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Verve Therapeutics Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Verve Therapeutics Inc (VERV) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q1 2025
Competitors
162
Named by the company
Peer Group Market Share
1.64 %
vs 0.31 % a year ago
Revenue Growth Y/Y
479.03 %
Peers: 6.51 %
Net Margin
-94.11 %
Peers: -56.22 %

Key Findings: Verve Therapeutics Inc vs Its Competitors

  • TTM: Trailing 12-month revenue of 60M vs 11,921M combined for its competitors (0.5% combined share).
  • Trending: Latest-quarter revenue run-rate is accelerating (+121.3% annualized vs trailing 12 months), vs decelerating (-33.6%) for its tracked peer group.
  • Growth: Verve Therapeutics Inc generated 479.0% revenue growth year over year in Q1 2025, vs 6.5% for its competitors combined.
  • Profitability: Its -94.1% net margin compares with -56.2% for the peer group.
  • Peer revenue share: Verve Therapeutics Inc accounted for 1.6% of combined revenue among its tracked peer group, up from 0.3% a year earlier.
  • Peer differentiation: Revenue per employee of $2.84M compares with $0.74M for the peer group (3.8x).

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

VERV Sales vs. its Competitors, Q1 2025

Verve Therapeutics Inc reported revenue growth of 479.03 % year on year in Q1 2025, above its competitors' combined revenue growth of 6.51 %.

With a net margin of -94.11 %, Verve Therapeutics Inc reported lower profitability than its competitors (-56.22 %).

Verve Therapeutics Inc generated 1.64 % of the combined sales of its peer group, up from 0.31 % a year earlier.

API endpoints for this dataset

https://api.csimarket.com/api/v1/companies/VERV/competitors
https://api.csimarket.com/api/v1/companies/VERV/relationships
https://api.csimarket.com/api/v1/companies/VERV/similar
Programmatic access for models, analytics, and integration workflows.
Explore the Financial Data API

Verve Therapeutics Inc vs. its Competitors, Q1 2025

Revenue growth, year on year

Verve Therapeutics Inc +479.0 %
Competitors combined +6.5 %

Net margin

Verve Therapeutics Inc -94.1 %
Competitors combined -56.2 %

Revenue run-rate vs trailing 12 months

Verve Therapeutics Inc +121.3 %
Competitors combined -33.6 %

TTM net margin

Verve Therapeutics Inc -303.6 %
Competitors combined -3.9 %

TTM = trailing twelve months. Run-rate annualizes the latest quarter (×4) and compares it to TTM. In millions of $. High-Confidence Competitors are named as a competitor directly in Verve Therapeutics Inc reports; Similar-Size Competitors are the closest peers by market-cap rank within the same industry; Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC, all independent of the competitor list.

Competitor Financial Benchmarking - TTM Commercial

TTM revenue, latest-quarter run-rate and net income/margin benchmarked across Verve Therapeutics Inc and its 4 competitor groupings. Available under Commercial License.

Entity TTM Revenue Latest Q ×4 Rev Run-rate vs TTM TTM Net Income TTM Net Margin
Verve Therapeutics Inc $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitors combined $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
High-Confidence Competitors (96) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitor Financial Benchmarking

TTM revenue, run-rate and net margin benchmarking across Verve Therapeutics Inc's competitor groups requires a Commercial License.

For context: the Major Pharmaceutical Preparations industry grew revenue 9.0% year over year, combined, vs 479.0% for Verve Therapeutics Inc. Verve Therapeutics Inc's share of combined industry revenue moved from 0.00% to 0.01%, a gain of 0.01 percentage points.

Verve Therapeutics Inc's Competitor Quality Breadth

Group definitions: see Methodology: Performance Group Definitions.

Entity Profitable Expanding Above Industry Growth Distressed
Verve Therapeutics Inc - Yes Yes No
Competitors combined (46) 38% 65% 50% 54%
High-Confidence Competitors (107) 68% 62% 48% 57%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

Market Share of the Peer Group, Q1 2025

1.6%market share
  • Verve Therapeutics Inc1.6%
  • Competitors combined98.4%

Share of combined quarterly revenue of Verve Therapeutics Inc and its 162 competitors.

See Verve Therapeutics Inc's full market share breakdown »

VERV Stock Performance relative to its Competitors

VERV Competitors (weighted) Percent change over the selected range

Verve Therapeutics Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
30.6%beat U.S.A. 500
Competitors Combined
(11 of 36)
41.1%beat U.S.A. 500
High-Confidence
(37 of 90)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Verve Therapeutics Inc 65.40 % Outperformed
Competitors combined (36) 40.4% 63.2%
High-Confidence Competitors (90) 40.4% 63.2%
Similar-Size Competitors (0) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Verve Therapeutics Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

VERV Stock Performance relative to High-Confidence Competitors

VERV High-Confidence Competitors (equal-weighted, 112) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Tango Therapeutics Inc 282.9% Outperformed
2 Avadel Pharmaceuticals Plc 282.9% Outperformed
3 Apellis Pharmaceuticals Inc 282.9% Outperformed
4 Kalvista Pharmaceuticals Inc 282.9% Outperformed
5 Precision Biosciences Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Verve Therapeutics Inc's best-performing competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Verve Therapeutics Inc's Comment on Competition and Industry Peers

The company operates in the biotechnology and biopharmaceutical industries, focusing on cardiovascular disease (CVD). It faces competition from major pharmaceutical, specialty pharmaceutical, and biotechnology companies, as well as academic institutions, governmental agencies, and public and private research organizations. Competitors often possess greater financial resources and expertise in research and development, manufacturing, clinical trials, regulatory approvals, and marketing. Industry consolidation through mergers and acquisitions may concentrate resources among fewer competitors. Smaller or early-stage companies can also be significant competitors, particularly through collaborations with larger firms. Competition extends to securing qualified personnel, clinical trial sites, patient enrollment, and complementary technologies. Key factors influencing competitiveness in developing treatments for atherosclerotic cardiovascular disease (ASCVD) include efficacy, safety, convenience, price, generic competition, and reimbursement availability.

Publicly Traded Peers of Verve Therapeutics Inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Verve Therapeutics Inc 988.30 59.61 -181.01 21
United Therapeutics Corporation 26,602.70 3,154.50 1,310.90 1,400
Alnylam Pharmaceuticals Inc 21,626.73 5,013.24 2,724.24 2,500
Bridgebio Pharma Inc 15,299.15 945.54 -573.79 839
Apellis Pharmaceuticals Inc 5,392.33 1,105.28 133.27 739
Crispr Therapeutics Ag 4,651.31 25.17 -456.14 201
SUBTOTAL 92,554.98 11,430.05 -991.33 15,318
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Sources: see Methodology: Peer & Competitor Identification, Sourcing.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Verve Therapeutics Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Verve Therapeutics Inc's Competitors Named by the Company

Competitive relationships identified from Verve Therapeutics Inc reports and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Takeda Pharmaceutical Company Limited Company report 85% 2022 to 2026 3
Pfizer Inc Company report 85% 2022 to 2026 3
Passage Bio Inc Company report 85% 2022 to 2026 3
Biogen Inc Company report 85% 2022 to 2026 3
Abbvie Inc Company report 85% 2022 to 2026 3
Petvivo Holdings Inc Company report 85% 2022 to 2026 3
Regencell Bioscience Holdings Limited Company report 85% 2022 to 2026 3
Agentix Corp Company report 85% 2022 to 2026 3
Intensity Therapeutics Inc Company report 85% 2022 to 2026 3
Sagimet Biosciences inc Company report 85% 2022 to 2026 3
Mangoceuticals Inc Company report 85% 2022 to 2026 3
Fibrobiologics Inc Company report 85% 2022 to 2026 3
Monopar Therapeutics Inc Company report 85% 2022 to 2026 3
Acumen Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Crispr Therapeutics Ag Company report 85% 2022 to 2026 3
Puma Biotechnology Inc Company report 85% 2022 to 2026 3
Corbus Pharmaceuticals Holdings Inc Company report 85% 2022 to 2026 3
Novartis Ag Company report 85% 2022 to 2026 3
Johnson and Johnson Company report 85% 2022 to 2026 3
Merck and Co Inc Company report 85% 2022 to 2026 3
Halozyme Therapeutics Inc Company report 85% 2022 to 2026 3
Inventiva S a Company report 85% 2022 to 2026 3
Denali Therapeutics Inc Company report 85% 2022 to 2026 3
Regeneron Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Neurosense Therapeutics Ltd Company report 85% 2022 to 2026 3
Roche Holding AG Company report 85% 2022 to 2026 3
Intellia Therapeutics Inc Company report 85% 2022 to 2026 3
Alnylam Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Voyager Therapeutics Inc Company report 85% 2022 to 2026 3
Shuttle Pharmaceuticals Holdings Inc Company report 85% 2022 to 2026 3
Bristol-Myers Squibb Company report 85% 2022 to 2026 3
Fusion Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Beone Medicines Ltd Company report 85% 2022 to 2026 3
Bicycle Therapeutics Plc Company report 85% 2022 to 2026 3
Compass Therapeutics Inc Company report 85% 2022 to 2026 3
Contineum Therapeutics Inc Company report 85% 2022 to 2026 3
Redwoods Acquisition Corp Company report 85% 2022 to 2026 3
Definium Therapeutics Inc Company report 85% 2022 to 2026 3
Nyxoah Sa Company report 85% 2022 to 2026 3
Janux Therapeutics Inc Company report 85% 2022 to 2026 3
Abivax Sa Company report 85% 2022 to 2026 3
Nuvation Bio Inc Company report 85% 2022 to 2026 3
BGNE Company report 85% 2022 to 2026 3
Coya Therapeutics Inc Company report 85% 2022 to 2026 3
Protagonist Therapeutics inc Company report 85% 2022 to 2026 3
Cytosorbents Corporation Company report 85% 2022 to 2026 3
MNMD Company report 85% 2022 to 2026 3
Silexion Therapeutics Corp Company report 85% 2022 to 2026 3
Innate Pharma Sa Company report 85% 2022 to 2026 3
Bicara Therapeutics Inc Company report 85% 2022 to 2026 3
Can fite Biopharma Ltd Company report 85% 2022 to 2026 3
Reshape Lifesciences Inc Company report 85% 2022 to 2026 3
Novo Nordisk A Company report 85% 2022 to 2026 3
Actinium Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Palatin Technologies Inc Company report 85% 2022 to 2026 3
Maia Biotechnology Inc Company report 85% 2022 to 2026 3
Curanex Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Sana Biotechnology Inc Company report 85% 2022 to 2026 3
Altimmune inc Company report 85% 2022 to 2026 3
Prime Medicine Inc Company report 85% 2022 to 2026 3
Outlook Therapeutics Company report 85% 2022 to 2026 3
Generation Bio Co Company report 85% 2022 to 2026 3
Igm Biosciences Inc Company report 85% 2022 to 2026 3
Ocular Therapeutix Company report 85% 2022 to 2026 3
REGENXBIO Company report 85% 2022 to 2026 3
Jupiter Neurosciences Inc Company report 85% 2022 to 2026 3
Cytomx Therapeutics Inc Company report 85% 2022 to 2026 3
Journey Medical Corp Company report 85% 2022 to 2026 3
Kodiak Sciences Company report 85% 2022 to 2026 3
Akero Therapeutics Inc Company report 85% 2022 to 2026 3
Bright Minds Biosciences Inc Company report 85% 2022 to 2026 3
Opthea Company report 85% 2022 to 2026 3
Skye Bioscience Inc Company report 85% 2022 to 2026 3
Vincerx Pharma Inc Company report 85% 2022 to 2026 3
Macrogenics Inc Company report 85% 2022 to 2026 3
Cytokinetics Incorporated Company report 85% 2022 to 2026 3
Elicio Therapeutics Inc Company report 85% 2022 to 2026 3
Spyre Therapeutics Inc Company report 85% 2022 to 2026 3
Qsam Biosciences Inc Company report 85% 2022 to 2026 3
Lumos Pharma Inc Company report 85% 2022 to 2026 3
Peak Bio Inc Company report 85% 2022 to 2026 3
Aclaris Therapeutics Inc Company report 85% 2022 to 2026 3
Point Pharmaceuticals Company report 85% 2022 to 2026 3
Opus Genetics Inc Company report 85% 2022 to 2026 3
Mannkind Corporation Company report 85% 2022 to 2026 3
Ngm Biopharmaceuticals Inc Company report 85% 2022 to 2026 3
Molecular Partners Ag Company report 85% 2022 to 2026 3
OCUP Company report 85% 2022 to 2026 3
Gossamer Bio Inc Company report 85% 2022 to 2026 3
Xeris Biopharma Holdings Inc Company report 85% 2022 to 2026 3
Immunome Inc Company report 85% 2022 to 2026 3
Biorestorative Therapies Inc Company report 85% 2022 to 2026 3
Invivyd Inc Company report 85% 2022 to 2026 3
Abvc Biopharma Inc Company report 85% 2022 to 2026 3
Sutro Biopharma Inc Company report 85% 2022 to 2026 3
4D Molecular Therapeutics Company report 85% 2022 to 2026 3
Better Therapeutics Inc Company report 85% 2022 to 2026 3
Hoffmann-La Roche Ltd. Company report 85% 2022 to 2026 3
UCB Company report 85% 2022 to 2026 3
Bayer Company report 85% 2022 to 2026 3
Sab Biotherapeutics Inc Company report 85% 2022 to 2026 3
Scholar Rock Company report 85% 2022 to 2026 3
Vaxxinity Inc Company report 85% 2022 to 2026 3
Graybug Vision Company report 85% 2022 to 2026 3
Janssen Company report 85% 2022 to 2026 3
Inflarx N V Company report 85% 2022 to 2026 3
Fresh Tracks Therapeutics Inc Company report 85% 2022 to 2026 3
Alector Inc Company report 85% 2022 to 2026 3
Exagen Inc Company report 85% 2022 to 2026 3
Anavex Life Sciences Corp Company report 85% 2022 to 2026 3
Agios Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Viracta Therapeutics Inc Company report 85% 2022 to 2026 3
Harmony Biosciences Holdings inc Company report 85% 2022 to 2026 3
Acceleron Pharma inc Company report 85% 2022 to 2026 3
Mirati Therapeutics Inc Company report 85% 2022 to 2026 3
Vanda Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Generic Pharmaceuticals Company report 85% 2022 to 2026 3
Sanofi Company report 85% 2022 to 2026 3
Gilead Sciences Inc Company report 85% 2022 to 2026 3
Editas Medicine Inc Company report 85% 2022 to 2026 3
Springworks Therapeutics Inc Company report 85% 2022 to 2026 3
Incannex Healthcare Inc Company report 85% 2022 to 2026 3
Electrocore Inc Company report 85% 2022 to 2026 3
Vistagen Therapeutics Inc Company report 85% 2022 to 2026 3
Moonlake Immunotherapeutics Company report 85% 2022 to 2026 3
Edesa Biotech Inc Company report 85% 2022 to 2026 3
Alzamend Neuro Inc Company report 85% 2022 to 2026 3
Sangamo Therapeutics Inc Company report 85% 2022 to 2026 3
Incyte Corporation Company report 85% 2022 to 2026 3
Esperion Therapeutics Inc Company report 85% 2022 to 2026 3
Bluebird Bio Inc Company report 85% 2022 to 2026 3
Gsk Plc Company report 85% 2022 to 2026 3
Precigen Inc Company report 85% 2022 to 2026 3
Affimed N v Company report 85% 2022 to 2026 3
Precision Biosciences Inc Company report 85% 2022 to 2026 3
Bolt Biotherapeutics Inc Company report 85% 2022 to 2026 3
Vertex Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Abbott Laboratories Company report 85% 2022 to 2026 3
Arcus Biosciences Inc Company report 85% 2022 to 2026 3
United Therapeutics Corporation Company report 85% 2022 to 2026 3
Bellicum Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Humanigen Inc Company report 85% 2022 to 2026 3
Teva Pharmaceutical Industries Limited Company report 85% 2022 to 2026 3
Kiniksa Pharmaceuticals International Plc Company report 85% 2022 to 2026 3
Nkarta Inc Company report 85% 2022 to 2026 3
Ultragenyx Pharmaceutical Inc Company report 85% 2022 to 2026 3
Amgen Inc Company report 85% 2022 to 2026 3
Theravance Biopharma inc Company report 85% 2022 to 2026 3
Jazz Pharmaceuticals Plc Company report 85% 2022 to 2026 3
Lexicon Pharmaceuticals Inc Company report 85% 2022 to 2026 3
Sage Therapeutics Inc Company report 85% 2022 to 2026 3
Xencor Inc Company report 85% 2022 to 2026 3
Horizon Therapeutics Public Limited Company Company report 85% 2022 to 2026 3
Argenx Se Company report 85% 2022 to 2026 3
Organon and Co Company report 85% 2022 to 2026 3
Tiziana Life Sciences Ltd Company report 85% 2022 to 2026 3
Astrazeneca Plc Company report 85% 2022 to 2026 3
Wave Life Sciences Ltd Company report 85% 2022 to 2026 3
Galapagos Nv Company report 85% 2022 to 2026 3
Viatris Inc Company report 85% 2022 to 2026 3
Biohaven Ltd Company report 85% 2022 to 2026 3
Nektar Therapeutics Company report 85% 2022 to 2026 3
Competitor Evidence Detail

Company report basis, confidence, active dates and source counts for Verve Therapeutics Inc's named competitors require a Commercial License.

Methodology: see Methodology: Peer & Competitor Identification, Sourcing.

Verve Therapeutics Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Bridgebio Pharma Inc Reportable 100.00 % - -
Apellis Pharmaceuticals Inc Reportable Segment Aggregation Before Other Operating Segment 100.00 % - -
Avadel Pharmaceuticals Plc Reportable 100.00 % - -
Intellia Therapeutics Inc Development of Gene Editing Based Therapies 100.00 % - -
Precigen Inc Reportable 100.00 % - -

Source: operating segment revenue as reported in each company's reports (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Verve Therapeutics Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Verve Therapeutics Inc 988 2,838,714 -8,619,333
United Therapeutics Corporation 26,603 2,253,214 936,357
Alnylam Pharmaceuticals Inc 21,627 2,005,297 1,089,696
Bridgebio Pharma Inc 15,299 1,126,985 -683,899
Apellis Pharmaceuticals Inc 5,392 1,495,643 180,337
Crispr Therapeutics Ag 4,651 125,234 -2,269,328
PEERS TOTAL 91,567 743,311 -52,973
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Verve Therapeutics Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent report. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
United Therapeutics Corporation UNITED STATES 97.12 % Non-US 2.88 % -
Ultragenyx Pharmaceutical Inc North America 52.02 % Latin America 22.54 % EMEA 21.39 %
23andme Holding Co United States 90.26 % United Kingdom 5.67 % Canada 5.30 %

Source: revenue geography as reported in each company's reports (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

Verve Therapeutics Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 491 companies in Verve Therapeutics Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Verve Therapeutics Inc ranks #0 of 491 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 983, indicating a unconcentrated market structure (see Methodology: Market Structure & Concentration).

Rank Company Market Cap Industry Share
1 Eli Lilly And Company 1,267,410 23.79 %
2 Johnson and Johnson 688,169 12.92 %
3 Abbvie Inc 519,284 9.75 %
4 Merck and Co Inc 364,892 6.85 %
5 Novartis Ag 1,234 5.2%
6 Abbott Laboratories 1,234 5.2%
7 Novo Nordisk A 1,234 5.2%
8 Pfizer Inc 1,234 5.2%
9 Astrazeneca Plc 1,234 5.2%
10 Vertex Pharmaceuticals Inc 1,234 5.2%
0 Verve Therapeutics Inc 988 0.00 %
Full Industry Market Structure

Market cap and industry share for the rest of Verve Therapeutics Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2025-07-24.

Verve Therapeutics Inc's Profitability & Cost Structure

Trailing 12-month margins from SEC-filed financials. Operating margin is compared to the Major Pharmaceutical Preparations industry median; gross margin, EBITDA margin and capital intensity are compared to the live industry average (446 companies). See the full Major Pharmaceutical Preparations industry profitability benchmarks.
Metric Company Industry Difference
Gross Margin 0.00 % 37.93 % (avg) -37.9 pp
Operating Margin - industry median -
EBITDA Margin - -6.39 % (avg) -
Capital Intensity (Capex / Revenue) 7.59 % 7.56 % (avg) +0.0 pp

Source: CSIMarket API, trailing 12 months. SG&A and R&D as a share of revenue have limited coverage as this data is backfilled and appear only where reported. Higher capital intensity is not inherently negative; it reflects the industry's asset requirements.

Verve Therapeutics Inc's Valuation vs Competitive Position

Valuation multiples vs the Major Pharmaceutical Preparations industry average (446 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 26.4x -
EV / EBITDA - 15.3x -
P/B 1.2x 4.2x -3.0x
Return on Equity -35.82 % industry aggregate -51.01 %
Return on Invested Capital -18.64 % -9.78 % (avg) -8.86 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Verve Therapeutics Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in company reports.
Metric 2021202220232024
Revenue Growth ---174.98 %
Operating Margin ----
Return on Invested Capital --18.11 %-19.86 %-19.36 %
P/E ----

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Verve Therapeutics Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 983 (see Industry Market Structure & Concentration above)
Barriers to Entry Moderate, in line with the industry Capital intensity (capex / revenue) of 7.59 % vs industry average 7.56 % (see Profitability & Cost Structure above)

Note: see Methodology: Porter's Five Forces. Supplier power and buyer power are covered on Verve Therapeutics Inc's dedicated Suppliers and Customers pages, not here.

Verve Therapeutics Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

  • Latest-quarter revenue run-rate is accelerating (+121.3% annualized vs trailing 12 months).
  • Outperforming the U.S.A. 500 over the trailing 12 months.

Weaknesses

  • Return on equity 51.0 points below the industry aggregate.

Opportunities

  • A meaningful share of competitors (54.30 %) show financial-distress signals, a possible opening to gain share.

Threats

  • Tracked peer group's revenue run-rate is broadly decelerating (-33.6% annualized).

Methodology: see Methodology: SWOT Analysis.

Verve Therapeutics Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Verve Therapeutics Inc 3.20 12.38 - 0.09
United Therapeutics Corporation 2.58 5.86 - 0.43
Alnylam Pharmaceuticals Inc 1.07 2.82 0.59 0.85
Bridgebio Pharma Inc 1.23 1.74 - 0.67
Apellis Pharmaceuticals Inc 1.58 3.49 1.36 1.09
Crispr Therapeutics Ag 2.24 16.26 0.25 0.01
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Verve Therapeutics Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Verve Therapeutics Inc Q1 2025+479.0 %+152.1 %--
United Therapeutics CorporationQ2 2026-1.9 %+0.2 %+7.6 %+21.1 %
Alnylam Pharmaceuticals Inc Q3 2026+16.7 %+12.9 %+640.5 %+1,217.6 %
Bridgebio Pharma Inc Q3 2026+192.6 %+44.9 %--
Apellis Pharmaceuticals Inc Q1 2026+60.9 %+34.2 %--
Crispr Therapeutics AgQ3 2026+1,325.1 %+24.4 %--
PEERS TOTAL+26.3 %+16.3 %--
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Verve Therapeutics Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Verve Therapeutics Inc Q1 2025--+182.7 %-11.8 %
United Therapeutics CorporationQ2 2026+13.6 %-25.4 %+73.6 %+7.1 %
Alnylam Pharmaceuticals Inc Q3 2026+83.4 %+21.3 %+475.1 %+101.4 %
Bridgebio Pharma Inc Q3 2026+211.6 %+35.9 %-89.9 %-34.5 %
Apellis Pharmaceuticals Inc Q1 2026-14.5 %---
Crispr Therapeutics AgQ3 2026--+459.5 %-36.1 %
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Verve Therapeutics Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Verve Therapeutics Inc -----
United Therapeutics Corporation17.98%19.53%20.18%9.932.39
Alnylam Pharmaceuticals Inc 46.08%63.14%159.72%5.4812.28
Bridgebio Pharma Inc ---3.881.24
Apellis Pharmaceuticals Inc 13.20%17.94%39.71%3.240.15
Crispr Therapeutics Ag-----
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Verve Therapeutics Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Verve Therapeutics Inc -16.58--2.09
United Therapeutics Corporation20.858.432.03126.624.16
Alnylam Pharmaceuticals Inc 8.004.31-82.236.00
Bridgebio Pharma Inc -16.18-17.18-
Apellis Pharmaceuticals Inc 39.454.88-114.9713.00
Crispr Therapeutics Ag-184.78--2.82
PEERS AVERAGE-8.1049.716.31
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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