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Panbela Therapeutics Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Panbela Therapeutics Inc (PBLA) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q3 2024
Competitors Tracked
90
Publicly traded peers
Peer Group Market Share
-
Share of combined sales, Q3 2024
Revenue Growth Y/Y
-
Peers: 18.28 %
Net Margin
-
Peers: 15.10 %
API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/PBLA/competitors
https://api.csimarket.com/api/v1/companies/PBLA/relationships
https://api.csimarket.com/api/v1/companies/PBLA/similar
Programmatic access for models, analytics, and integration workflows.

Panbela Therapeutics Inc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Panbela Therapeutics Inc - - - Yes
Competitors combined (87) 31% 75% 61% 48%
High-Confidence Competitors (1) - - - 0%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

PBLA Stock Performance relative to its Competitors

PBLA Competitors (weighted) Percent change over the selected range

Panbela Therapeutics Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
50%beat U.S.A. 500
Competitors Combined
(35 of 70)
0%beat U.S.A. 500
High-Confidence
(0 of 1)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Panbela Therapeutics Inc - -
Competitors combined (70) 40.4% 63.2%
High-Confidence Competitors (1) 40.4% 63.2%
Similar-Size Competitors (0) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Panbela Therapeutics Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

PBLA Stock Performance relative to High-Confidence Competitors

PBLA High-Confidence Competitors (equal-weighted, 1) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Adlai Nortye Ltd 282.9% Outperformed
2 Erasca Inc 282.9% Outperformed
3 Iovance Biotherapeutics inc 282.9% Outperformed
4 Spyre Therapeutics Inc 282.9% Outperformed
5 Gossamer Bio Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Panbela Therapeutics Inc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Panbela Therapeutics Inc's Comment on Competition and Industry Peers

The company operates in a competitive environment focused on the development and commercialization of new cancer treatments. It faces competition from major pharmaceutical companies, specialty pharmaceutical companies, and biotechnology firms globally. Competitors often possess greater financial, technical, and human resources. Smaller and early-stage companies may also be significant competitors, particularly through collaborations with larger firms. Competitors may develop, license, or commercialize products before or more successfully than the company, potentially securing regulatory approvals or intellectual property rights that could restrict the company's ability to develop or commercialize its products. Competition exists for both current and future product candidates, especially from companies targeting molecular alterations and signaling pathways associated with cancer.

Publicly Traded Peers of Panbela Therapeutics Inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Panbela Therapeutics Inc 0.05 - -27.92 26
Eli Lilly And Company 1,058,703.83 79,665.80 26,711.20 50,000
Novartis Ag 284,863.05 56,674.00 13,967.00 75,267
Astrazeneca Plc 256,496.02 58,739.00 10,233.00 83,100
Amgen Inc 230,460.16 38,095.00 8,743.00 13,000
Pfizer Inc 163,675.28 63,696.00 4,370.00 75,000
SUBTOTAL 2,413,622.43 396,513.95 71,324.64 420,366
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Sources: Panbela Therapeutics Inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Panbela Therapeutics Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Panbela Therapeutics Inc's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Biodexa Pharmaceuticals Plc Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for Panbela Therapeutics Inc's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

Panbela Therapeutics Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Eli Lilly And Company Reportable 100.00 % - -
Amgen Inc Reportable 100.00 % - -
Pfizer Inc U.S. Commercial Division 52.92 % International Commercial Division 36.88 % Global Hospital and Biosimilars Division 7.72 %
Teva Pharmaceutical Industries Limited United States Segment 41.09 % Europe Segment 30.49 % Other activities 15.14 %
Viatris Inc Developed Markets 57.61 % Greater China 19.34 % Emerging Markets 15.28 %

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Panbela Therapeutics Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Panbela Therapeutics Inc 0 - -1,073,731
Eli Lilly And Company 1,058,704 1,593,316 534,224
Novartis Ag 284,863 752,973 185,566
Astrazeneca Plc 256,496 706,847 123,141
Amgen Inc 230,460 2,930,385 672,538
Pfizer Inc 163,675 849,280 58,267
PEERS TOTAL 2,413,622 943,317 169,750
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Panbela Therapeutics Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Eli Lilly And Company United States 61.21 % Europe 18.42 % Rest of world 14.00 %
Pfizer Inc United States 58.91 % International Developed Markets 24.90 % International Emerging Markets 16.19 %
Bristol myers Squibb Company United States 67.79 % Non-US 29.98 % Other Region 2.24 %
Teva Pharmaceutical Industries Limited Europe 30.49 % - -
Hutchmed china Limited CN 74.28 % United States and Others 25.72 % -

Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

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Panbela Therapeutics Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 498 companies in Panbela Therapeutics Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Panbela Therapeutics Inc ranks #0 of 498 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 824, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Eli Lilly And Company 1,058,704 19.37 %
2 Johnson and Johnson 652,898 11.95 %
3 Beone Medicines Ltd 549,864 10.06 %
4 Abbvie Inc 466,251 8.53 %
5 Merck and Co Inc 1,234 5.2%
6 Novartis Ag 1,234 5.2%
7 Abbott Laboratories 1,234 5.2%
8 Novo Nordisk A 1,234 5.2%
9 Pfizer Inc 1,234 5.2%
10 Vertex Pharmaceuticals Inc 1,234 5.2%
0 Panbela Therapeutics Inc 0 0.00 %
Full Industry Market Structure

Market cap and industry share for the rest of Panbela Therapeutics Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-28.

Panbela Therapeutics Inc's Valuation vs Competitive Position

Valuation multiples vs the Major Pharmaceutical Preparations industry average (342 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 25.1x -
EV / EBITDA - 17.3x -
P/B -0.2x 4.5x -4.7x
Return on Equity 304.84 % industry aggregate 294.50 %
Return on Invested Capital 198.73 % -2.95 % (avg) 201.68 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Panbela Therapeutics Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 20152016201720192020202120222023
Revenue Growth --------
Operating Margin --------
Return on Invested Capital 490.47 %106.52 %238.75 %-226.82 %-56.63 %-53.87 %1,083.35 %-567.91 %
P/E --------

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Panbela Therapeutics Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 824 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Panbela Therapeutics Inc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Panbela Therapeutics Inc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Panbela Therapeutics Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

  • Return on equity 294.5 points above the industry aggregate.

Weaknesses

  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

  • A meaningful share of tracked competitors (48.10 %) show financial-distress signals, a possible opening to gain share.

Threats

  • Tracked peer group's revenue run-rate is broadly decelerating (-37.1% annualized).

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Panbela Therapeutics Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Panbela Therapeutics Inc 0.05 0.18 - -
Eli Lilly And Company 0.20 1.48 1.59 0.66
Novartis Ag 0.42 1.12 0.02 0.51
Astrazeneca Plc 0.19 0.94 0.51 0.51
Amgen Inc 0.46 1.26 5.86 0.41
Pfizer Inc 0.04 1.24 0.71 0.31
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Panbela Therapeutics Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Panbela Therapeutics Inc Q3 2024----
Eli Lilly And CompanyQ2 2026+47.7 %+16.0 %+25.3 %-4.1 %
Novartis AgQ4 2025+9.6 %+9.6 %+17.0 %+17.0 %
Astrazeneca PlcQ4 2025+8.6 %+8.6 %+45.3 %+45.3 %
Amgen Inc Q2 2026+9.5 %+16.7 %+65.9 %+30.6 %
Pfizer IncQ2 2026+2.6 %+4.0 %--
PEERS TOTAL+11.9 %+10.2 %+21.1 %+11.3 %
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Panbela Therapeutics Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Panbela Therapeutics Inc Q3 2024----
Eli Lilly And CompanyQ2 2026+33.5 %-8.6 %+72.8 %+26.1 %
Novartis AgQ4 2025+18.3 %+18.3 %+13.3 %+13.3 %
Astrazeneca PlcQ4 2025+11.2 %+11.2 %+46.0 %+46.0 %
Amgen Inc Q2 2026-6.6 %+2.4 %+39.0 %-27.9 %
Pfizer IncQ2 2026+8.3 %+15.3 %-13.8 %+22.2 %
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Panbela Therapeutics Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Panbela Therapeutics Inc -----
Eli Lilly And Company21.97%33.95%92.54%4.400.92
Novartis Ag12.59%12.62%30.00%6.34-
Astrazeneca Plc8.97%19.67%21.00%3.87-
Amgen Inc 9.48%13.08%89.32%4.071.86
Pfizer Inc2.12%2.53%4.91%4.981.60
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Panbela Therapeutics Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Panbela Therapeutics Inc -----
Eli Lilly And Company39.7713.290.28189.9231.25
Novartis Ag20.375.0327.3424.866.12
Astrazeneca Plc25.094.370.3541.605.26
Amgen Inc 26.316.050.5638.6619.72
Pfizer Inc37.662.57--1.91
PEERS AVERAGE33.846.0992.147.59
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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