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Evelo Biosciences Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Evelo Biosciences Inc (EVLO) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q3 2023
Competitors Tracked
141
Publicly traded peers
Peer Group Market Share
-
Share of combined sales, Q3 2023
Revenue Growth Y/Y
-
Peers: -11.39 %
Net Margin
-
Peers: -0.32 %
API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/EVLO/competitors
https://api.csimarket.com/api/v1/companies/EVLO/relationships
https://api.csimarket.com/api/v1/companies/EVLO/similar
Programmatic access for models, analytics, and integration workflows.

Evelo Biosciences Inc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Evelo Biosciences Inc - - - Yes
Competitors combined (135) 39% 68% 57% 39%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

EVLO Stock Performance relative to its Competitors

EVLO Competitors (weighted) Percent change over the selected range

Evelo Biosciences Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
45.5%beat U.S.A. 500
Competitors Combined
(50 of 110)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Evelo Biosciences Inc - -
Competitors combined (110) 40.4% 63.2%
High-Confidence Competitors (0) 40.4% 63.2%
Similar-Size Competitors (0) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Evelo Biosciences Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Ventyx Biosciences Inc 282.9% Outperformed
2 Moderna Inc 282.9% Outperformed
3 Damora Therapeutics Inc 282.9% Outperformed
4 Praxis Precision Medicines Inc 282.9% Outperformed
5 An2 Therapeutics Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Evelo Biosciences Inc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Publicly Traded Peers of Evelo Biosciences Inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Evelo Biosciences Inc 0.00 - -82.35 30
Beone Medicines Ltd 550,872.13 6,128.24 655.71 12,000
Abbvie Inc 463,275.89 64,386.00 6,316.00 57,000
Amgen Inc 229,301.44 38,095.00 8,743.00 13,000
Pfizer Inc 162,592.47 63,696.00 4,370.00 75,000
Vertex Pharmaceuticals Inc 133,421.11 12,587.20 4,405.20 405
SUBTOTAL 2,296,416.98 347,153.92 28,186.00 337,879
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Sources: Evelo Biosciences Inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Evelo Biosciences Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Evelo Biosciences Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Amgen Inc Reportable 100.00 % - -
Pfizer Inc U.S. Commercial Division 52.92 % International Commercial Division 36.88 % Global Hospital and Biosimilars Division 7.72 %
Vertex Pharmaceuticals Inc Pharmaceuticals 100.00 % - -
Teva Pharmaceutical Industries Limited United States Segment 41.09 % Europe Segment 30.49 % Other activities 15.14 %
Biogen Inc Reportable 100.00 % - -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Evelo Biosciences Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Evelo Biosciences Inc 0 - -2,744,967
Beone Medicines Ltd 550,872 510,686 54,642
Abbvie Inc 463,276 1,129,579 110,807
Amgen Inc 229,301 2,930,385 672,538
Pfizer Inc 162,592 849,280 58,267
Vertex Pharmaceuticals Inc 133,421 31,079,506 10,877,037
PEERS TOTAL 2,296,417 1,027,542 83,672
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Evelo Biosciences Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Beone Medicines Ltd United States 51.69 % China 31.19 % Europe 12.82 %
Pfizer Inc United States 58.91 % International Developed Markets 24.90 % International Emerging Markets 16.19 %
Vertex Pharmaceuticals Inc United States 61.68 % Europe 29.33 % Other Countries Outside of the United States and Europe 8.99 %
Bristol myers Squibb Company United States 67.79 % Non-US 29.98 % Other Region 2.24 %
Teva Pharmaceutical Industries Limited Europe 30.49 % - -

Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

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Evelo Biosciences Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 498 companies in Evelo Biosciences Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Evelo Biosciences Inc ranks #0 of 498 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 827, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Eli Lilly And Company 1,060,478 19.39 %
2 Johnson and Johnson 652,141 11.92 %
3 Beone Medicines Ltd 560,341 10.24 %
4 Abbvie Inc 468,722 8.57 %
5 Merck and Co Inc 1,234 5.2%
6 Novartis Ag 1,234 5.2%
7 Abbott Laboratories 1,234 5.2%
8 Novo Nordisk A 1,234 5.2%
9 Pfizer Inc 1,234 5.2%
10 Vertex Pharmaceuticals Inc 1,234 5.2%
0 Evelo Biosciences Inc 0 0.00 %
Full Industry Market Structure

Market cap and industry share for the rest of Evelo Biosciences Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-29.

Evelo Biosciences Inc's Valuation vs Competitive Position

Valuation multiples vs the Major Pharmaceutical Preparations industry average (341 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 25.5x -
EV / EBITDA - 17.3x -
P/B -3.6x 4.5x -8.2x
Return on Equity 313.08 % industry aggregate 301.62 %
Return on Invested Capital 282.72 % -2.97 % (avg) 285.69 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Evelo Biosciences Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 201920202021
Revenue Growth ---
Operating Margin ---
Return on Invested Capital -43.76 %-70.34 %-71.65 %
P/E ---

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Evelo Biosciences Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 827 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Evelo Biosciences Inc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Evelo Biosciences Inc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Evelo Biosciences Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

  • Return on equity 301.6 points above the industry aggregate.

Weaknesses

  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

  • A meaningful share of tracked competitors (39.20 %) show financial-distress signals, a possible opening to gain share.

Threats

  • Tracked peer group's revenue run-rate is broadly decelerating (-16.9% annualized).

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Evelo Biosciences Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Evelo Biosciences Inc 0.61 0.68 - -
Beone Medicines Ltd 2.30 3.16 0.23 0.73
Abbvie Inc 0.16 0.75 - 0.48
Amgen Inc 0.46 1.26 5.86 0.41
Pfizer Inc 0.04 1.24 0.71 0.31
Vertex Pharmaceuticals Inc 1.34 2.85 - 0.48
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Evelo Biosciences Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Evelo Biosciences Inc Q3 2023----
Beone Medicines Ltd Q2 2026+29.7 %+12.7 %+151.3 %+4.2 %
Abbvie Inc Q2 2026+10.2 %+13.3 %+284.3 %+418.8 %
Amgen Inc Q2 2026+9.5 %+16.7 %+65.9 %+30.6 %
Pfizer IncQ2 2026+2.6 %+4.0 %--
Vertex Pharmaceuticals IncQ2 2026+12.5 %+11.6 %+6.5 %+6.6 %
PEERS TOTAL+10.5 %+11.5 %+90.1 %+48.8 %
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Evelo Biosciences Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Evelo Biosciences Inc Q3 2023--+422.2 %-
Beone Medicines Ltd Q2 2026+6.4 %+4.5 %-57.0 %-32.6 %
Abbvie Inc Q2 2026-1.3 %+1.7 %+19.7 %+21.5 %
Amgen Inc Q2 2026-6.6 %+2.4 %+39.0 %-27.9 %
Pfizer IncQ2 2026+8.3 %+15.3 %-13.8 %+22.2 %
Vertex Pharmaceuticals IncQ2 2026+20.0 %+24.5 %-23.0 %-15.9 %
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Evelo Biosciences Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Evelo Biosciences Inc -----
Beone Medicines Ltd 7.82%10.32%14.24%6.581.07
Abbvie Inc 4.68%9.11%-4.993.66
Amgen Inc 9.48%13.08%89.32%4.071.86
Pfizer Inc2.12%2.53%4.91%4.981.60
Vertex Pharmaceuticals Inc16.88%19.97%23.31%6.191.03
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Evelo Biosciences Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Evelo Biosciences Inc -----
Beone Medicines Ltd 831.6889.89-220.83106.47
Abbvie Inc 73.907.201.484,541.92-
Amgen Inc 26.186.020.5638.4719.62
Pfizer Inc37.412.55--1.90
Vertex Pharmaceuticals Inc30.4810.60-113.836.59
PEERS AVERAGE81.476.61170.748.02
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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