Ag-----
Relay Therapeutics Inc -----
Beam Therapeutics Inc -----
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Tectonic Therapeutic Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Tectonic Therapeutic Inc ----1.75
Biontech Se-6.52-1.930.94
Krystal Biotech Inc 40.7119.740.51132.106.46
Crispr Therapeutics Ag-192.43--2.94
Relay Therapeutics Inc -5,428.78-596.434.24
Beam Therapeutics Inc -18.86--2.90
PEERS AVERAGE-10.025.321.79
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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