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Anavex Life Sciences's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Anavex Life Sciences (AVXL) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q3 2026
Competitors Tracked
23
Publicly traded peers
Peer Group Market Share
-
Share of combined sales, Q3 2026
Revenue Growth Y/Y
-
Peers: 11.24 %
Net Margin
-
Peers: 17.83 %

Key Findings: Anavex Life Sciences vs Its Competitors

  • TTM: Trailing 12-month revenue of 4M vs 42,816M combined for tracked competitors (0.0% combined share).
  • Scale: Anavex Life Sciences ranks #86 of 165 companies by market capitalization in the Biotechnology & Pharmaceuticals industry, holding 0.0% of industry market cap.
  • Peer differentiation: Revenue per employee of $0.13M compares with $2.08M for the peer group (0.1x).

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/AVXL/competitors
https://api.csimarket.com/api/v1/companies/AVXL/relationships
https://api.csimarket.com/api/v1/companies/AVXL/similar
Programmatic access for models, analytics, and integration workflows.

Anavex Life Sciences vs. its Competitors, Q3 2026

TTM net margin

Anavex Life Sciences -298.7 %
Competitors combined +19.0 %

TTM = trailing twelve months. Run-rate annualizes the latest quarter (×4) and compares it to TTM. In millions of $. High-Confidence Competitors are named as a competitor directly in an SEC filing; Similar-Size Competitors are the closest peers by market-cap rank within the same industry; Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC, all independent of the competitor list.

Competitor Financial Benchmarking - TTM Commercial

TTM revenue, latest-quarter run-rate and net income/margin benchmarked across Anavex Life Sciences and its 4 competitor groupings. Available under Commercial License.

Entity TTM Revenue Latest Q ×4 Rev Run-rate vs TTM TTM Net Income TTM Net Margin
Anavex Life Sciences Corp $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitors combined $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
High-Confidence Competitors (6) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Similar-Size Competitors (7) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitor Financial Benchmarking

TTM revenue, run-rate and net margin benchmarking across Anavex Life Sciences's competitor groups requires a Commercial License.

Anavex Life Sciences's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Anavex Life Sciences Corp - - - No
Competitors combined (23) 57% 63% 38% 40%
High-Confidence Competitors (9) 100% 88% 25% 22%
Similar-Size Competitors (10) 40% 60% 60% 33%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

AVXL Stock Performance relative to its Competitors

AVXL Competitors (weighted) Percent change over the selected range

Anavex Life Sciences's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
38.1%beat U.S.A. 500
Competitors Combined
(8 of 21)
100%beat U.S.A. 500
High-Confidence
(9 of 9)
40%beat U.S.A. 500
Similar-Size
(4 of 10)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Anavex Life Sciences Corp -72.70 % Underperformed
Competitors combined (21) 40.4% 63.2%
High-Confidence Competitors (9) 40.4% 63.2%
Similar-Size Competitors (10) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Anavex Life Sciences's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

AVXL Stock Performance relative to High-Confidence Competitors

AVXL High-Confidence Competitors (equal-weighted, 10) Percent change over the selected range

AVXL Stock Performance relative to Similar-Size Competitors

AVXL Similar-Size Competitors (equal-weighted, 10) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Spruce Biosciences Inc 282.9% Outperformed
2 Praxis Precision Medicines Inc 282.9% Outperformed
3 Vigil Neuroscience Inc 282.9% Outperformed
4 Biogen Inc 282.9% Outperformed
5 Acumen Pharmaceuticals Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Anavex Life Sciences's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Anavex Life Sciences's Comment on Competition and Industry Peers

The company operates in the drug discovery and development sector, focusing on treatments for pancreatic cancer, Alzheimer's disease, and other central nervous system disorders. Its competitors include biomedical development companies, academic institutions, and government agencies both in the United States and internationally. These competitors may possess greater financial resources, established market presence, and expertise in research, development, manufacturing, clinical testing, and regulatory approvals. Competition also occurs in recruiting scientific personnel, establishing clinical trial sites, patient registration, and technology acquisition or development. The company’s approach involves activation of SIGMAR1 and the use of SIGMAR1 agonists such as ANAVEX® 2-73 as a disease-modifying treatment.

Publicly Traded Peers of Anavex Life Sciences Corp

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Anavex Life Sciences Corp 219.24 4.36 -13.02 34
Amgen Inc 230,460.16 38,095.00 8,743.00 13,000
Biogen Inc 33,697.19 9,937.40 1,371.90 7,500
Neurocrine Biosciences Inc 14,416.07 3,373.90 705.50 2,000
Praxis Precision Medicines Inc 8,185.92 8.55 -339.13 168
Denali Therapeutics Inc 3,898.01 110.69 0.99 503
SUBTOTAL 298,751.55 52,831.99 8,987.64 25,460
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Sources: Anavex Life Sciences Corp's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Anavex Life Sciences Corp versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Anavex Life Sciences's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Acumen Pharmaceuticals Inc Named by the company 85% 2022 to 2026 3
Johnson & Johnson Named by the company 85% 2022 to 2026 3
Eli Lilly & Co. Named by the company 85% 2022 to 2026 3
Pfizer Inc. Named by the company 85% 2022 to 2026 3
Abbvie Plc Named by the company 85% 2022 to 2026 3
Merck & Co. Inc. Named by the company 85% 2022 to 2026 3
GlaxoSmithKline Plc Named by the company 85% 2022 to 2026 3
Roche Holding AG Named by the company 85% 2022 to 2026 3
Biogen Named by the company 85% 2022 to 2026 3
Novartis AG Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for Anavex Life Sciences's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

Anavex Life Sciences's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Amgen Inc Reportable 100.00 % - -
Biogen Inc Reportable 100.00 % - -
Neurocrine Biosciences Inc Reportable 100.00 % - -
Acadia Pharmaceuticals Inc Reportable Segment Aggregation Before Other Operating Segment 100.00 % - -
Recursion Pharmaceuticals Inc Reportable 100.00 % - -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Anavex Life Sciences's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Anavex Life Sciences Corp 219 128,239 -383,000
Amgen Inc 230,460 2,930,385 672,538
Biogen Inc 33,697 1,324,987 182,920
Neurocrine Biosciences Inc 14,416 1,686,950 352,750
Praxis Precision Medicines Inc 8,186 50,911 -2,018,607
Denali Therapeutics Inc 3,898 220,068 1,962
PEERS TOTAL 298,532 2,077,701 353,994
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Anavex Life Sciences's Position in Industry Market Structure

Market-capitalization share and concentration across all 159 companies in Anavex Life Sciences's industry classification, broader than the peer set above. Market cap in millions of $.

Anavex Life Sciences ranks #86 of 159 companies by market capitalization in its industry, holding 0.02 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 1,324, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Amgen Inc 230,460 25.95 %
2 Gilead Sciences Inc 188,041 21.17 %
3 Moderna Inc 80,977 9.12 %
4 Argenx Se 64,092 7.22 %
5 Revolution Medicines Inc 1,234 5.2%
6 Biogen Inc 1,234 5.2%
7 Biontech Se 1,234 5.2%
8 Exelixis Inc 1,234 5.2%
9 Neurocrine Biosciences Inc 1,234 5.2%
10 Halozyme Therapeutics Inc 1,234 5.2%
86 Anavex Life Sciences Corp 219 0.02 %
Full Industry Market Structure

Market cap and industry share for the rest of Anavex Life Sciences's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-29.

Anavex Life Sciences's Same-Size Peers & Stock Performance

Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.
Rank Company Market Cap TTM Return 3M Momentum Beta Sharpe (1Y)
81 Evaxion A 229 -19.83 % -4.17 % 0.76 0.26
82 Armata Pharmaceuticals Inc 223 24.25 % -31.25 % 0.45 0.72
83 Protalix Biotherapeutics inc 222 30.58 % 16.96 % 0.85 0.67
84 Compugen Ltd 220 68.12 % -1.69 % 1.59 1.04
85 Scinai Immunotherapeutics Ltd 1,234 12.3% 4.5% 1.10 0.80
86 Anavex Life Sciences Corp 219 -72.74 % -11.24 % 1.58 -1.09
87 Alector Inc 1,234 12.3% 4.5% 1.10 0.80
88 Compass Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
89 Protara Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
90 Quince Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
91 Coherus Oncology inc 1,234 12.3% 4.5% 1.10 0.80
Full Same-Size Peer Performance

Market cap, return, momentum, beta and Sharpe ratio for the rest of Anavex Life Sciences's same-size peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-09-29. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.

Anavex Life Sciences's Valuation vs Competitive Position

Valuation multiples vs the Biotechnology & Pharmaceuticals industry average (93 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Biotechnology & Pharmaceuticals industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 26.7x -
EV / EBITDA - 21.3x -
P/B 2.4x 5.1x -2.7x
Return on Equity -12.29 % industry aggregate -8.86 %
Return on Invested Capital -8.15 % -6.17 % (avg) -1.98 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Anavex Life Sciences's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 20182019202020212022202320242025
Revenue Growth 87.33 %6.29 %24.89 %500.00 %-13.78 %-39.35 %--
Operating Margin -4,482.44 %-5,200.23 %-4,490.98 %-852.77 %-992.84 %-2,005.31 %--
Return on Invested Capital -49.31 %-65.26 %-44.67 %-20.03 %-14.24 %-17.38 %-20.77 %-23.35 %
P/E --------

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Anavex Life Sciences's BCG Growth-Share Matrix

Relative market share (vs Anavex Life Sciences's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.

Question Mark Star Dog Cash Cow Relative Market Share (vs largest competitor) Industry Revenue Growth (%) Anavex Life Sciences

Anavex Life Sciences falls in the Question Mark quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 10.0% (median, trailing 12 months).

Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.

Anavex Life Sciences's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 1,324 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Anavex Life Sciences's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Anavex Life Sciences's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Anavex Life Sciences's Industry Attractiveness & Competitive Strength

A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.

High Strength
Medium Strength
Low Strength
High Attractiveness
Invest / Grow
Invest / Grow
Selective
Medium Attractiveness
Invest / Grow
Selective
Harvest
Low Attractiveness
Selective
Harvest
Harvest / Divest Anavex Life Sciences

Anavex Life Sciences falls in the Low attractiveness / Low strength cell: Harvest / Divest.

Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.

Anavex Life Sciences's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

No rule matched.

Weaknesses

  • Return on equity 8.9 points below the industry aggregate.
  • Underperforming the U.S.A. 500 over the trailing 12 months.
  • Low relative market share vs the industry leader (0.00x).

Opportunities

  • Industry revenue growing at a healthy 10.0% median pace.
  • A meaningful share of tracked competitors (40.00 %) show financial-distress signals, a possible opening to gain share.

Threats

No rule matched.

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Anavex Life Sciences's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Anavex Life Sciences Corp 16.47 16.74 - 0.04
Amgen Inc 0.46 1.26 5.86 0.41
Biogen Inc - 2.74 0.35 0.34
Neurocrine Biosciences Inc 0.54 2.84 - 0.70
Praxis Precision Medicines Inc 11.53 11.58 - 0.01
Denali Therapeutics Inc 2.28 9.16 - 0.10
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Anavex Life Sciences's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Anavex Life Sciences Corp Q2 2026----
Amgen Inc Q2 2026+9.5 %+16.7 %+65.9 %+30.6 %
Biogen Inc Q1 2026+1.9 %+8.7 %+32.8 %-
Neurocrine Biosciences Inc Q2 2026+39.5 %+17.7 %+34.3 %-27.0 %
Praxis Precision Medicines Inc Q2 2026----
Denali Therapeutics Inc Q2 2026----
PEERS TOTAL+9.6 %+15.0 %+102.5 %+68.6 %
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Anavex Life Sciences's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Anavex Life Sciences Corp Q2 2026----
Amgen Inc Q2 2026-6.6 %+2.4 %+39.0 %-27.9 %
Biogen Inc Q1 2026+5.0 %+33.4 %+8.7 %-15.0 %
Neurocrine Biosciences Inc Q2 2026+125.2 %+68.1 %-37.6 %-14.3 %
Praxis Precision Medicines Inc Q2 2026--+1,717.9 %+1,541.9 %
Denali Therapeutics Inc Q2 2026--+592.0 %+1,100.5 %
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Anavex Life Sciences's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Anavex Life Sciences Corp -----
Amgen Inc 9.48%13.08%89.32%4.071.86
Biogen Inc 4.71%5.23%7.54%6.961.13
Neurocrine Biosciences Inc 14.73%17.51%21.13%4.400.89
Praxis Precision Medicines Inc -----
Denali Therapeutics Inc 0.09%0.09%0.11%56.38-
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Anavex Life Sciences's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Anavex Life Sciences Corp -50.28-12.771.95
Amgen Inc 26.316.050.5638.6619.72
Biogen Inc 24.363.39-45.861.81
Neurocrine Biosciences Inc 20.224.270.15215.493.90
Praxis Precision Medicines Inc -957.08-25.836.10
Denali Therapeutics Inc -35.21-64.624.67
PEERS AVERAGE33.245.6540.997.55
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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