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Sagimet Biosciences Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Sagimet Biosciences Inc (SGMT) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q2 2026
Competitors Tracked
80
Publicly traded peers
Peer Group Market Share
-
Share of combined sales, Q2 2026
Revenue Growth Y/Y
-
Peers: 22.18 %
Net Margin
-
Peers: -4.04 %

Key Findings: Sagimet Biosciences Inc vs Its Competitors

  • Scale: Sagimet Biosciences Inc ranks #188 of 544 companies by market capitalization in the Major Pharmaceutical Preparations industry, holding 0.0% of industry market cap.

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/SGMT/competitors
https://api.csimarket.com/api/v1/companies/SGMT/relationships
https://api.csimarket.com/api/v1/companies/SGMT/similar
Programmatic access for models, analytics, and integration workflows.

Sagimet Biosciences Inc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Sagimet Biosciences inc - - - Yes
Competitors combined (80) 31% 68% 54% 41%
High-Confidence Competitors (20) 69% 71% 36% 35%
Similar-Size Competitors (10) 43% 43% 43% 13%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

SGMT Stock Performance relative to its Competitors

SGMT Competitors (weighted) Percent change over the selected range

Sagimet Biosciences Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
41.9%beat U.S.A. 500
Competitors Combined
(31 of 74)
76.5%beat U.S.A. 500
High-Confidence
(13 of 17)
50%beat U.S.A. 500
Similar-Size
(5 of 10)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Sagimet Biosciences inc 30.00 % Outperformed
Competitors combined (74) 40.4% 63.2%
High-Confidence Competitors (17) 40.4% 63.2%
Similar-Size Competitors (10) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Sagimet Biosciences Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

SGMT Stock Performance relative to High-Confidence Competitors

SGMT High-Confidence Competitors (equal-weighted, 22) Percent change over the selected range

SGMT Stock Performance relative to Similar-Size Competitors

SGMT Similar-Size Competitors (equal-weighted, 10) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Adlai Nortye Ltd 282.9% Outperformed
2 Praxis Precision Medicines Inc 282.9% Outperformed
3 Spyre Therapeutics Inc 282.9% Outperformed
4 Regulus Therapeutics Inc 282.9% Outperformed
5 Nurix Therapeutics Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Sagimet Biosciences Inc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Sagimet Biosciences Inc's Comment on Competition and Industry Peers

The company operates in a highly competitive biopharmaceutical industry with numerous competitors developing compounds targeting similar indications. Notable competitors include Madrigal Pharmaceuticals, Inc., which has received FDA and European Commission approvals for resmetirom (Rezdiffra) for treating MASH, and Novo Nordisk A/S, which obtained FDA approval for Wegovy (semaglutide) for MASH treatment. Other multinational pharmaceutical and biotechnology companies in the competitive landscape include Altimmune, Inc., AstraZeneca, Boehringer Ingelheim, Zealand Pharma, Eli Lilly and Company, Galmed Pharmaceuticals Ltd., Gilead Sciences, Inc., GSK plc (which acquired Boston Pharmaceuticals in 2025), Inventiva S.A., Merck & Co., Inc., Pfizer Inc., Roche Holdings, Inc. (which acquired 89bio, Inc. in 2025), Terns Pharmaceuticals, Inc., Viking Therapeutics, Inc., and Zydus Therapeutics Inc. The company also acknowledges that smaller or earlier-stage companies, particularly through collaborations, may represent significant competition. Key factors influencing competition include efficacy, safety, tolerability, dosing convenience, price, generic competition, and reimbursement. The company’s drug candidate denifanstat may compete with other drug classes and mechanisms but could be used alone or in combination due to its complementary mechanism. Additionally, the company holds a license agreement with Ascletis Pharma, a biotechnology company based in Hangzhou, China.

Publicly Traded Peers of Sagimet Biosciences inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Sagimet Biosciences inc 527.96 - -47.08 16
Eli Lilly And Company 1,058,837.89 79,665.80 26,711.20 50,000
Novartis Ag 287,150.40 56,674.00 13,967.00 75,267
Gilead Sciences Inc 189,197.03 30,457.00 -3,240.00 17,000
Pfizer Inc 163,675.28 63,696.00 4,370.00 75,000
Vertex Pharmaceuticals Inc 134,661.38 12,587.20 4,405.20 405
SUBTOTAL 2,126,271.78 275,514.99 43,370.64 251,023
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Sources: Sagimet Biosciences inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Sagimet Biosciences inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Sagimet Biosciences Inc's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Pfizer Inc. Named by the company 85% 2022 to 2026 3
Altimmune, Inc. Named by the company 85% 2022 to 2026 3
Intercept Pharmaceuticals, Inc. Named by the company 85% 2022 to 2026 3
Novartis AG Named by the company 85% 2022 to 2026 3
Viking Therapeutics, Inc. Named by the company 85% 2022 to 2026 3
89bio, Inc. Named by the company 85% 2022 to 2026 3
Gilead Sciences, Inc. Named by the company 85% 2022 to 2026 3
NGM Biopharmaceuticals, Inc. Named by the company 85% 2022 to 2026 3
Inventiva S a Named by the company 85% 2022 to 2026 3
Eli Lilly and Company Named by the company 85% 2022 to 2026 3
Madrigal Pharmaceuticals, Inc. Named by the company 85% 2022 to 2026 3
Akero Therapeutics, Inc. Named by the company 85% 2022 to 2026 3
Terns Pharmaceuticals, Inc. Named by the company 85% 2022 to 2026 3
Galmed Pharmaceuticals Ltd. Named by the company 85% 2022 to 2026 3
Merck & Co., Inc. Named by the company 85% 2022 to 2026 3
Zydus Therapeutics Inc. Named by the company 85% 2022 to 2026 3
Bristol-Myers Squibb Company Named by the company 85% 2022 to 2026 3
Boehringer Ingelheim Named by the company 85% 2022 to 2026 3
Roche Holdings, Inc. Named by the company 85% 2022 to 2026 3
Ascletis Pharma Named by the company 85% 2022 to 2026 3
Novo Nordisk A/S Named by the company 85% 2022 to 2026 3
Zealand Pharma Named by the company 85% 2022 to 2026 3
Boston Pharmaceuticals Named by the company 85% 2022 to 2026 3
GSK plc Named by the company 85% 2022 to 2026 3
NorthSea Therapeutics B.V. Named by the company 85% 2022 to 2026 3
Rafael Holdings Inc Named by the company 85% 2022 to 2026 3
AstraZeneca Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for Sagimet Biosciences Inc's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

Sagimet Biosciences Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Eli Lilly And Company Reportable 100.00 % - -
Pfizer Inc U.S. Commercial Division 52.92 % International Commercial Division 36.88 % Global Hospital and Biosimilars Division 7.72 %
Vertex Pharmaceuticals Inc Pharmaceuticals 100.00 % - -
Madrigal Pharmaceuticals Inc Reportable 100.00 % - -
Protagonist Therapeutics inc Single reportable segment 100.00 % - -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Sagimet Biosciences Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Sagimet Biosciences inc 528 - -2,942,438
Eli Lilly And Company 1,058,838 1,593,316 534,224
Novartis Ag 287,150 752,973 185,566
Gilead Sciences Inc 189,197 1,791,588 -190,588
Pfizer Inc 163,675 849,280 58,267
Vertex Pharmaceuticals Inc 134,661 31,079,506 10,877,037
PEERS TOTAL 2,125,744 1,097,639 172,974
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Sagimet Biosciences Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Eli Lilly And Company United States 61.21 % Europe 18.42 % Rest of world 14.00 %
Gilead Sciences Inc United States 70.78 % Europe 16.44 % Rest of World 12.77 %
Pfizer Inc United States 58.91 % International Developed Markets 24.90 % International Emerging Markets 16.19 %
Vertex Pharmaceuticals Inc United States 61.68 % Europe 29.33 % Other Countries Outside of the United States and Europe 8.99 %
Ptc Therapeutics inc All Other Countries Other Than Russia Brazil and United States 16.36 % - -

Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

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Sagimet Biosciences Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 498 companies in Sagimet Biosciences Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Sagimet Biosciences Inc ranks #188 of 498 companies by market capitalization in its industry, holding 0.01 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 823, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Eli Lilly And Company 1,058,838 19.26 %
2 Johnson and Johnson 663,585 12.07 %
3 Beone Medicines Ltd 552,468 10.05 %
4 Abbvie Inc 471,582 8.58 %
5 Merck and Co Inc 1,234 5.2%
6 Novartis Ag 1,234 5.2%
7 Abbott Laboratories 1,234 5.2%
8 Novo Nordisk A 1,234 5.2%
9 Pfizer Inc 1,234 5.2%
10 Vertex Pharmaceuticals Inc 1,234 5.2%
188 Sagimet Biosciences inc 528 0.01 %
Full Industry Market Structure

Market cap and industry share for the rest of Sagimet Biosciences Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-28.

Sagimet Biosciences Inc's Same-Size Peers & Stock Performance

Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.
Rank Company Market Cap TTM Return 3M Momentum Beta Sharpe (1Y)
183 Aquestive Therapeutics Inc 594 -12.26 % 10.41 % 1.36 0.21
184 Cytomx Therapeutics Inc 589 -7.39 % -31.15 % 1.74 0.31
185 Canton Strategic Holdings Inc 583 -13.75 % -11.62 % 0.86 0.32
186 Opus Genetics Inc 562 172.09 % 10.64 % 0.98 1.69
187 Altimmune inc 1,234 12.3% 4.5% 1.10 0.80
188 Sagimet Biosciences inc 528 29.97 % 21.94 % 2.06 0.74
189 Evolus Inc 1,234 12.3% 4.5% 1.10 0.80
190 Puma Biotechnology Inc 1,234 12.3% 4.5% 1.10 0.80
191 Capricor Therapeutics inc 1,234 12.3% 4.5% 1.10 0.80
192 Kamada Ltd 1,234 12.3% 4.5% 1.10 0.80
193 Arvinas Inc 1,234 12.3% 4.5% 1.10 0.80
Full Same-Size Peer Performance

Market cap, return, momentum, beta and Sharpe ratio for the rest of Sagimet Biosciences Inc's same-size peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-09-28. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.

Sagimet Biosciences Inc's Valuation vs Competitive Position

Valuation multiples vs the Major Pharmaceutical Preparations industry average (341 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 25.1x -
EV / EBITDA - 17.3x -
P/B 2.6x 4.5x -1.9x
Return on Equity -31.96 % industry aggregate -49.21 %
Return on Invested Capital -17.84 % -2.95 % (avg) -14.89 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Sagimet Biosciences Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 202320242025
Revenue Growth ---
Operating Margin ---
Return on Invested Capital --15.41 %-22.76 %
P/E ---

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Sagimet Biosciences Inc's BCG Growth-Share Matrix

Relative market share (vs Sagimet Biosciences Inc's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.

Question Mark Star Dog Cash Cow Relative Market Share (vs largest competitor) Industry Revenue Growth (%) Sagimet Biosciences Inc

Sagimet Biosciences Inc falls in the Dog quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 8.0% (median, trailing 12 months).

Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.

Sagimet Biosciences Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 823 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Sagimet Biosciences Inc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Sagimet Biosciences Inc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Sagimet Biosciences Inc's Industry Attractiveness & Competitive Strength

A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.

High Strength
Medium Strength
Low Strength
High Attractiveness
Invest / Grow
Invest / Grow
Selective
Medium Attractiveness
Invest / Grow
Selective
Harvest
Low Attractiveness
Selective
Harvest
Harvest / Divest Sagimet Biosciences Inc

Sagimet Biosciences Inc falls in the Low attractiveness / Low strength cell: Harvest / Divest.

Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.

Sagimet Biosciences Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

  • Outperforming the U.S.A. 500 over the trailing 12 months.

Weaknesses

  • Return on equity 49.2 points below the industry aggregate.
  • Low relative market share vs the industry leader (0.00x).
  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

  • A meaningful share of tracked competitors (40.50 %) show financial-distress signals, a possible opening to gain share.

Threats

No rule matched.

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Sagimet Biosciences Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Sagimet Biosciences inc 14.49 23.54 - -
Eli Lilly And Company 0.20 1.48 1.59 0.66
Novartis Ag 0.42 1.12 0.02 0.51
Gilead Sciences Inc - 1.54 1.27 0.55
Pfizer Inc 0.04 1.24 0.71 0.31
Vertex Pharmaceuticals Inc 1.34 2.85 - 0.48
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Sagimet Biosciences Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Sagimet Biosciences inc Q2 2026----
Eli Lilly And CompanyQ2 2026+47.7 %+16.0 %+25.3 %-4.1 %
Novartis AgQ4 2025+9.6 %+9.6 %+17.0 %+17.0 %
Gilead Sciences Inc Q2 2026+10.2 %+12.1 %--
Pfizer IncQ2 2026+2.6 %+4.0 %--
Vertex Pharmaceuticals IncQ2 2026+12.5 %+11.6 %+6.5 %+6.6 %
PEERS TOTAL+16.0 %+10.4 %-53.0 %-54.3 %
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Sagimet Biosciences Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Sagimet Biosciences inc Q2 2026----
Eli Lilly And CompanyQ2 2026+33.5 %-8.6 %+72.8 %+26.1 %
Novartis AgQ4 2025+18.3 %+18.3 %+13.3 %+13.3 %
Gilead Sciences Inc Q2 2026+5.2 %+9.3 %+30.8 %+19.7 %
Pfizer IncQ2 2026+8.3 %+15.3 %-13.8 %+22.2 %
Vertex Pharmaceuticals IncQ2 2026+20.0 %+24.5 %-23.0 %-15.9 %
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Sagimet Biosciences Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Sagimet Biosciences inc -----
Eli Lilly And Company21.97%33.95%92.54%4.400.92
Novartis Ag12.59%12.62%30.00%6.34-
Gilead Sciences Inc ---6.153.35
Pfizer Inc2.12%2.53%4.91%4.981.60
Vertex Pharmaceuticals Inc16.88%19.97%23.31%6.191.03
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Sagimet Biosciences Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Sagimet Biosciences inc ---753.152.06
Eli Lilly And Company39.7713.290.28189.9431.25
Novartis Ag20.535.0727.5625.066.17
Gilead Sciences Inc -6.21--15.99
Pfizer Inc37.662.57--1.91
Vertex Pharmaceuticals Inc30.7710.70-114.896.65
PEERS AVERAGE49.037.72111.278.39
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.