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Shattuck Labs Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Shattuck Labs Inc (STTK) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q2 2026
Competitors Tracked
59
Publicly traded peers
Peer Group Market Share
-
Share of combined sales, Q2 2026
Revenue Growth Y/Y
-
Peers: 8.67 %
Net Margin
-
Peers: 11.19 %

Key Findings: Shattuck Labs Inc vs Its Competitors

  • TTM: Trailing 12-month revenue of 6M vs 142,933M combined for tracked competitors (0.0% combined share).
  • Scale: Shattuck Labs Inc ranks #158 of 544 companies by market capitalization in the Major Pharmaceutical Preparations industry, holding 0.0% of industry market cap.
  • Peer differentiation: Revenue per employee of $0.16M compares with $0.91M for the peer group (0.2x).

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/STTK/competitors
https://api.csimarket.com/api/v1/companies/STTK/relationships
https://api.csimarket.com/api/v1/companies/STTK/similar
Programmatic access for models, analytics, and integration workflows.

Shattuck Labs Inc vs. its Competitors, Q2 2026

TTM net margin

Shattuck Labs Inc -820.5 %
Competitors combined +12.1 %

TTM = trailing twelve months. Run-rate annualizes the latest quarter (×4) and compares it to TTM. In millions of $. High-Confidence Competitors are named as a competitor directly in an SEC filing; Similar-Size Competitors are the closest peers by market-cap rank within the same industry; Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC, all independent of the competitor list.

Competitor Financial Benchmarking - TTM Commercial

TTM revenue, latest-quarter run-rate and net income/margin benchmarked across Shattuck Labs Inc and its 4 competitor groupings. Available under Commercial License.

Entity TTM Revenue Latest Q ×4 Rev Run-rate vs TTM TTM Net Income TTM Net Margin
Shattuck Labs Inc $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitors combined $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
High-Confidence Competitors (12) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Similar-Size Competitors (10) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitor Financial Benchmarking

TTM revenue, run-rate and net margin benchmarking across Shattuck Labs Inc's competitor groups requires a Commercial License.

Shattuck Labs Inc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Shattuck Labs Inc - - - No
Competitors combined (59) 44% 79% 64% 36%
High-Confidence Competitors (17) 75% 67% 25% 24%
Similar-Size Competitors (10) 20% 60% 60% 40%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

STTK Stock Performance relative to its Competitors

STTK Competitors (weighted) Percent change over the selected range

Shattuck Labs Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
49.1%beat U.S.A. 500
Competitors Combined
(26 of 53)
70.6%beat U.S.A. 500
High-Confidence
(12 of 17)
55.6%beat U.S.A. 500
Similar-Size
(5 of 9)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Shattuck Labs Inc 180.00 % Outperformed
Competitors combined (53) 40.4% 63.2%
High-Confidence Competitors (17) 40.4% 63.2%
Similar-Size Competitors (9) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Shattuck Labs Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

STTK Stock Performance relative to High-Confidence Competitors

STTK High-Confidence Competitors (equal-weighted, 18) Percent change over the selected range

STTK Stock Performance relative to Similar-Size Competitors

STTK Similar-Size Competitors (equal-weighted, 10) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Adlai Nortye Ltd 282.9% Outperformed
2 Iovance Biotherapeutics inc 282.9% Outperformed
3 Spyre Therapeutics Inc 282.9% Outperformed
4 Day One Biopharmaceuticals Inc 282.9% Outperformed
5 Nurix Therapeutics Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Shattuck Labs Inc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Shattuck Labs Inc's Comment on Competition and Industry Peers

The company operates in a competitive environment that includes large pharmaceutical and biotechnology firms, academic institutions, government agencies, and other research organizations focused on developing therapies for immune-mediated diseases such as inflammatory bowel disease (IBD). Key competitors with commercialized or developing therapies in this area include Abbvie, Absci Corporation, Johnson & Johnson, Merck, Novartis, Pfizer, Roche/Genentech, Sanofi, Takeda, and Teva. For its lead product candidate, SL-325, the company is aware of other clinical-stage therapeutics targeting the TL1A/DR3 axis, including TL1A-targeting antibodies like duvakitug developed by Absci Corporation. Many competitors possess greater financial resources and expertise in drug development and commercialization. Industry consolidation through mergers and acquisitions may further concentrate resources among fewer competitors, while smaller or early-stage companies may also present competition through collaborations with larger firms.

Publicly Traded Peers of Shattuck Labs Inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Shattuck Labs Inc 848.76 6.41 -52.57 40
Novartis Ag 284,863.05 56,674.00 13,967.00 75,267
Astrazeneca Plc 256,496.02 58,739.00 10,233.00 83,100
Pfizer Inc 163,675.28 63,696.00 4,370.00 75,000
Vertex Pharmaceuticals Inc 134,421.50 12,587.20 4,405.20 405
Bristol myers Squibb Company 128,737.28 49,186.00 9,274.00 32,500
SUBTOTAL 1,170,586.31 259,810.10 39,886.41 285,207
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Sources: Shattuck Labs Inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Shattuck Labs Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Shattuck Labs Inc's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Pfizer Named by the company 85% 2022 to 2026 3
Bristol Myers Squibb Named by the company 85% 2022 to 2026 3
Novartis Named by the company 85% 2022 to 2026 3
Teva Named by the company 85% 2022 to 2026 3
Portage Biotech Inc Named by the company 85% 2022 to 2026 3
AstraZeneca/MedImmune Named by the company 85% 2022 to 2026 3
Gilead Named by the company 85% 2022 to 2026 3
Merck Named by the company 85% 2022 to 2026 3
Spyre Therapeutics, Inc. Named by the company 85% 2022 to 2026 3
Xencor, Inc. Named by the company 85% 2022 to 2026 3
Curis Inc Named by the company 85% 2022 to 2026 3
Adicet Bio Named by the company 85% 2022 to 2026 3
evorpacept Named by the company 85% 2022 to 2026 3
lemzoparlimab Named by the company 85% 2022 to 2026 3
Roche/Genentech Named by the company 85% 2022 to 2026 3
TTI-621 Named by the company 85% 2022 to 2026 3
Abbvie Named by the company 85% 2022 to 2026 3
ImCheck Therapeutics Named by the company 85% 2022 to 2026 3
Takeda Named by the company 85% 2022 to 2026 3
Lava Therapeutics Nv Named by the company 85% 2022 to 2026 3
APX005M Named by the company 85% 2022 to 2026 3
Gamma Delta Therapeutics Named by the company 85% 2022 to 2026 3
magrolimab Named by the company 85% 2022 to 2026 3
Sanofi Named by the company 85% 2022 to 2026 3
TTI-622 Named by the company 85% 2022 to 2026 3
Aptevo Therapeutics Inc Named by the company 85% 2022 to 2026 3
Absci Corporation Named by the company 85% 2022 to 2026 3
DSP107 Named by the company 85% 2022 to 2026 3
Johnson & Johnson Named by the company 85% 2022 to 2026 3
Astrazeneca Plc Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for Shattuck Labs Inc's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

Shattuck Labs Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Pfizer Inc U.S. Commercial Division 52.92 % International Commercial Division 36.88 % Global Hospital and Biosimilars Division 7.72 %
Vertex Pharmaceuticals Inc Pharmaceuticals 100.00 % - -
Madrigal Pharmaceuticals Inc Reportable 100.00 % - -
Hutchmed china Limited Other Ventures segment 47.94 % Marketed Products Subsegment 39.08 % Research and Development Subsegment 12.98 %
Biomarin Pharmaceutical Inc Reportable 100.00 % - -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Shattuck Labs Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Shattuck Labs Inc 849 160,175 -1,314,200
Novartis Ag 284,863 752,973 185,566
Astrazeneca Plc 256,496 706,847 123,141
Pfizer Inc 163,675 849,280 58,267
Vertex Pharmaceuticals Inc 134,421 31,079,506 10,877,037
Bristol myers Squibb Company 128,737 1,513,415 285,354
PEERS TOTAL 1,169,738 911,058 140,055
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Shattuck Labs Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Pfizer Inc United States 58.91 % International Developed Markets 24.90 % International Emerging Markets 16.19 %
Vertex Pharmaceuticals Inc United States 61.68 % Europe 29.33 % Other Countries Outside of the United States and Europe 8.99 %
Bristol myers Squibb Company United States 67.79 % Non-US 29.98 % Other Region 2.24 %
Jazz Pharmaceuticals Plc United States 89.79 % Europe 8.64 % Other Countries 1.56 %
Hutchmed china Limited CN 74.28 % United States and Others 25.72 % -

Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

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Shattuck Labs Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 498 companies in Shattuck Labs Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Shattuck Labs Inc ranks #158 of 498 companies by market capitalization in its industry, holding 0.02 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 824, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Eli Lilly And Company 1,058,704 19.37 %
2 Johnson and Johnson 652,898 11.95 %
3 Beone Medicines Ltd 549,864 10.06 %
4 Abbvie Inc 466,251 8.53 %
5 Merck and Co Inc 1,234 5.2%
6 Novartis Ag 1,234 5.2%
7 Abbott Laboratories 1,234 5.2%
8 Novo Nordisk A 1,234 5.2%
9 Pfizer Inc 1,234 5.2%
10 Vertex Pharmaceuticals Inc 1,234 5.2%
158 Shattuck Labs Inc 849 0.02 %
Full Industry Market Structure

Market cap and industry share for the rest of Shattuck Labs Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-29.

Shattuck Labs Inc's Same-Size Peers & Stock Performance

Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.
Rank Company Market Cap TTM Return 3M Momentum Beta Sharpe (1Y)
153 Olema Pharmaceuticals Inc 892 -10.04 % -33.01 % 0.88 0.37
154 Theravance Biopharma inc 880 - - 0.52 0.57
155 Climb Bio Inc 876 442.72 % -12.89 % 1.20 2.19
156 Cryoport inc 874 88.10 % 13.62 % 1.73 1.43
157 Jade Biosciences Inc 1,234 12.3% 4.5% 1.10 0.80
158 Shattuck Labs Inc 849 180.04 % -11.81 % 1.78 1.66
159 Moonlake Immunotherapeutics 1,234 12.3% 4.5% 1.10 0.80
160 Ardelyx inc 1,234 12.3% 4.5% 1.10 0.80
161 Geron Corporation 1,234 12.3% 4.5% 1.10 0.80
162 Annexon Inc 1,234 12.3% 4.5% 1.10 0.80
163 Lexicon Pharmaceuticals Inc 1,234 12.3% 4.5% 1.10 0.80
Full Same-Size Peer Performance

Market cap, return, momentum, beta and Sharpe ratio for the rest of Shattuck Labs Inc's same-size peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-09-29. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.

Shattuck Labs Inc's Valuation vs Competitive Position

Valuation multiples vs the Major Pharmaceutical Preparations industry average (342 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 25.1x -
EV / EBITDA - 17.3x -
P/B 6.6x 4.5x +2.1x
Return on Equity -43.57 % industry aggregate -60.82 %
Return on Invested Capital -22.95 % -2.95 % (avg) -20.00 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Shattuck Labs Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 20202021202220242025
Revenue Growth 500.00 %202.16 %---
Operating Margin -371.76 %-150.81 %---
Return on Invested Capital -26.52 %-7.87 %-24.14 %-38.24 %-33.88 %
P/E -----

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Shattuck Labs Inc's BCG Growth-Share Matrix

Relative market share (vs Shattuck Labs Inc's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.

Question Mark Star Dog Cash Cow Relative Market Share (vs largest competitor) Industry Revenue Growth (%) Shattuck Labs Inc

Shattuck Labs Inc falls in the Dog quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 8.0% (median, trailing 12 months).

Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.

Shattuck Labs Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 824 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Shattuck Labs Inc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Shattuck Labs Inc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Shattuck Labs Inc's Industry Attractiveness & Competitive Strength

A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.

High Strength
Medium Strength
Low Strength
High Attractiveness
Invest / Grow
Invest / Grow
Selective
Medium Attractiveness
Invest / Grow
Selective
Harvest
Low Attractiveness
Selective
Harvest
Harvest / Divest Shattuck Labs Inc

Shattuck Labs Inc falls in the Low attractiveness / Low strength cell: Harvest / Divest.

Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.

Shattuck Labs Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

  • Outperforming the U.S.A. 500 over the trailing 12 months.

Weaknesses

  • Return on equity 60.8 points below the industry aggregate.
  • Low relative market share vs the industry leader (0.00x).

Opportunities

  • A meaningful share of tracked competitors (36.40 %) show financial-distress signals, a possible opening to gain share.

Threats

No rule matched.

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Shattuck Labs Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Shattuck Labs Inc 16.23 19.71 - 0.05
Novartis Ag 0.42 1.12 0.02 0.51
Astrazeneca Plc 0.19 0.94 0.51 0.51
Pfizer Inc 0.04 1.24 0.71 0.31
Vertex Pharmaceuticals Inc 1.34 2.85 - 0.48
Bristol myers Squibb Company 0.49 1.35 2.31 0.54
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Shattuck Labs Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Shattuck Labs Inc Q2 2026----
Novartis AgQ4 2025+9.6 %+9.6 %+17.0 %+17.0 %
Astrazeneca PlcQ4 2025+8.6 %+8.6 %+45.3 %+45.3 %
Pfizer IncQ2 2026+2.6 %+4.0 %--
Vertex Pharmaceuticals IncQ2 2026+12.5 %+11.6 %+6.5 %+6.6 %
Bristol myers Squibb CompanyQ2 2026+5.7 %+12.9 %+152.6 %+23.8 %
PEERS TOTAL+9.0 %+9.3 %+24.9 %+14.3 %
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Shattuck Labs Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Shattuck Labs Inc Q2 2026----
Novartis AgQ4 2025+18.3 %+18.3 %+13.3 %+13.3 %
Astrazeneca PlcQ4 2025+11.2 %+11.2 %+46.0 %+46.0 %
Pfizer IncQ2 2026+8.3 %+15.3 %-13.8 %+22.2 %
Vertex Pharmaceuticals IncQ2 2026+20.0 %+24.5 %-23.0 %-15.9 %
Bristol myers Squibb CompanyQ2 2026+10.5 %+8.9 %-15.5 %-12.1 %
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Shattuck Labs Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Shattuck Labs Inc -----
Novartis Ag12.59%12.62%30.00%6.34-
Astrazeneca Plc8.97%19.67%21.00%3.87-
Pfizer Inc2.12%2.53%4.91%4.981.60
Vertex Pharmaceuticals Inc16.88%19.97%23.31%6.191.03
Bristol myers Squibb Company10.27%13.58%46.65%4.605.37
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Shattuck Labs Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Shattuck Labs Inc -132.47-66.144.02
Novartis Ag20.375.0327.3424.866.12
Astrazeneca Plc25.094.370.3541.605.26
Pfizer Inc37.662.57--1.91
Vertex Pharmaceuticals Inc30.7110.68-114.686.64
Bristol myers Squibb Company13.842.620.20-5.77
PEERS AVERAGE29.354.5171.674.65
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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