Vaxcyte Inc's Competitiveness
A competitive positioning analysis and financial ratio benchmarking of Vaxcyte Inc (PCVX) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.
Key Findings: Vaxcyte Inc vs Its Competitors
- Scale: Vaxcyte Inc ranks #17 of 165 companies by market capitalization in the Biotechnology & Pharmaceuticals industry, holding 0.9% of industry market cap.
Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).
Vaxcyte Inc's Competitor Quality Breadth
Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).
| Entity | Profitable | Expanding | Above Industry Growth | Distressed |
|---|---|---|---|---|
| Vaxcyte Inc | - | - | - | - |
| Competitors combined (27) | ||||
| High-Confidence Competitors (6) | ||||
| Similar-Size Competitors (10) |
Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.
PCVX Stock Performance relative to its Competitors
PCVX Stock Performance relative to High-Confidence Competitors
PCVX Stock Performance relative to Similar-Size Competitors
5 Best-Performing Tracked Competitors, Trailing 12 Months
| # | Competitor | TTM Share Price Return | vs U.S.A. 500 |
|---|---|---|---|
| 1 | Moderna Inc | 282.9% | Outperformed |
| 2 | Immunitybio inc | 282.9% | Outperformed |
| 3 | Merck and Co Inc | 282.9% | Outperformed |
| 4 | Tourmaline Bio Inc | 282.9% | Outperformed |
| 5 | Sutro Biopharma Inc | 282.9% | Outperformed |
TTM share price return and U.S.A. 500 outperformance for Vaxcyte Inc's best-performing tracked competitors requires a Commercial License.
Source: CSIMarket API, trailing 12 months.
Vaxcyte Inc's Comment on Competition and Industry Peers
Publicly Traded Peers of Vaxcyte Inc
Revenue and income for trailing 12 months, in millions of $, except employees| Company | Market Cap | Revenues |
|---|---|---|
| Vaxcyte Inc | 8,221.71 | - |
| Merck and Co Inc | 359,088.60 | 66,569.00 |
| Pfizer Inc | 162,592.47 | 63,696.00 |
| Sanofi | 101,062.98 | 49,307.90 |
| Gsk Plc | 99,157.95 | 43,093.89 |
| Moderna Inc | 76,642.86 | 2,228.00 |
| SUBTOTAL | 857,798.70 | 229,161.40 |
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Sources: Vaxcyte Inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Vaxcyte Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.
Vaxcyte Inc's Competitors Named by the Company
Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.| Competitor | Basis | Confidence |
|---|---|---|
| Moderna | Named by the company | 85% |
| GSK Vaccines Institute for Global Health | Named by the company | 85% |
| Sutro Biopharma | Named by the company | 85% |
| Cortexyme | Named by the company | 85% |
| Pfizer | Named by the company | 85% |
| Merck | Named by the company | 85% |
| GSK | Named by the company | 85% |
| Sanofi | Named by the company | 85% |
| Biontech Se | Named by the company | 85% |
Filing basis, confidence, active dates and source counts for Vaxcyte Inc's named competitors require a Commercial License.
Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.
Vaxcyte Inc's Business Segment Mix vs Peers
Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).| Company | Largest Segment |
|---|---|
| Merck and Co Inc | Pharmaceutical segment 88.88 % |
| Pfizer Inc | U.S. Commercial Division 52.92 % |
| Immunitybio inc | Reportable 100.00 % |
| Novavax inc | Reportable 100.00 % |
| Armata Pharmaceuticals Inc | Single Reportable Segment 100.00 % |
Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).
Vaxcyte Inc's Productivity vs Peers Comparison
Revenue and income per employee, trailing 12 months, in $; market cap in millions of $| Company | Market Cap | Revenue / Employee | Income / Employee |
|---|---|---|---|
| Vaxcyte Inc | 8,222 | - | -2,099,134 |
| Merck and Co Inc | 359,089 | 887,587 | 42,267 |
| Pfizer Inc | 162,592 | 849,280 | 58,267 |
| Sanofi | 101,063 | 21,607,316 | 3,889,794 |
| Gsk Plc | 99,158 | 169,660,977 | 32,662,867 |
| Moderna Inc | 76,643 | 474,043 | -670,426 |
| PEERS TOTAL | 849,577 | 1,361,843 | 105,163 |
Vaxcyte Inc's Geographic Revenue Exposure vs Peers
Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.| Company | Largest Market |
|---|---|
| Merck and Co Inc | EMEA 23.60 % |
| Pfizer Inc | United States 58.91 % |
| Immunitybio inc | United States 98.99 % |
| Novavax inc | United States 68.88 % |
Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.
Vaxcyte Inc's Position in Industry Market Structure
Market-capitalization share and concentration across all 159 companies in Vaxcyte Inc's industry classification, broader than the peer set above. Market cap in millions of $.Vaxcyte Inc ranks #17 of 159 companies by market capitalization in its industry, holding 0.93 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 1,326, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).
| Rank | Company | Market Cap | Industry Share |
|---|---|---|---|
| 1 | Amgen Inc | 231,632 | 26.18 % |
| 2 | Gilead Sciences Inc | 186,444 | 21.08 % |
| 3 | Moderna Inc | 78,102 | 8.83 % |
| 4 | Argenx Se | 63,011 | 7.12 % |
| 5 | Revolution Medicines Inc | 1,234 | 5.2% |
| 6 | Biogen Inc | 1,234 | 5.2% |
| 7 | Biontech Se | 1,234 | 5.2% |
| 8 | Exelixis Inc | 1,234 | 5.2% |
| 9 | Neurocrine Biosciences Inc | 1,234 | 5.2% |
| 10 | Halozyme Therapeutics Inc | 1,234 | 5.2% |
| 17 | Vaxcyte Inc | 8,207 | 0.93 % |
Market cap and industry share for the rest of Vaxcyte Inc's industry peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-30.
Vaxcyte Inc's Same-Size Peers & Stock Performance
Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.| Rank | Company | Market Cap | TTM Return |
|---|---|---|---|
| 12 | Repligen Corp | 11,030 | 56.94 % |
| 13 | Kymera Therapeutics Inc | 10,726 | 114.76 % |
| 14 | Krystal Biotech Inc | 10,246 | 89.09 % |
| 15 | Qiagen N v | 9,740 | 1.27 % |
| 16 | Immunitybio inc | 1,234 | 12.3% |
| 17 | Vaxcyte Inc | 8,207 | 63.92 % |
| 18 | Immunovant Inc | 1,234 | 12.3% |
| 19 | Iovance Biotherapeutics inc | 1,234 | 12.3% |
| 20 | Scholar Rock Holding Corp | 1,234 | 12.3% |
| 21 | Cg Oncology Inc | 1,234 | 12.3% |
| 22 | Kodiak Sciences Inc | 1,234 | 12.3% |
Market cap, return, momentum, beta and Sharpe ratio for the rest of Vaxcyte Inc's same-size peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-09-30. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.
Vaxcyte Inc's Valuation vs Competitive Position
Valuation multiples vs the Biotechnology & Pharmaceuticals industry average (93 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Biotechnology & Pharmaceuticals industry valuation benchmarks.| Metric | Company | Industry Average | Difference |
|---|---|---|---|
| P/E | - | 26.7x | - |
| EV / EBITDA | - | 21.3x | - |
| P/B | 2.7x | 5.1x | -2.4x |
| Return on Equity | -37.57 % | industry aggregate | -34.14 % |
| Return on Invested Capital | -21.05 % | -6.17 % (avg) | -14.88 % |
Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.
Vaxcyte Inc's Multi-Year Financial Trajectory
Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.| Metric | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|
| Revenue Growth | - | - | - | - | - | - |
| Operating Margin | - | - | - | - | - | - |
| Return on Invested Capital | - | -16.72 % | -22.47 % | -18.55 % | -10.59 % | -16.35 % |
| P/E | - | - | - | - | - | - |
Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.
Vaxcyte Inc's BCG Growth-Share Matrix
Relative market share (vs Vaxcyte Inc's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.
Vaxcyte Inc falls in the Question Mark quadrant: relative market share of 0.04x vs its largest competitor, in an industry growing revenue 10.0% (median, trailing 12 months).
Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.
Vaxcyte Inc's Competitive Forces (Porter's Five Forces)
Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.| Force | Assessment | Basis |
|---|---|---|
| Competitive Rivalry | High | Industry HHI of 1,326 (see Industry Market Structure & Concentration above) |
| Supplier Power | Not covered on this page | See Vaxcyte Inc's dedicated suppliers page for concentration and dependency data |
| Buyer Power | Not covered on this page | See Vaxcyte Inc's dedicated customers page for concentration and dependency data |
| Threat of Substitutes | - | No systematic data source for cross-product substitution exists in this system; not estimated |
Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.
Vaxcyte Inc's Industry Attractiveness & Competitive Strength
A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.
Vaxcyte Inc falls in the Low attractiveness / Low strength cell: Harvest / Divest.
Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.
Vaxcyte Inc's SWOT
Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.Strengths
- Outperforming the U.S.A. 500 over the trailing 12 months.
Weaknesses
- Return on equity 34.1 points below the industry aggregate.
- Low relative market share vs the industry leader (0.04x).
Opportunities
- Industry revenue growing at a healthy 10.0% median pace.
- A meaningful share of tracked competitors (46.20 %) show financial-distress signals, a possible opening to gain share.
Threats
- Tracked peer group's revenue run-rate is broadly decelerating (-4.3% annualized).
Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.
Vaxcyte Inc's Financial Strength vs Peers Comparison
Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months| Company | Quick Ratio | Working Capital | Debt / Equity |
|---|---|---|---|
| Vaxcyte Inc | 0.98 | 7.36 | - |
| Merck and Co Inc | 0.40 | 1.46 | 1.01 |
| Pfizer Inc | 0.04 | 1.24 | 0.71 |
| Sanofi | 0.27 | 1.09 | 0.20 |
| Gsk Plc | 0.16 | 0.82 | 0.87 |
| Moderna Inc | 0.86 | 2.88 | 0.07 |
Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.
Vaxcyte Inc's Revenue and Income Growth vs Peers
Quarterly revenue and net income growth, year over year and quarter over quarter| Company | Period | Revenue Y/Y | Income Y/Y |
|---|---|---|---|
| Vaxcyte Inc | Q2 2026 | - | - |
| Merck and Co Inc | Q2 2026 | +5.1 % | - |
| Pfizer Inc | Q2 2026 | +2.6 % | - |
| Sanofi | Q4 2025 | +10.9 % | +46.0 % |
| Gsk Plc | Q4 2025 | +7.5 % | +120.0 % |
| Moderna Inc | Q2 2026 | +2.1 % | - |
| PEERS TOTAL | +7.7 % | -17.4 % |
Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.
Vaxcyte Inc's Peers' Costs of Sales and Capital Expenditures
Context for revenue growth: peer costs and capex, year over year and quarter over quarter| Company | Period | Costs Y/Y | Capex Y/Y |
|---|---|---|---|
| Vaxcyte Inc | Q2 2026 | - | +138.5 % |
| Merck and Co Inc | Q2 2026 | +23.6 % | +16.9 % |
| Pfizer Inc | Q2 2026 | +8.3 % | -13.8 % |
| Sanofi | Q4 2025 | +9.3 % | - |
| Gsk Plc | Q4 2025 | +7.2 % | -0.6 % |
| Moderna Inc | Q2 2026 | -21.8 % | +1,133.3 % |
Vaxcyte Inc's Returns and Turnover vs Peers
ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover| Company | ROA | ROI | ROE |
|---|---|---|---|
| Vaxcyte Inc | - | - | - |
| Merck and Co Inc | 2.42% | 3.24% | 6.59% |
| Pfizer Inc | 2.12% | 2.53% | 4.91% |
| Sanofi | 5.96% | 8.19% | 10.55% |
| Gsk Plc | 10.09% | 44.94% | 38.67% |
| Moderna Inc | - | - | - |
ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).
Vaxcyte Inc's Valuation vs Peers
P/E, price to sales, PEG, price to cash flow and price to book| Company | P/E | Price / Sales |
|---|---|---|
| Vaxcyte Inc | - | - |
| Merck and Co Inc | 117.24 | 5.39 |
| Pfizer Inc | 37.41 | 2.55 |
| Sanofi | 11.44 | 2.05 |
| Gsk Plc | 17.35 | 2.30 |
| Moderna Inc | - | 34.40 |
| PEERS AVERAGE | 51.58 | 3.74 |
P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.