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111 Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of 111 Inc (YI) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q4 2025
Competitors Tracked
3
Publicly traded peers
Peer Group Market Share
0.91 %
vs 1.18 % a year ago
Revenue Growth Y/Y
-9.00 %
Peers: 17.80 %
Net Margin
-0.18 %
Peers: 2.36 %

Key Findings: 111 Inc vs Its Competitors

  • TTM: Trailing 12-month revenue of 1,747M vs 189,880M combined for tracked competitors (0.9% combined share).
  • Trending: Latest-quarter revenue run-rate is accelerating (+311.1% annualized vs trailing 12 months), vs accelerating (+311.1%) for its tracked peer group.
  • Growth: 111 Inc generated -9.0% revenue growth year over year in Q4 2025, vs 17.8% for its tracked competitors combined.
  • Profitability: Its -0.2% net margin compares with 2.4% for the peer group.
  • Scale: 111 Inc ranks #7 of 16 companies by market capitalization in the Pharmacy Services & Retail Drugstore industry, holding 0.2% of industry market cap.
  • Peer revenue share: 111 Inc accounted for 0.9% of combined revenue among its tracked peer group, down from 1.2% a year earlier.
  • Peer differentiation: Revenue per employee of $0.54M compares with $0.28M for the peer group (1.9x).

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

YI Sales vs. its Competitors, Q4 2025

111 Inc reported revenue contraction of 9.00 % year on year in Q4 2025, below its competitors' combined revenue growth of 17.80 %.

With a net margin of -0.18 %, 111 Inc reported lower profitability than its competitors (2.36 %).

111 Inc generated 0.91 % of the combined sales of its peer group, down from 1.18 % a year earlier.

API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/YI/competitors
https://api.csimarket.com/api/v1/companies/YI/relationships
https://api.csimarket.com/api/v1/companies/YI/similar
Programmatic access for models, analytics, and integration workflows.

111 Inc vs. its Competitors, Q4 2025

Revenue growth, year on year

111 Inc -9.0 %
Competitors combined +17.8 %

Net margin

111 Inc -0.2 %
Competitors combined +2.4 %

Revenue run-rate vs trailing 12 months

111 Inc +311.1 %
Competitors combined +311.1 %

TTM net margin

111 Inc -0.2 %
Competitors combined +2.4 %

TTM = trailing twelve months. Run-rate annualizes the latest quarter (×4) and compares it to TTM. In millions of $. High-Confidence Competitors are named as a competitor directly in an SEC filing; Similar-Size Competitors are the closest peers by market-cap rank within the same industry; Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC, all independent of the competitor list.

Competitor Financial Benchmarking - TTM Commercial

TTM revenue, latest-quarter run-rate and net income/margin benchmarked across 111 Inc and its 4 competitor groupings. Available under Commercial License.

Entity TTM Revenue Latest Q ×4 Rev Run-rate vs TTM TTM Net Income TTM Net Margin
111 Inc $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitors combined $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
High-Confidence Competitors (1) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Similar-Size Competitors (10) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Similar Growth & Profitability (2) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitor Financial Benchmarking

TTM revenue, run-rate and net margin benchmarking across 111 Inc's competitor groups requires a Commercial License.

For context: the Pharmacy Services & Retail Drugstore industry grew revenue 6.7% year over year, combined, vs -9.0% for 111 Inc. 111 Inc's share of combined industry revenue moved from 0.49% to 0.42%, a loss of 0.07 percentage points.

111 Inc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
111 Inc No No No No
Competitors combined (3) 67% 100% 100% 0%
High-Confidence Competitors (1) 100% 100% 100% 0%
Similar-Size Competitors (10) 56% 60% 60% 0%
Similar Growth & Profitability (8) 37.50 % (3 of 8) 62.50 % (5 of 8) 62.50 % (5 of 8) 12.50 % (1 of 8)

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

Market Share of the Peer Group, Q4 2025

0.9%market share
  • 111 Inc0.9%
  • Competitors combined99.1%

Share of combined quarterly revenue of 111 Inc and its 3 tracked competitors.

See 111 Inc's full market share breakdown »

YI Stock Performance relative to its Competitors

YI Competitors (weighted) Percent change over the selected range

111 Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
0%beat U.S.A. 500
Competitors Combined
(0 of 3)
0%beat U.S.A. 500
High-Confidence
(0 of 1)
44.4%beat U.S.A. 500
Similar-Size
(4 of 9)
25%beat U.S.A. 500
Similar Growth & Profitability
(1 of 4)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
111 Inc -30.20 % Underperformed
Competitors combined (3) 40.4% 63.2%
High-Confidence Competitors (1) 40.4% 63.2%
Similar-Size Competitors (9) 40.4% 63.2%
Similar Growth & Profitability (4) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for 111 Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

YI Stock Performance relative to High-Confidence Competitors

YI High-Confidence Competitors (equal-weighted, 1) Percent change over the selected range

YI Stock Performance relative to Similar-Size Competitors

YI Similar-Size Competitors (equal-weighted, 10) Percent change over the selected range

YI Stock Performance relative to Similar Growth & Profitability Competitors

YI Similar Growth & Profitability Competitors (equal-weighted, 8) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Zto Express cayman Inc 282.9% Outperformed
2 Jd com Inc 282.9% Outperformed
3 Huya inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for 111 Inc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

111 Inc's Comment on Competition and Industry Peers

The company operates in the online healthcare industry and competes with other online healthcare platforms, offline pharmacy chains, and independent pharmacies. It utilizes a pricing intelligence system that employs data mining to monitor competitors' pricing, optimize its pricing strategy, and make automatic adjustments. The company generally offers pricing lower than offline competitors and encourages marketplace sellers to set comparable prices. Additionally, it provides data services to pharmaceutical companies using its pricing intelligence system. The company maintains a secure online platform with continuous monitoring.

Publicly Traded Peers of 111 Inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
111 Inc 567.33 1,747.03 -3.22 3,238
Jd com Inc 79,573.15 182,144.12 3,309.00 642,940
Zto Express cayman Inc 15,989.24 6,831.51 1,298.52 23,399
Huya inc 526.33 904.73 -16.10 2,800
SUBTOTAL 96,656.05 191,627.39 4,588.20 672,377

Sources: 111 Inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on 111 Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

111 Inc's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Ali Health Named by the company 85% 2022 to 2026 3
JD.com Named by the company 85% 2022 to 2026 3
Zto Express cayman Inc Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for 111 Inc's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

111 Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Jd com Inc Jd Logistics 42.90 % New Business 26.33 % -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

111 Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
111 Inc 567 539,539 -994
Jd com Inc 79,573 283,299 5,147
Zto Express cayman Inc 15,989 291,958 55,495
Huya inc 526 323,119 -5,750
PEERS TOTAL 96,089 283,768 6,862

111 Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 14 companies in 111 Inc's industry classification, broader than the peer set above. Market cap in millions of $.

111 Inc ranks #7 of 14 companies by market capitalization in its industry, holding 0.17 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 2,661, indicating a highly concentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Cvs Health Corporation 110,135 32.65 %
2 Mckesson Corporation 107,101 31.75 %
3 Cencora Inc 60,169 17.84 %
4 Cardinal Health Inc 55,136 16.35 %
5 Guardian Pharmacy Services Inc 1,234 5.2%
6 Herbalife Ltd 1,234 5.2%
7 111 Inc 567 0.17 %
8 Nu Skin Enterprises Inc 1,234 5.2%
9 Zerostack Corp 1,234 5.2%
10 Petmed Express Inc 1,234 5.2%
Full Industry Market Structure

Market cap and industry share for the rest of 111 Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-10-01.

111 Inc's Same-Size Peers & Stock Performance

Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.
Rank Company Market Cap TTM Return 3M Momentum Beta Sharpe (1Y)
2 Mckesson Corporation 107,101 16.30 % 9.75 % 0.02 0.51
3 Cencora Inc 60,169 -0.73 % 0.22 % -0.03 0.00
4 Cardinal Health Inc 55,136 48.84 % -1.49 % 0.24 1.40
5 Guardian Pharmacy Services Inc 2,565 53.53 % -0.30 % 0.75 1.19
6 Herbalife Ltd 1,234 12.3% 4.5% 1.10 0.80
7 111 Inc 567 -30.19 % -20.10 % 0.08 -0.03
8 Nu Skin Enterprises Inc 1,234 12.3% 4.5% 1.10 0.80
9 Zerostack Corp 1,234 12.3% 4.5% 1.10 0.80
10 Petmed Express Inc 1,234 12.3% 4.5% 1.10 0.80
11 Cosmos Health Inc 1,234 12.3% 4.5% 1.10 0.80
12 Hwh International Inc 1,234 12.3% 4.5% 1.10 0.80
Full Same-Size Peer Performance

Market cap, return, momentum, beta and Sharpe ratio for the rest of 111 Inc's same-size peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-10-01. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.

111 Inc's Profitability & Cost Structure

Trailing 12-month margins from SEC-filed financials. Operating margin is compared to the Pharmacy Services & Retail Drugstore industry median; gross margin, EBITDA margin and capital intensity are compared to the live industry average (28 companies). See the full Pharmacy Services & Retail Drugstore industry profitability benchmarks.
Metric Company Industry Difference
Gross Margin 5.76 % 21.82 % (avg) -16.1 pp
Operating Margin -0.02 % industry median -1.0 pp
EBITDA Margin -0.08 % -3.58 % (avg) +3.5 pp
Capital Intensity (Capex / Revenue) 0.04 % 1.20 % (avg) -1.2 pp

Source: CSIMarket API, trailing 12 months. SG&A and R&D as a share of revenue have limited coverage as this data is backfilled and appear only where reported. Higher capital intensity is not inherently negative; it reflects the industry's asset requirements.

111 Inc's Valuation vs Competitive Position

Valuation multiples vs the Pharmacy Services & Retail Drugstore industry average (28 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Pharmacy Services & Retail Drugstore industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 29.8x -
EV / EBITDA - 15.4x -
P/B -6.9x 3.5x -10.4x
Return on Equity 3.21 % industry aggregate -10.11 %
Return on Invested Capital 0.17 % 8.49 % (avg) -8.32 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

111 Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 202320242025
Revenue Growth 7.43 %-6.29 %-9.00 %
Operating Margin -2.34 %0.01 %-0.02 %
Return on Invested Capital 31.53 %-0.17 %0.17 %
P/E ---

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

111 Inc's Strategic Group Map

Every company in 111 Inc's industry and named-competitor list, plotted by trailing 12-month revenue growth and operating margin. 111 Inc is shown in red; its closest peers by combined growth, margin and ROIC (the Similar Growth & Profitability group above) are labeled.

Revenue Growth (TTM, %)Operating Margin (%)OCRESRXCVSCVET111 IncNUSWBASHRVCANN

Source: CSIMarket API, trailing 12 months. Extreme outlier values (from near-zero-revenue companies) are excluded from the plotted cloud but never from the highlighted company or its labeled peers.

111 Inc's BCG Growth-Share Matrix

Relative market share (vs 111 Inc's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.

Question Mark Star Dog Cash Cow Relative Market Share (vs largest competitor) Industry Revenue Growth (%) 111 Inc

111 Inc falls in the Dog quadrant: relative market share of 0.01x vs its largest competitor, in an industry growing revenue -4.1% (median, trailing 12 months).

Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.

111 Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry Low Industry HHI of 2,661 (see Industry Market Structure & Concentration above)
Barriers to Entry Lower than typical for the industry Capital intensity (capex / revenue) of 0.04 % vs industry average 1.20 % (see Profitability & Cost Structure above)
Supplier Power Not covered on this page See 111 Inc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See 111 Inc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

111 Inc's Industry Attractiveness & Competitive Strength

A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.

High Strength
Medium Strength
Low Strength
High Attractiveness
Invest / Grow
Invest / Grow
Selective
Medium Attractiveness
Invest / Grow
Selective 111 Inc
Harvest
Low Attractiveness
Selective
Harvest
Harvest / Divest

111 Inc falls in the Medium attractiveness / Medium strength cell: Selective.

Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.

111 Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

  • Latest-quarter revenue run-rate is accelerating (+311.1% annualized vs trailing 12 months).

Weaknesses

  • Return on equity 10.1 points below the industry aggregate.
  • Underperforming the U.S.A. 500 over the trailing 12 months.
  • Low relative market share vs the industry leader (0.01x).

Opportunities

No rule matched.

Threats

No rule matched.

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

111 Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
111 Inc 0.26 1.09 - 5.55
Jd com Inc 0.45 1.22 0.20 1.83
Zto Express cayman Inc 0.44 1.49 0.17 0.52
Huya inc 0.40 2.84 - 0.94

Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

111 Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
111 Inc Q4 2025-12.7 %-12.7 %--
Jd com Inc Q4 2025+13.1 %+13.1 %-45.9 %-45.9 %
Zto Express cayman Inc Q4 2025+11.0 %+11.0 %+7.5 %+7.5 %
Huya inc Q4 2025+7.1 %+7.1 %--
PEERS TOTAL+12.7 %+12.7 %-37.3 %-37.3 %

Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

111 Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
111 Inc Q4 2025-9.0 %-9.0 %-69.5 %-69.5 %
Jd com Inc Q4 2025+17.7 %+17.7 %+52.5 %+52.5 %
Zto Express cayman Inc Q4 2025+25.8 %+25.8 %+29.4 %+29.4 %
Huya inc Q4 2025+11.5 %+11.5 %-9.7 %-9.7 %

111 Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
111 Inc ---47.0511.85
Jd com Inc 3.33%5.40%10.28%46.6011.52
Zto Express cayman Inc 9.98%13.20%13.68%37.11907.19
Huya inc ---26.52-

ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

111 Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
111 Inc -0.32-92.32-
Jd com Inc 4.140.440.0216.412.47
Zto Express cayman Inc 1.742.340.00-1.68
Huya inc -0.58--0.75
PEERS AVERAGE21.070.5022.552.29

P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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