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Akari Therapeutics Plc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Akari Therapeutics Plc (AKTX) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q1 2026
Competitors Tracked
36
Publicly traded peers
Peer Group Market Share
-
Share of combined sales, Q1 2026
Revenue Growth Y/Y
-
Peers: 8.16 %
Net Margin
-
Peers: 12.97 %
API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/AKTX/competitors
https://api.csimarket.com/api/v1/companies/AKTX/relationships
https://api.csimarket.com/api/v1/companies/AKTX/similar
Programmatic access for models, analytics, and integration workflows.

Akari Therapeutics Plc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Akari Therapeutics Plc - - - No
Competitors combined (35) 45% 74% 63% 30%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

AKTX Stock Performance relative to its Competitors

AKTX Competitors (weighted) Percent change over the selected range

Akari Therapeutics Plc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
45.5%beat U.S.A. 500
Competitors Combined
(15 of 33)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Akari Therapeutics Plc -74.40 % Underperformed
Competitors combined (33) 40.4% 63.2%
High-Confidence Competitors (0) 40.4% 63.2%
Similar-Size Competitors (0) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Akari Therapeutics Plc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Prelude Therapeutics Inc 282.9% Outperformed
2 Immunovant Inc 282.9% Outperformed
3 Teva Pharmaceutical Industries Limited 282.9% Outperformed
4 Puma Biotechnology Inc 282.9% Outperformed
5 Therapeuticsmd Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Akari Therapeutics Plc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Akari Therapeutics Plc's Comment on Competition and Industry Peers

The company operates in the biotechnology and pharmaceutical industries, focusing on the oncology subsector. This sector is characterized by rapid technological change, intense competition, and strong protection of intellectual property. The company competes with larger, better-funded biotechnology and pharmaceutical firms, academic institutions, governmental agencies, and both public and private research organizations. It also faces competition from smaller or early-stage companies, universities, and other research institutions developing cancer therapeutics. Its product candidates may compete with existing and emerging therapies, including surgery, radiation, chemotherapy, hormone therapy, biologic therapies such as monoclonal and bispecific antibodies, immunotherapy, cell-based therapy, and targeted therapy. Competition extends across the oncology market for cost-effective and reimbursable cancer treatments. Market acceptance and achieving significant market share may be challenging due to competition and preferences by insurers or reimbursement authorities for generic or specific branded products. Bayer Pharmaceuticals is identified as a competitor in the company's filings.

Publicly Traded Peers of Akari Therapeutics Plc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Akari Therapeutics Plc 1,180,444.71 - -28.05 6
Beone Medicines Ltd 543,751.77 6,128.24 655.71 12,000
Abbvie Inc 473,290.90 64,386.00 6,316.00 57,000
Amgen Inc 227,217.92 38,095.00 8,743.00 13,000
Bristol myers Squibb Company 130,437.12 49,186.00 9,274.00 32,500
Regeneron Pharmaceuticals Inc 79,007.10 15,534.70 4,328.70 15,410
SUBTOTAL 2,726,680.06 205,119.79 27,830.55 199,298
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Sources: Akari Therapeutics Plc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Akari Therapeutics Plc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Akari Therapeutics Plc's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
eculizumab Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for Akari Therapeutics Plc's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

Akari Therapeutics Plc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Amgen Inc Reportable 100.00 % - -
Teva Pharmaceutical Industries Limited United States Segment 41.09 % Europe Segment 30.49 % Other activities 15.14 %
Viatris Inc Developed Markets 57.61 % Greater China 19.34 % Emerging Markets 15.28 %
Mannkind Corporation All Other Segments 100.00 % - -
Journey Medical Corp Dermatological segment 100.00 % - -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Akari Therapeutics Plc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Akari Therapeutics Plc 1,180,445 - -4,674,667
Beone Medicines Ltd 543,752 510,686 54,642
Abbvie Inc 473,291 1,129,579 110,807
Amgen Inc 227,218 2,930,385 672,538
Bristol myers Squibb Company 130,437 1,513,415 285,354
Regeneron Pharmaceuticals Inc 79,007 1,008,092 280,902
PEERS TOTAL 1,546,235 1,029,242 139,788
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Akari Therapeutics Plc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Beone Medicines Ltd United States 51.69 % China 31.19 % Europe 12.82 %
Bristol myers Squibb Company United States 67.79 % Non-US 29.98 % Other Region 2.24 %
Teva Pharmaceutical Industries Limited Europe 30.49 % - -
Therapeuticsmd Inc Non Us 66.30 % US 33.70 % -

Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

Akari Therapeutics Plc's Position in Industry Market Structure

Market-capitalization share and concentration across all 498 companies in Akari Therapeutics Plc's industry classification, broader than the peer set above. Market cap in millions of $.

Akari Therapeutics Plc ranks #0 of 498 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 824, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Eli Lilly And Company 1,054,271 19.27 %
2 Johnson and Johnson 662,243 12.10 %
3 Beone Medicines Ltd 543,752 9.94 %
4 Abbvie Inc 473,291 8.65 %
5 Merck and Co Inc 1,234 5.2%
6 Novartis Ag 1,234 5.2%
7 Abbott Laboratories 1,234 5.2%
8 Novo Nordisk A 1,234 5.2%
9 Pfizer Inc 1,234 5.2%
10 Vertex Pharmaceuticals Inc 1,234 5.2%
0 Akari Therapeutics Plc - 0.00 %
Full Industry Market Structure

Market cap and industry share for the rest of Akari Therapeutics Plc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-29.

Akari Therapeutics Plc's Valuation vs Competitive Position

Valuation multiples vs the Major Pharmaceutical Preparations industry average (341 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 25.1x -
EV / EBITDA - 17.3x -
P/B 48,848.9x 4.5x +48,844.4x
Return on Equity -123.29 % industry aggregate -140.19 %
Return on Invested Capital -54.37 % -2.95 % (avg) -51.42 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Akari Therapeutics Plc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 201920202021202320242025
Revenue Growth ------
Operating Margin ------
Return on Invested Capital 478.52 %-95.80 %-91.72 %--251.12 %-29.48 %
P/E ------

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Akari Therapeutics Plc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 824 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Akari Therapeutics Plc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Akari Therapeutics Plc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Akari Therapeutics Plc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

No rule matched.

Weaknesses

  • Return on equity 140.2 points below the industry aggregate.
  • Underperforming the U.S.A. 500 over the trailing 12 months.

Opportunities

  • A meaningful share of tracked competitors (30.00 %) show financial-distress signals, a possible opening to gain share.

Threats

  • Tracked peer group's revenue run-rate is broadly decelerating (-5.8% annualized).

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Akari Therapeutics Plc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Akari Therapeutics Plc 0.23 0.26 0.04 -
Beone Medicines Ltd 2.30 3.16 0.23 0.73
Abbvie Inc 0.16 0.75 - 0.48
Amgen Inc 0.46 1.26 5.86 0.41
Bristol myers Squibb Company 0.49 1.35 2.31 0.54
Regeneron Pharmaceuticals Inc 0.57 3.74 0.06 0.38
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Akari Therapeutics Plc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Akari Therapeutics PlcQ1 2026----
Beone Medicines Ltd Q2 2026+29.7 %+12.7 %+151.3 %+4.2 %
Abbvie Inc Q2 2026+10.2 %+13.3 %+284.3 %+418.8 %
Amgen Inc Q2 2026+9.5 %+16.7 %+65.9 %+30.6 %
Bristol myers Squibb CompanyQ2 2026+5.7 %+12.9 %+152.6 %+23.8 %
Regeneron Pharmaceuticals Inc Q2 2026+16.7 %+19.0 %-6.8 %+78.3 %
PEERS TOTAL+10.2 %+14.2 %+98.5 %+56.3 %
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Akari Therapeutics Plc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Akari Therapeutics PlcQ1 2026----
Beone Medicines Ltd Q2 2026+6.4 %+4.5 %-57.0 %-32.6 %
Abbvie Inc Q2 2026-1.3 %+1.7 %+19.7 %+21.5 %
Amgen Inc Q2 2026-6.6 %+2.4 %+39.0 %-27.9 %
Bristol myers Squibb CompanyQ2 2026+10.5 %+8.9 %-15.5 %-12.1 %
Regeneron Pharmaceuticals Inc Q2 2026+109.2 %+54.4 %+9.7 %+4.2 %
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Akari Therapeutics Plc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Akari Therapeutics Plc-----
Beone Medicines Ltd 7.82%10.32%14.24%6.581.07
Abbvie Inc 4.68%9.11%-4.993.66
Amgen Inc 9.48%13.08%89.32%4.071.86
Bristol myers Squibb Company10.27%13.58%46.65%4.605.37
Regeneron Pharmaceuticals Inc 10.60%11.83%13.81%2.620.49
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Akari Therapeutics Plc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Akari Therapeutics Plc---6,346,476.9582,089.34
Beone Medicines Ltd 820.9388.73-217.97105.09
Abbvie Inc 75.497.351.514,640.11-
Amgen Inc 25.945.960.5538.1219.44
Bristol myers Squibb Company14.022.650.20-5.84
Regeneron Pharmaceuticals Inc 18.465.096.08175.422.49
PEERS AVERAGE97.9713.29465.0229.56
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.