Nucana Plc's Competitiveness
A competitive positioning analysis and financial ratio benchmarking of Nucana Plc (NCNA) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.
Key Findings: Nucana Plc vs Its Competitors
- Scale: Nucana Plc ranks #429 of 543 companies by market capitalization in the Major Pharmaceutical Preparations industry, holding 0.0% of industry market cap.
Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).
API endpoints for this dataset
Nucana Plc's Competitor Quality Breadth
Group definitions: see Methodology: Performance Group Definitions.
| Entity | Profitable | Expanding | Above Industry Growth | Distressed |
|---|---|---|---|---|
| Nucana Plc | - | - | - | No |
| Competitors combined (44) | ||||
| Similar-Size Competitors (10) | - |
Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.
NCNA Stock Performance relative to its Competitors
NCNA Stock Performance relative to Similar-Size Competitors
5 Best-Performing Tracked Competitors, Trailing 12 Months
| # | Competitor | TTM Share Price Return | vs U.S.A. 500 |
|---|---|---|---|
| 1 | Gt Biopharma Inc | 282.9% | Outperformed |
| 2 | Spyre Therapeutics Inc | 282.9% | Outperformed |
| 3 | Iovance Biotherapeutics inc | 282.9% | Outperformed |
| 4 | Xencor Inc | 282.9% | Outperformed |
| 5 | Tg Therapeutics Inc | 282.9% | Outperformed |
TTM share price return and U.S.A. 500 outperformance for Nucana Plc's best-performing competitors requires a Commercial License.
Source: CSIMarket API, trailing 12 months.
Nucana Plc's Comment on Competition and Industry Peers
Publicly Traded Peers of Nucana Plc
Revenue and income for trailing 12 months, in millions of $, except employees| Company | Market Cap | Revenues |
|---|---|---|
 Nucana Plc |
2.77 | - |
 Incyte Corporation |
24,586.67 | 6,010.75 |
 Tg Therapeutics Inc |
10,146.25 | 799.54 |
 Protagonist Therapeutics inc |
9,298.37 | 281.99 |
 Iovance Biotherapeutics inc |
3,537.93 | 378.98 |
 Xencor Inc |
2,813.61 | 104.97 |
| SUBTOTAL | 65,245.55 | 8,983.18 |
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Sources: see Methodology: Peer & Competitor Identification, Sourcing.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Nucana Plc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.
Nucana Plc's Competitors Named by the Company
Competitive relationships identified from Nucana Plc reports and corroborating sources, each with a basis and confidence.| Competitor | Basis | Confidence |
|---|---|---|
| Mersana Therapeutics inc | Company report | 85% |
Company report basis, confidence, active dates and source counts for Nucana Plc's named competitors require a Commercial License.
Methodology: see Methodology: Peer & Competitor Identification, Sourcing.
Nucana Plc's Business Segment Mix vs Peers
Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).| Company | Largest Segment |
|---|---|
| Incyte Corporation | Reportable 100.00 % |
| Protagonist Therapeutics inc | Single reportable segment 100.00 % |
| Iovance Biotherapeutics inc | Single reportable segment 100.00 % |
| Xencor Inc | Reportable 100.00 % |
| Hutchmed china Limited | Other Ventures segment 47.94 % |
Source: operating segment revenue as reported in each company's reports (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).
Nucana Plc's Productivity vs Peers Comparison
Revenue and income per employee, trailing 12 months, in $; market cap in millions of $| Company | Market Cap | Revenue / Employee | Income / Employee |
|---|---|---|---|
| Nucana Plc | 3 | - | -3,226,842 |
| Incyte Corporation | 24,587 | 2,113,486 | 141,846 |
| Tg Therapeutics Inc | 10,146 | 2,003,850 | 1,106,491 |
| Protagonist Therapeutics inc | 9,298 | 2,136,303 | 616,273 |
| Iovance Biotherapeutics inc | 3,538 | 388,701 | -226,190 |
| Xencor Inc | 2,814 | 403,742 | -628,173 |
| PEERS TOTAL | 65,243 | 982,735 | -95,898 |
Nucana Plc's Geographic Revenue Exposure vs Peers
Revenue by country/region as reported in each company's most recent report. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.| Company | Largest Market |
|---|---|
| Incyte Corporation | United States 92.15 % |
| Iovance Biotherapeutics inc | US 98.66 % |
| Hutchmed china Limited | CN 74.28 % |
| Integrated Biopharma Inc | US 77.78 % |
Source: revenue geography as reported in each company's reports (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.
Nucana Plc's Position in Industry Market Structure
Market-capitalization share and concentration across all 490 companies in Nucana Plc's industry classification, broader than the peer set above. Market cap in millions of $.Nucana Plc ranks #429 of 490 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 999, indicating a unconcentrated market structure (see Methodology: Market Structure & Concentration).
| Rank | Company | Market Cap | Industry Share |
|---|---|---|---|
| 1 | Eli Lilly And Company | 1,290,056 | 24.11 % |
| 2 | Johnson and Johnson | 697,259 | 13.03 % |
| 3 | Abbvie Inc | 522,498 | 9.76 % |
| 4 | Merck and Co Inc | 364,967 | 6.82 % |
| 5 | Novartis Ag | 1,234 | 5.2% |
| 6 | Abbott Laboratories | 1,234 | 5.2% |
| 7 | Novo Nordisk A | 1,234 | 5.2% |
| 8 | Pfizer Inc | 1,234 | 5.2% |
| 9 | Astrazeneca Plc | 1,234 | 5.2% |
| 10 | Vertex Pharmaceuticals Inc | 1,234 | 5.2% |
| 429 | Nucana Plc | 3 | 0.00 % |
Market cap and industry share for the rest of Nucana Plc's industry peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-11-13.
Nucana Plc's Same-Size Peers & Stock Performance
Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.| Rank | Company | Market Cap | TTM Return |
|---|---|---|---|
| 424 | Bio Green Med Solution Inc | 4 | -50.01 % |
| 425 | Imunon Inc | 3 | -84.53 % |
| 426 | Gelteq Limited | 3 | - |
| 427 | Gri Bio Inc | 3 | -96.62 % |
| 428 | Mustang Bio inc | 1,234 | 12.3% |
| 429 | Nucana Plc | 3 | -75.46 % |
| 430 | Bioxytran Inc | 1,234 | 12.3% |
| 431 | Dermata Therapeutics Inc | 1,234 | 12.3% |
| 432 | Can fite Biopharma Ltd | 1,234 | 12.3% |
| 433 | Revelation Biosciences Inc | 1,234 | 12.3% |
| 434 | Moleculin Biotech Inc | 1,234 | 12.3% |
Market cap, return, momentum, beta and Sharpe ratio for the rest of Nucana Plc's same-size peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-11-13. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.
Nucana Plc's Valuation vs Competitive Position
Valuation multiples vs the Major Pharmaceutical Preparations industry average (447 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.| Metric | Company | Industry Average | Difference |
|---|---|---|---|
| P/E | - | 26.2x | - |
| EV / EBITDA | - | 15.2x | - |
| P/B | 0.4x | 4.2x | -3.9x |
| Return on Equity | -118.37 % | industry aggregate | -138.49 % |
| Return on Invested Capital | -37.41 % | -9.68 % (avg) | -27.73 % |
Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.
Nucana Plc's Multi-Year Financial Trajectory
Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in company reports.| Metric | 2023 | 2024 | 2025 |
|---|---|---|---|
| Revenue Growth | - | - | - |
| Operating Margin | - | - | - |
| Return on Invested Capital | -80.51 % | -123.44 % | -37.41 % |
| P/E | - | - | - |
Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.
Nucana Plc's BCG Growth-Share Matrix
See Methodology: BCG Growth-Share Matrix for how relative share and growth are calculated and thresholded.
Nucana Plc falls in the Dog quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 8.2% (median, trailing 12 months).
Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.
Nucana Plc's Competitive Forces (Porter's Five Forces)
Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.| Force | Assessment | Basis |
|---|---|---|
| Competitive Rivalry | High | Industry HHI of 999 (see Industry Market Structure & Concentration above) |
Note: see Methodology: Porter's Five Forces. Supplier power and buyer power are covered on Nucana Plc's dedicated Suppliers and Customers pages, not here.
Nucana Plc's Industry Attractiveness & Competitive Strength
See Methodology: GE/McKinsey Matrix for how the two axes are built.
Nucana Plc falls in the Low attractiveness / Low strength cell: Harvest / Divest.
Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.
Nucana Plc's SWOT
Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.Strengths
No rule matched.
Weaknesses
- Return on equity 138.5 points below the industry aggregate.
- Underperforming the U.S.A. 500 over the trailing 12 months.
- Low relative market share vs the industry leader (0.00x).
Opportunities
- A meaningful share of competitors (53.50 %) show financial-distress signals, a possible opening to gain share.
Threats
No rule matched.
Methodology: see Methodology: SWOT Analysis.
Nucana Plc's Financial Strength vs Peers Comparison
Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months| Company | Quick Ratio | Working Capital | Debt / Equity |
|---|---|---|---|
| Nucana Plc | 5.06 | 5.60 | - |
| Incyte Corporation | 2.40 | 3.83 | - |
| Tg Therapeutics Inc | 1.58 | 4.52 | 0.81 |
| Protagonist Therapeutics inc | 5.28 | 15.94 | - |
| Iovance Biotherapeutics inc | 1.10 | 4.00 | 0.00 |
| Xencor Inc | 0.42 | 6.29 | 0.20 |
Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.
Nucana Plc's Revenue and Income Growth vs Peers
Quarterly revenue and net income growth, year over year and quarter over quarter| Company | Period | Revenue Y/Y | Income Y/Y |
|---|---|---|---|
| Nucana Plc | Q4 2025 | - | - |
| Incyte Corporation | Q3 2026 | +14.0 % | - |
| Tg Therapeutics Inc | Q2 2026 | +70.3 % | -72.4 % |
| Protagonist Therapeutics inc | Q2 2026 | +3,749.2 % | - |
| Iovance Biotherapeutics inc | Q3 2026 | +80.1 % | - |
| Xencor Inc | Q2 2026 | +17.5 % | - |
| PEERS TOTAL | +17.5 % | - |
Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.
Nucana Plc's Peers' Costs of Sales and Capital Expenditures
Context for revenue growth: peer costs and capex, year over year and quarter over quarter| Company | Period | Costs Y/Y | Capex Y/Y |
|---|---|---|---|
| Nucana Plc | Q4 2025 | - | - |
| Incyte Corporation | Q3 2026 | +9.8 % | -60.7 % |
| Tg Therapeutics Inc | Q2 2026 | +117.5 % | +597.6 % |
| Protagonist Therapeutics inc | Q2 2026 | - | -79.3 % |
| Iovance Biotherapeutics inc | Q3 2026 | +24.8 % | -55.4 % |
| Xencor Inc | Q2 2026 | - | +40.5 % |
Nucana Plc's Returns and Turnover vs Peers
ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover| Company | ROA | ROI | ROE |
|---|---|---|---|
| Nucana Plc | - | - | - |
| Incyte Corporation | 5.48% | 6.81% | 7.08% |
| Tg Therapeutics Inc | 33.59% | 39.26% | 72.30% |
| Protagonist Therapeutics inc | 11.02% | 11.66% | 11.80% |
| Iovance Biotherapeutics inc | - | - | - |
| Xencor Inc | - | - | - |
ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).
Nucana Plc's Valuation vs Peers
P/E, price to sales, PEG, price to cash flow and price to book| Company | P/E | Price / Sales |
|---|---|---|
| Nucana Plc | - | - |
| Incyte Corporation | 63.34 | 4.09 |
| Tg Therapeutics Inc | 23.51 | 12.69 |
| Protagonist Therapeutics inc | 128.38 | 32.97 |
| Iovance Biotherapeutics inc | - | 9.34 |
| Xencor Inc | - | 26.80 |
| PEERS AVERAGE | - | 7.26 |
P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.