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Crescent Biopharma Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Crescent Biopharma Inc (CBIO) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q2 2026
Competitors Tracked
19
Publicly traded peers
Peer Group Market Share
0.48 %
Share of combined sales, Q2 2026
Revenue Growth Y/Y
-
Peers: 108.67 %
Net Margin
-1,281.86 %
Peers: -75.49 %

Key Findings: Crescent Biopharma Inc vs Its Competitors

  • Profitability: Its -1,281.9% net margin compares with -75.5% for the peer group.
  • Scale: Crescent Biopharma Inc ranks #340 of 544 companies by market capitalization in the Major Pharmaceutical Preparations industry, holding 0.0% of industry market cap.
  • Peer revenue share: Crescent Biopharma Inc accounted for 0.5% of combined revenue among its tracked peer group.

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

CBIO Sales vs. its Competitors, Q2 2026

With a net margin of -1,281.86 %, Crescent Biopharma Inc reported lower profitability than its competitors (-75.49 %).

Crescent Biopharma Inc generated 0.48 % of the combined sales of its peer group.

API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/CBIO/competitors
https://api.csimarket.com/api/v1/companies/CBIO/relationships
https://api.csimarket.com/api/v1/companies/CBIO/similar
Programmatic access for models, analytics, and integration workflows.

Crescent Biopharma Inc vs. its Competitors, Q2 2026

Net margin

Crescent Biopharma Inc -1,281.9 %
Competitors combined -75.5 %

TTM = trailing twelve months. Run-rate annualizes the latest quarter (×4) and compares it to TTM. In millions of $. High-Confidence Competitors are named as a competitor directly in an SEC filing; Similar-Size Competitors are the closest peers by market-cap rank within the same industry; Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC, all independent of the competitor list.

Competitor Financial Benchmarking - TTM Commercial

TTM revenue, latest-quarter run-rate and net income/margin benchmarked across Crescent Biopharma Inc and its 4 competitor groupings. Available under Commercial License.

Entity TTM Revenue Latest Q ×4 Rev Run-rate vs TTM TTM Net Income TTM Net Margin
Crescent Biopharma Inc $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitors combined $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
High-Confidence Competitors (1) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Similar-Size Competitors (8) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitor Financial Benchmarking

TTM revenue, run-rate and net margin benchmarking across Crescent Biopharma Inc's competitor groups requires a Commercial License.

Crescent Biopharma Inc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Crescent Biopharma Inc - - - Yes
Competitors combined (19) 10% 60% 60% 24%
High-Confidence Competitors (1) 0% 100% 0% 0%
Similar-Size Competitors (10) 0% 50% 50% 56%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

Market Share of the Peer Group, Q2 2026

0.5%market share
  • Crescent Biopharma Inc0.5%
  • Competitors combined99.5%

Share of combined quarterly revenue of Crescent Biopharma Inc and its 19 tracked competitors.

See Crescent Biopharma Inc's full market share breakdown »

CBIO Stock Performance relative to its Competitors

CBIO Competitors (weighted) Percent change over the selected range

Crescent Biopharma Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
56.3%beat U.S.A. 500
Competitors Combined
(9 of 16)
0%beat U.S.A. 500
High-Confidence
(0 of 1)
10%beat U.S.A. 500
Similar-Size
(1 of 10)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Crescent Biopharma Inc 19.90 % Outperformed
Competitors combined (16) 40.4% 63.2%
High-Confidence Competitors (1) 40.4% 63.2%
Similar-Size Competitors (10) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Crescent Biopharma Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

CBIO Stock Performance relative to High-Confidence Competitors

CBIO High-Confidence Competitors (equal-weighted, 1) Percent change over the selected range

CBIO Stock Performance relative to Similar-Size Competitors

CBIO Similar-Size Competitors (equal-weighted, 10) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Iovance Biotherapeutics inc 282.9% Outperformed
2 Verona Pharma Plc 282.9% Outperformed
3 Shattuck Labs Inc 282.9% Outperformed
4 Day One Biopharmaceuticals Inc 282.9% Outperformed
5 Urogen Pharma Ltd 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Crescent Biopharma Inc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Crescent Biopharma Inc's Comment on Competition and Industry Peers

The company integrates the functional properties of ivonescimab with a proprietary molecule in its product development. Its candidate, CR-001, may benefit from clinical results associated with ivonescimab, potentially accelerating development timelines and reducing patient enrollment in late-stage trials. The biotechnology and biopharmaceutical industries involve continuous technological advancement and competition from major pharmaceutical and biotechnology companies, academic institutions, governmental agencies, and public and private research organizations. Competitors often possess greater financial resources and expertise in research and development, manufacturing, clinical trials, regulatory approvals, and marketing. Industry mergers and acquisitions may further enhance competitor resources.

Publicly Traded Peers of Crescent Biopharma Inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Crescent Biopharma Inc - - -8.88 44
Hutchmed china Limited 12,395.05 548.51 457.73 780
Verona Pharma Plc 9,718.43 221.67 -81.19 79
Blueprint Medicines Corporation 8,615.12 562.12 -155.73 582
Iovance Biotherapeutics inc 6,399.44 324.97 -289.52 975
Day One Biopharmaceuticals Inc 2,222.02 158.18 -193.37 178
SUBTOTAL 48,601.27 2,622.71 -1,319.70 4,481
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Sources: Crescent Biopharma Inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Crescent Biopharma Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Crescent Biopharma Inc's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Instil Bio Inc Named by the company 85% 2022 to 2026 3
X4 Pharmaceuticals Inc Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for Crescent Biopharma Inc's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

Crescent Biopharma Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Crescent Biopharma Inc Reportable 100.00 % - -
Hutchmed china Limited Other Ventures segment 47.94 % Marketed Products Subsegment 39.08 % Research and Development Subsegment 12.98 %
Blueprint Medicines Corporation Single Reportable Segment 100.00 % - -
Iovance Biotherapeutics inc Single reportable segment 100.00 % - -
Syndax Pharmaceuticals Inc Biopharmaceutical Cancer Therapeutics 100.00 % - -
Phathom Pharmaceuticals Inc Reportable Segment Aggregation Before Other Operating Segment 100.00 % - -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Crescent Biopharma Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Crescent Biopharma Inc - - -201,819
Hutchmed china Limited 12,395 703,221 586,836
Verona Pharma Plc 9,718 2,805,987 -1,027,684
Blueprint Medicines Corporation 8,615 965,844 -267,576
Iovance Biotherapeutics inc 6,399 333,302 -296,941
Day One Biopharmaceuticals Inc 2,222 888,663 -1,086,326
PEERS TOTAL 48,601 591,101 -295,429
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Crescent Biopharma Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Hutchmed china Limited CN 74.28 % United States and Others 25.72 % -
Iovance Biotherapeutics inc US 98.66 % Non Us 1.34 % -

Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

Crescent Biopharma Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 498 companies in Crescent Biopharma Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Crescent Biopharma Inc ranks #340 of 498 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 824, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Eli Lilly And Company 1,026,343 19.37 %
2 Johnson and Johnson 628,899 11.87 %
3 Beone Medicines Ltd 532,304 10.04 %
4 Abbvie Inc 461,328 8.70 %
5 Merck and Co Inc 1,234 5.2%
6 Novartis Ag 1,234 5.2%
7 Abbott Laboratories 1,234 5.2%
8 Novo Nordisk A 1,234 5.2%
9 Pfizer Inc 1,234 5.2%
10 Vertex Pharmaceuticals Inc 1,234 5.2%
340 Crescent Biopharma Inc 41 0.00 %
Full Industry Market Structure

Market cap and industry share for the rest of Crescent Biopharma Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-10-02.

Crescent Biopharma Inc's Same-Size Peers & Stock Performance

Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.
Rank Company Market Cap TTM Return 3M Momentum Beta Sharpe (1Y)
335 Filana Therapeutics Inc 47 -69.68 % -18.47 % 1.16 -0.95
336 Celularity Inc 44 -28.92 % 93.85 % 1.68 0.32
337 Werewolf Therapeutics Inc 44 -53.75 % 137.97 % 1.84 -0.02
338 Gossamer Bio Inc 44 326.31 % 5,965.71 % 0.12 -61.08
339 Annovis Bio Inc 1,234 12.3% 4.5% 1.10 0.80
340 Crescent Biopharma Inc 41 19.92 % -14.86 % 1.22 0.55
341 Pds Biotechnology Corp 1,234 12.3% 4.5% 1.10 0.80
342 Aprea Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
343 Incannex Healthcare Inc 1,234 12.3% 4.5% 1.10 0.80
344 Elicio Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
345 Actinium Pharmaceuticals Inc 1,234 12.3% 4.5% 1.10 0.80
Full Same-Size Peer Performance

Market cap, return, momentum, beta and Sharpe ratio for the rest of Crescent Biopharma Inc's same-size peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-10-02. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.

Crescent Biopharma Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 20182019202020212022202320242025
Revenue Growth --------
Operating Margin ----5,470.69 %----
Return on Invested Capital -11.56 %-17.57 %-18.20 %-30.30 %-44.02 %-38.82 %-151.98 %-65.75 %
P/E --------

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Crescent Biopharma Inc's BCG Growth-Share Matrix

Relative market share (vs Crescent Biopharma Inc's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.

Question Mark Star Dog Cash Cow Relative Market Share (vs largest competitor) Industry Revenue Growth (%) Crescent Biopharma Inc

Crescent Biopharma Inc falls in the Dog quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 8.1% (median, trailing 12 months).

Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.

Crescent Biopharma Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 824 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Crescent Biopharma Inc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Crescent Biopharma Inc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Crescent Biopharma Inc's Industry Attractiveness & Competitive Strength

A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.

High Strength
Medium Strength
Low Strength
High Attractiveness
Invest / Grow
Invest / Grow
Selective
Medium Attractiveness
Invest / Grow
Selective
Harvest
Low Attractiveness
Selective
Harvest
Harvest / Divest Crescent Biopharma Inc

Crescent Biopharma Inc falls in the Low attractiveness / Low strength cell: Harvest / Divest.

Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.

Crescent Biopharma Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

  • Outperforming the U.S.A. 500 over the trailing 12 months.

Weaknesses

  • Return on equity 22.6 points below the industry aggregate.
  • Low relative market share vs the industry leader (0.00x).
  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

No rule matched.

Threats

No rule matched.

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Crescent Biopharma Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Crescent Biopharma Inc 7.94 8.37 - -
Hutchmed china Limited 0.23 4.96 0.10 0.31
Verona Pharma Plc 8.83 10.47 0.86 0.45
Blueprint Medicines Corporation 0.36 3.16 2.48 0.47
Iovance Biotherapeutics inc 1.26 3.60 0.00 0.36
Day One Biopharmaceuticals Inc 1.43 9.15 - 0.30
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Crescent Biopharma Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Crescent Biopharma Inc Q2 2026-+70.4 %--
Hutchmed china LimitedQ4 2025-13.0 %-13.0 %+1,099.2 %+1,099.2 %
Verona Pharma PlcQ2 2025-+35.3 %--
Blueprint Medicines CorporationQ1 2025+55.5 %+2.1 %-99.4 %-
Iovance Biotherapeutics inc Q2 2026+65.7 %+39.0 %--
Day One Biopharmaceuticals Inc Q4 2025+83.9 %+35.0 %--
PEERS TOTAL+31.1 %+5.1 %--
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Crescent Biopharma Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Crescent Biopharma Inc Q2 2026---90.7 %-99.8 %
Hutchmed china LimitedQ4 2025-3.6 %-3.6 %-44.2 %-44.2 %
Verona Pharma PlcQ2 2025----
Blueprint Medicines CorporationQ1 2025-12.2 %-62.4 %+65.9 %+96.5 %
Iovance Biotherapeutics inc Q2 2026-10.8 %+2.6 %-27.1 %-17.7 %
Day One Biopharmaceuticals Inc Q4 2025----
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Crescent Biopharma Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Crescent Biopharma Inc -----
Hutchmed china Limited26.11%30.87%36.98%4.3318.01
Verona Pharma Plc---4.83-
Blueprint Medicines Corporation---7.381.47
Iovance Biotherapeutics inc ---3.902.81
Day One Biopharmaceuticals Inc ---7.80-
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Crescent Biopharma Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Crescent Biopharma Inc -----
Hutchmed china Limited27.3122.600.02-10.01
Verona Pharma Plc-43.84-290.8234.92
Blueprint Medicines Corporation-15.33-841.7325.18
Iovance Biotherapeutics inc -19.69--8.69
Day One Biopharmaceuticals Inc -14.05-30.815.04
PEERS AVERAGE-18.5377.6610.18
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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