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Passage Bio Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Passage Bio Inc (PASG) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q2 2026
Competitors Tracked
16
Publicly traded peers
Peer Group Market Share
-
Share of combined sales, Q2 2026
Revenue Growth Y/Y
-
Peers: 154.06 %
Net Margin
-
Peers: -515.78 %

Key Findings: Passage Bio Inc vs Its Competitors

  • Scale: Passage Bio Inc ranks #135 of 165 companies by market capitalization in the Biotechnology & Pharmaceuticals industry, holding 0.0% of industry market cap.

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/PASG/competitors
https://api.csimarket.com/api/v1/companies/PASG/relationships
https://api.csimarket.com/api/v1/companies/PASG/similar
Programmatic access for models, analytics, and integration workflows.

Passage Bio Inc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Passage Bio Inc - - - Yes
Competitors combined (16) 36% 55% 36% 15%
High-Confidence Competitors (15) 40% 60% 40% 33%
Similar-Size Competitors (10) 0% 0% 0% 60%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

PASG Stock Performance relative to its Competitors

PASG Competitors (weighted) Percent change over the selected range

Passage Bio Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
53.3%beat U.S.A. 500
Competitors Combined
(8 of 15)
60%beat U.S.A. 500
High-Confidence
(6 of 10)
0%beat U.S.A. 500
Similar-Size
(0 of 8)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Passage Bio Inc -39.00 % Underperformed
Competitors combined (15) 40.4% 63.2%
High-Confidence Competitors (10) 40.4% 63.2%
Similar-Size Competitors (8) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Passage Bio Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

PASG Stock Performance relative to High-Confidence Competitors

PASG High-Confidence Competitors (equal-weighted, 16) Percent change over the selected range

PASG Stock Performance relative to Similar-Size Competitors

PASG Similar-Size Competitors (equal-weighted, 10) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Contextlogic Inc 282.9% Outperformed
2 4d Molecular Therapeutics Inc 282.9% Outperformed
3 Taysha Gene Therapies Inc 282.9% Outperformed
4 Denali Therapeutics Inc 282.9% Outperformed
5 Protalix Biotherapeutics inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Passage Bio Inc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Passage Bio Inc's Comment on Competition and Industry Peers

The company operates in the biotechnology and pharmaceutical sectors, focusing on gene therapies and genetic medicine. Its primary competitor for the treatment of frontotemporal dementia linked to progranulin mutations (FTD-GRN) is AviadoBio Ltd, which initiated a Phase 1/2 gene therapy trial in 2023 and holds an exclusive option and licensing agreement with Astellas Pharma Inc. Additional entities engaged in preclinical research for FTD-GRN include Kyowa Kirin Co., Ltd. and QurAlis Corporation. Denali Therapeutics Inc., in collaboration with Takeda Pharmaceutical Company Limited, is conducting a Phase 1/2 clinical trial involving recombinant progranulin protein. In the area of Huntington's Disease (HD), Evox Therapeutics Ltd, Latus Bio, Inc., uniQure N.V., and Voyager Therapeutics, Inc. are developing preclinical gene therapy programs targeting the DNA repair protein MSH3. Other companies are investigating alternative methods to target MSH3 and other DNA repair proteins such as FAN1. Several competitors possess greater resources and may develop products with improved safety, efficacy, or convenience, which could affect the company's commercial prospects.

Publicly Traded Peers of Passage Bio Inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Passage Bio Inc 14.86 - -36.11 27
Gsk Plc 101,586.98 32,667.00 6,289.00 254
Takeda Pharmaceutical Company Limited 29,714.53 29,183.90 688.86 47,000
Crispr Therapeutics Ag 5,404.79 13.39 -451.14 201
Denali Therapeutics Inc 3,898.01 110.69 0.99 503
Taysha Gene Therapies Inc 1,841.53 8.10 -149.63 99
SUBTOTAL 147,928.01 62,438.15 5,311.96 49,983
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Sources: Passage Bio Inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Passage Bio Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Passage Bio Inc's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
uniQure N.V. Named by the company 85% 2022 to 2026 3
Takeda Pharmaceutical Company Limited Named by the company 85% 2022 to 2026 3
Denali Therapeutics Named by the company 85% 2022 to 2026 3
Alector, Inc. Named by the company 85% 2022 to 2026 3
Prevail Therapeutics Inc. Named by the company 85% 2022 to 2026 3
GlaxoSmithKline Named by the company 85% 2022 to 2026 3
AcuraStem Inc. Named by the company 85% 2022 to 2026 3
Astellas Named by the company 85% 2022 to 2026 3
Evox Therapeutics Ltd Named by the company 85% 2022 to 2026 3
Lysogene, S.A. Named by the company 85% 2022 to 2026 3
QurAlis Corporation Named by the company 85% 2022 to 2026 3
Applied Genetic Technologies Corporation Named by the company 85% 2022 to 2026 3
Kyowa Kirin Co., Ltd. Named by the company 85% 2022 to 2026 3
Orchard Therapeutics plc Named by the company 85% 2022 to 2026 3
Sio Gene Therapies, Inc. Named by the company 85% 2022 to 2026 3
Voyager Therapeutics, Inc. Named by the company 85% 2022 to 2026 3
Astellas Pharma Inc. Named by the company 85% 2022 to 2026 3
Forge Biologics Inc. Named by the company 85% 2022 to 2026 3
National Institutes of Health Named by the company 85% 2022 to 2026 3
QurAlis Therapeutics Named by the company 85% 2022 to 2026 3
Transposon Therapeutics, Inc. Named by the company 85% 2022 to 2026 3
Crispr Therapeutics Ag Named by the company 85% 2022 to 2026 3
Arkuda Therapeutics, Inc. Named by the company 85% 2022 to 2026 3
Eli Lilly & Co Named by the company 85% 2022 to 2026 3
Latus Bio, Inc. Named by the company 85% 2022 to 2026 3
Syncona Limited Named by the company 85% 2022 to 2026 3
Alkermes plc Named by the company 85% 2022 to 2026 3
AviadoBio Named by the company 85% 2022 to 2026 3
Neurogene Inc. Named by the company 85% 2022 to 2026 3
Shape Therapeutics Inc. Named by the company 85% 2022 to 2026 3
Medicines Co Named by the company 85% 2022 to 2026 3
Bluebird Bio Inc Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for Passage Bio Inc's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

Passage Bio Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Uniqure N v Single Reportable Segment 100.00 % - -
Editas Medicine Inc Reportable 100.00 % - -
Protalix Biotherapeutics inc Single Reportable Segment 100.00 % - -
Voyager Therapeutics Inc Single reportable segment 100.00 % - -
Sangamo Therapeutics Inc Reportable 100.00 % - -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

Passage Bio Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Passage Bio Inc 15 - -1,337,481
Gsk Plc 101,587 128,610,236 24,759,843
Takeda Pharmaceutical Company Limited 29,715 620,934 14,657
Crispr Therapeutics Ag 5,405 66,627 -2,244,473
Denali Therapeutics Inc 3,898 220,068 1,962
Taysha Gene Therapies Inc 1,842 81,798 -1,511,444
PEERS TOTAL 147,913 1,249,863 107,056
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Passage Bio Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
4d Molecular Therapeutics Inc JP 97.05 % US 2.95 % -

Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

Passage Bio Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 159 companies in Passage Bio Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Passage Bio Inc ranks #135 of 159 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 1,324, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Amgen Inc 230,460 25.95 %
2 Gilead Sciences Inc 188,041 21.17 %
3 Moderna Inc 80,977 9.12 %
4 Argenx Se 64,092 7.22 %
5 Revolution Medicines Inc 1,234 5.2%
6 Biogen Inc 1,234 5.2%
7 Biontech Se 1,234 5.2%
8 Exelixis Inc 1,234 5.2%
9 Neurocrine Biosciences Inc 1,234 5.2%
10 Halozyme Therapeutics Inc 1,234 5.2%
135 Passage Bio Inc 15 0.00 %
Full Industry Market Structure

Market cap and industry share for the rest of Passage Bio Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-29.

Passage Bio Inc's Same-Size Peers & Stock Performance

Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.
Rank Company Market Cap TTM Return 3M Momentum Beta Sharpe (1Y)
130 In8bio Inc 25 -44.10 % -11.10 % 1.00 -0.29
131 Cel sci Corporation 22 -80.84 % 35.02 % 1.04 -1.01
132 Tradeup Acquisition Corp 20 -60.17 % -53.92 % 0.37 -0.30
133 Jasper Therapeutics Inc 18 -73.77 % 39.06 % 1.37 -0.86
134 Dyadic International Inc 1,234 12.3% 4.5% 1.10 0.80
135 Passage Bio Inc 15 -39.00 % 3.83 % 1.89 0.05
136 Genenta Science S p a 1,234 12.3% 4.5% 1.10 0.80
137 Zivo Bioscience Inc 1,234 12.3% 4.5% 1.10 0.80
138 Biocardia Inc 1,234 12.3% 4.5% 1.10 0.80
139 Brainstorm Cell Therapeutics inc 1,234 12.3% 4.5% 1.10 0.80
140 Pluri Inc 1,234 12.3% 4.5% 1.10 0.80
Full Same-Size Peer Performance

Market cap, return, momentum, beta and Sharpe ratio for the rest of Passage Bio Inc's same-size peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-09-29. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.

Passage Bio Inc's Valuation vs Competitive Position

Valuation multiples vs the Biotechnology & Pharmaceuticals industry average (93 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Biotechnology & Pharmaceuticals industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 26.7x -
EV / EBITDA - 21.3x -
P/B 1.0x 5.1x -4.1x
Return on Equity -218.59 % industry aggregate -215.16 %
Return on Invested Capital -87.68 % -6.17 % (avg) -81.51 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Passage Bio Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 202020212022202320242025
Revenue Growth ------
Operating Margin ------
Return on Invested Capital -16.18 %-27.30 %-27.59 %-35.78 %-37.65 %-55.78 %
P/E ------

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Passage Bio Inc's BCG Growth-Share Matrix

Relative market share (vs Passage Bio Inc's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.

Question Mark Star Dog Cash Cow Relative Market Share (vs largest competitor) Industry Revenue Growth (%) Passage Bio Inc

Passage Bio Inc falls in the Question Mark quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 10.0% (median, trailing 12 months).

Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.

Passage Bio Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 1,324 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Passage Bio Inc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Passage Bio Inc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Passage Bio Inc's Industry Attractiveness & Competitive Strength

A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.

High Strength
Medium Strength
Low Strength
High Attractiveness
Invest / Grow
Invest / Grow
Selective
Medium Attractiveness
Invest / Grow
Selective
Harvest
Low Attractiveness
Selective
Harvest
Harvest / Divest Passage Bio Inc

Passage Bio Inc falls in the Low attractiveness / Low strength cell: Harvest / Divest.

Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.

Passage Bio Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

No rule matched.

Weaknesses

  • Return on equity 215.2 points below the industry aggregate.
  • Underperforming the U.S.A. 500 over the trailing 12 months.
  • Low relative market share vs the industry leader (0.00x).
  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

  • Industry revenue growing at a healthy 10.0% median pace.

Threats

  • Tracked peer group's revenue run-rate is broadly decelerating (-16.9% annualized).

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Passage Bio Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Passage Bio Inc 1.82 1.90 - -
Gsk Plc - - - 0.53
Takeda Pharmaceutical Company Limited 0.09 0.56 0.58 0.32
Crispr Therapeutics Ag 2.51 16.26 0.16 0.01
Denali Therapeutics Inc 2.28 9.16 - 0.10
Taysha Gene Therapies Inc 13.32 13.51 0.19 0.02
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Passage Bio Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Passage Bio Inc Q2 2026----
Gsk PlcQ4 2025+4.1 %+4.1 %+113.1 %+113.1 %
Takeda Pharmaceutical Company LimitedQ1 2025+0.1 %+0.1 %-30.2 %-30.2 %
Crispr Therapeutics AgQ2 2026+1,041.4 %+598.3 %--
Denali Therapeutics Inc Q2 2026----
Taysha Gene Therapies Inc Q2 2026----
PEERS TOTAL+2.3 %+2.2 %+105.9 %+86.8 %
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Passage Bio Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Passage Bio Inc Q2 2026----
Gsk PlcQ4 2025+2.9 %+2.9 %-0.6 %-0.6 %
Takeda Pharmaceutical Company LimitedQ1 2025+3.1 %+3.1 %+6.6 %+6.6 %
Crispr Therapeutics AgQ2 2026--+453.8 %+28.6 %
Denali Therapeutics Inc Q2 2026--+592.0 %+1,100.5 %
Taysha Gene Therapies Inc Q2 2026----
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Passage Bio Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Passage Bio Inc -----
Gsk Plc10.29%51.22%39.41%3.25-
Takeda Pharmaceutical Company Limited0.76%0.97%1.56%6.17-
Crispr Therapeutics Ag-----
Denali Therapeutics Inc 0.09%0.09%0.11%56.38-
Taysha Gene Therapies Inc -----
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Passage Bio Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Passage Bio Inc ----3.33
Gsk Plc17.773.11-22.676.37
Takeda Pharmaceutical Company Limited43.141.02-10.190.67
Crispr Therapeutics Ag-403.58-57.373.09
Denali Therapeutics Inc -35.21-64.624.67
Taysha Gene Therapies Inc -227.41-13.134.76
PEERS AVERAGE27.852.3720.452.27
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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