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Protagenic Therapeutics Inc New's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Protagenic Therapeutics Inc New (PTIX) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q1 2026
Competitors
1
Named by the company
Peer Group Market Share
-
Share of combined sales, Q1 2026
Revenue Growth Y/Y
-
Peers: 12.91 %
Net Margin
-
Peers: 15.07 %

Key Findings: Protagenic Therapeutics Inc New vs Its Competitors

  • Scale: Protagenic Therapeutics Inc New ranks #461 of 545 companies by market capitalization in the Major Pharmaceutical Preparations industry, holding 0.0% of industry market cap.

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

API endpoints for this dataset

https://api.csimarket.com/api/v1/companies/PTIX/competitors
https://api.csimarket.com/api/v1/companies/PTIX/relationships
https://api.csimarket.com/api/v1/companies/PTIX/similar
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Protagenic Therapeutics Inc New's Competitor Quality Breadth

Group definitions: see Methodology: Performance Group Definitions.

Entity Profitable Expanding Above Industry Growth Distressed
Protagenic Therapeutics Inc new - - - Yes
Competitors combined (80) 57% 72% 56% 47%
Similar-Size Competitors (10) 0% 80% 40% 50%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

PTIX Stock Performance relative to its Competitors

PTIX Competitors (weighted) Percent change over the selected range

Protagenic Therapeutics Inc New's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
43.7%beat U.S.A. 500
Competitors Combined
(31 of 71)
16.7%beat U.S.A. 500
Similar-Size
(1 of 6)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Protagenic Therapeutics Inc new -74.80 % Underperformed
Competitors combined (71) 40.4% 63.2%
High-Confidence Competitors (0) 40.4% 63.2%
Similar-Size Competitors (6) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Protagenic Therapeutics Inc New's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

PTIX Stock Performance relative to Similar-Size Competitors

PTIX Similar-Size Competitors (equal-weighted, 10) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Ventyx Biosciences Inc 282.9% Outperformed
2 Climb Bio Inc 282.9% Outperformed
3 Gossamer Bio Inc 282.9% Outperformed
4 180 Life Sciences Corp 282.9% Outperformed
5 Dianthus Therapeutics Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Protagenic Therapeutics Inc New's best-performing competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Protagenic Therapeutics Inc New's Comment on Competition and Industry Peers

The pharmaceutical and biotechnology industries are characterized by intense competition, rapid technological advancements, and significant research and development efforts. The company anticipates competing with major international pharmaceutical firms and other organizations that possess greater financial resources, research and development capabilities, marketing and sales expertise, and experience in preclinical and clinical testing, regulatory approvals, and commercialization of biopharmaceutical products. Key competitive factors include product efficacy and safety, timing and scope of regulatory approvals, ease of use, and pricing. Despite a large patient population and opportunities for treatment improvement, the industry’s developmental pipelines are limited, with few novel candidates. Many pharmaceutical and small biotechnology companies have reduced or discontinued neuroscience research programs due to side effects and lack of efficacy. The company identifies competitive factors relevant to current drug classes for treatment-resistant depression (TRD) and suggests that its product, PT00114, may have competitive advantages based on preclinical animal studies; however, these advantages remain theoretical until validated by human clinical data. While opioid receptor modulators show potential for TRD, they are associated with a high risk of abuse and regulatory restrictions. PT00114 targets a different receptor system and is not expected to encounter these issues.

Publicly Traded Peers of Protagenic Therapeutics Inc new

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Protagenic Therapeutics Inc new 0.98 - 5.46 6
Eli Lilly And Company 1,209,663.60 86,462.00 27,579.70 50,000
Johnson and Johnson 676,352.29 99,335.00 16,095.00 140,800
Abbvie Inc 516,201.32 66,014.00 10,346.00 57,000
Merck and Co Inc 362,398.40 66,569.00 3,170.00 75,000
Novartis Ag 317,785.25 56,674.00 13,967.00 75,267
SUBTOTAL 4,038,616.81 636,327.20 102,362.85 658,266
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Sources: see Methodology: Peer & Competitor Identification, Sourcing.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Protagenic Therapeutics Inc new versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Protagenic Therapeutics Inc New's Competitors Named by the Company

Competitive relationships identified from Protagenic Therapeutics Inc New reports and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Sage Therapeutics Inc Company report 85% 2022 to 2026 3
Competitor Evidence Detail

Company report basis, confidence, active dates and source counts for Protagenic Therapeutics Inc New's named competitors require a Commercial License.

Methodology: see Methodology: Peer & Competitor Identification, Sourcing.

Protagenic Therapeutics Inc New's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Eli Lilly And Company Reportable 100.00 % - -
Johnson and Johnson Oncology 29.93 % Immunology 16.62 % Surgery 9.95 %
Merck and Co Inc Pharmaceutical segment 89.95 % Animal Health segment 9.27 % Corporate and Unallocated 0.78 %
Abbott Laboratories Diabetes Care 16.79 % Core Laboratory 11.05 % Adult Nutritionals 9.21 %
Pfizer Inc U.S. Commercial Division 58.35 % International Commercial Division 32.76 % Global Hospital and Biosimilars Division 7.07 %

Source: operating segment revenue as reported in each company's reports (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Protagenic Therapeutics Inc New's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Protagenic Therapeutics Inc new 1 - 910,314
Eli Lilly And Company 1,209,664 1,729,240 551,594
Johnson and Johnson 676,352 705,504 114,311
Abbvie Inc 516,201 1,158,140 181,509
Merck and Co Inc 362,398 887,587 42,267
Novartis Ag 317,785 752,973 185,566
PEERS TOTAL 4,038,616 966,681 155,497
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Protagenic Therapeutics Inc New's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent report. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Eli Lilly And Company United States 62.04 % Europe 18.28 % Rest of world 13.14 %
Johnson and Johnson United States 58.90 % Europe 21.28 % Asia-Pacific, Africa 14.37 %
Merck and Co Inc EMEA 21.50 % Latin America 5.42 % Asia Pacific 4.32 %
Abbott Laboratories Non-US 57.70 % - -
Pfizer Inc United States 63.93 % International Developed Markets 21.97 % International Emerging Markets 14.09 %

Source: revenue geography as reported in each company's reports (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

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Protagenic Therapeutics Inc New's Position in Industry Market Structure

Market-capitalization share and concentration across all 495 companies in Protagenic Therapeutics Inc New's industry classification, broader than the peer set above. Market cap in millions of $.

Protagenic Therapeutics Inc New ranks #461 of 495 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 875, indicating a unconcentrated market structure (see Methodology: Market Structure & Concentration).

Rank Company Market Cap Industry Share
1 Eli Lilly And Company 1,210,070 20.69 %
2 Johnson and Johnson 674,004 11.53 %
3 Beone Medicines Ltd 612,622 10.48 %
4 Abbvie Inc 515,910 8.82 %
5 Merck and Co Inc 1,234 5.2%
6 Novartis Ag 1,234 5.2%
7 Abbott Laboratories 1,234 5.2%
8 Novo Nordisk A 1,234 5.2%
9 Pfizer Inc 1,234 5.2%
10 Astrazeneca Plc 1,234 5.2%
461 Protagenic Therapeutics Inc new 1 0.00 %
Full Industry Market Structure

Market cap and industry share for the rest of Protagenic Therapeutics Inc New's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-11-06.

Protagenic Therapeutics Inc New's Same-Size Peers & Stock Performance

Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.
Rank Company Market Cap TTM Return 3M Momentum Beta Sharpe (1Y)
456 Avenue Therapeutics Inc 1 - - -0.36 0.62
457 Hcw Biologics Inc 1 -68.69 % -64.57 % -0.52 -21.00
458 Jupiter Neurosciences Inc 1 61.76 % -63.33 % -1.02 -26.73
459 International Stem Cell Corporation 1 - - 0.02 0.71
460 Genprex Inc 1,234 12.3% 4.5% 1.10 0.80
461 Protagenic Therapeutics Inc new 1 -74.77 % 50.00 % -0.33 0.27
462 Axim Biotechnologies Inc 1,234 12.3% 4.5% 1.10 0.80
463 Evofem Biosciences Inc 1,234 12.3% 4.5% 1.10 0.80
464 Skinvisible Inc 1,234 12.3% 4.5% 1.10 0.80
465 Pmgc Holdings Inc 1,234 12.3% 4.5% 1.10 0.80
466 The Greater Cannabis Company Inc 1,234 12.3% 4.5% 1.10 0.80
Full Same-Size Peer Performance

Market cap, return, momentum, beta and Sharpe ratio for the rest of Protagenic Therapeutics Inc New's same-size peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-11-06. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.

Protagenic Therapeutics Inc New's Valuation vs Competitive Position

Valuation multiples vs the Major Pharmaceutical Preparations industry average (444 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.
Metric Company Industry Average Difference
P/E 0.3x 26.6x -26.4x
EV / EBITDA 0.2x 15.9x -15.7x
P/B -1.5x 4.3x -5.8x
Return on Equity - industry aggregate -
Return on Invested Capital - -9.82 % (avg) -

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Protagenic Therapeutics Inc New's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in company reports.
Metric 20182019202020212022202320242025
Revenue Growth --------
Operating Margin --------
Return on Invested Capital -282.74 %-386.76 %-27.01 %-22.42 %-46.08 %--
P/E --------

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Protagenic Therapeutics Inc New's BCG Growth-Share Matrix

See Methodology: BCG Growth-Share Matrix for how relative share and growth are calculated and thresholded.

Question Mark Star Dog Cash Cow Relative Market Share (vs largest competitor) Industry Revenue Growth (%) Protagenic Therapeutics Inc New

Protagenic Therapeutics Inc New falls in the Dog quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 8.1% (median, trailing 12 months).

Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.

Protagenic Therapeutics Inc New's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 875 (see Industry Market Structure & Concentration above)

Note: see Methodology: Porter's Five Forces. Supplier power and buyer power are covered on Protagenic Therapeutics Inc New's dedicated Suppliers and Customers pages, not here.

Protagenic Therapeutics Inc New's Industry Attractiveness & Competitive Strength

See Methodology: GE/McKinsey Matrix for how the two axes are built.

High Strength
Medium Strength
Low Strength
High Attractiveness
Invest / Grow
Invest / Grow
Selective
Medium Attractiveness
Invest / Grow
Selective
Harvest
Low Attractiveness
Selective
Harvest
Harvest / Divest Protagenic Therapeutics Inc New

Protagenic Therapeutics Inc New falls in the Low attractiveness / Low strength cell: Harvest / Divest.

Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.

Protagenic Therapeutics Inc New's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

No rule matched.

Weaknesses

  • Underperforming the U.S.A. 500 over the trailing 12 months.
  • Low relative market share vs the industry leader (0.00x).
  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

  • A meaningful share of competitors (46.80 %) show financial-distress signals, a possible opening to gain share.

Threats

No rule matched.

Methodology: see Methodology: SWOT Analysis.

Protagenic Therapeutics Inc New's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Protagenic Therapeutics Inc new 0.35 0.40 - -
Eli Lilly And Company 0.16 1.44 1.44 0.67
Johnson and Johnson 0.36 1.04 0.60 0.50
Abbvie Inc 0.19 0.79 - 0.48
Merck and Co Inc 0.40 1.46 1.01 0.51
Novartis Ag 0.42 1.12 0.02 0.51
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Protagenic Therapeutics Inc New's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Protagenic Therapeutics Inc newQ2 2026----
Eli Lilly And CompanyQ3 2026+38.6 %+6.2 %+15.6 %-9.1 %
Johnson and JohnsonQ3 2026+5.9 %+0.4 %-95.9 %-96.2 %
Abbvie Inc Q3 2026+10.3 %+2.4 %+2,143.6 %+16.6 %
Merck and Co Inc Q2 2026+5.1 %+2.0 %--
Novartis AgQ4 2025+9.6 %+9.6 %+17.0 %+17.0 %
PEERS TOTAL+11.9 %+7.5 %-5.3 %+10.0 %
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Protagenic Therapeutics Inc New's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Protagenic Therapeutics Inc newQ2 2026----
Eli Lilly And CompanyQ3 2026+30.7 %+20.3 %+52.2 %+8.4 %
Johnson and JohnsonQ3 2026+10.9 %+0.6 %+17.7 %+3.1 %
Abbvie Inc Q3 2026-19.2 %-0.1 %-21.0 %-6.5 %
Merck and Co Inc Q2 2026+23.6 %+4.8 %+16.9 %-9.9 %
Novartis AgQ4 2025+18.3 %+18.3 %+13.3 %+13.3 %
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Protagenic Therapeutics Inc New's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Protagenic Therapeutics Inc new137.58%----
Eli Lilly And Company21.24%32.00%83.65%4.410.89
Johnson and Johnson8.06%10.53%19.55%5.452.17
Abbvie Inc 7.48%12.87%-5.043.40
Merck and Co Inc 2.42%3.24%6.59%5.472.79
Novartis Ag12.59%12.62%30.00%6.34-
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Protagenic Therapeutics Inc New's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Protagenic Therapeutics Inc new0.23---0.57
Eli Lilly And Company43.9613.990.29-30.04
Johnson and Johnson41.796.81--8.30
Abbvie Inc 50.147.820.34100.33-
Merck and Co Inc 118.325.44--8.63
Novartis Ag22.735.6130.5027.736.83
PEERS AVERAGE39.456.35301.947.35
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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