Lixte Biotechnology Holdings Inc's Competitiveness
A competitive positioning analysis and financial ratio benchmarking of Lixte Biotechnology Holdings Inc (LIXT) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.
Lixte Biotechnology Holdings Inc's Competitor Quality Breadth
Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).
| Entity | Profitable | Expanding | Above Industry Growth | Distressed |
|---|---|---|---|---|
| Lixte Biotechnology Holdings Inc | - | - | - | No |
| Competitors combined (51) |
Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.
LIXT Stock Performance relative to its Competitors
5 Best-Performing Tracked Competitors, Trailing 12 Months
| # | Competitor | TTM Share Price Return | vs U.S.A. 500 |
|---|---|---|---|
| 1 | Adlai Nortye Ltd | 282.9% | Outperformed |
| 2 | Erasca Inc | 282.9% | Outperformed |
| 3 | Nurix Therapeutics Inc | 282.9% | Outperformed |
| 4 | Enliven Therapeutics Inc | 282.9% | Outperformed |
| 5 | Palvella Therapeutics Inc | 282.9% | Outperformed |
TTM share price return and U.S.A. 500 outperformance for Lixte Biotechnology Holdings Inc's best-performing tracked competitors requires a Commercial License.
Source: CSIMarket API, trailing 12 months.
Lixte Biotechnology Holdings Inc's Comment on Competition and Industry Peers
Publicly Traded Peers of Lixte Biotechnology Holdings Inc
Revenue and income for trailing 12 months, in millions of $, except employees| Company | Market Cap | Revenues |
|---|---|---|
| Lixte Biotechnology Holdings Inc | 54.57 | - |
| Madrigal Pharmaceuticals Inc | 14,688.05 | 1,283.94 |
| Nuvalent Inc | 9,751.98 | 4.23 |
| Blueprint Medicines Corporation | 8,615.12 | 562.12 |
| Rhythm Pharmaceuticals Inc | 6,531.05 | 239.92 |
| Terns Pharmaceuticals Inc | 4,933.17 | - |
| SUBTOTAL | 70,781.32 | 3,889.60 |
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Sources: Lixte Biotechnology Holdings Inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Lixte Biotechnology Holdings Inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.
Lixte Biotechnology Holdings Inc's Business Segment Mix vs Peers
Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).| Company | Largest Segment |
|---|---|
| Madrigal Pharmaceuticals Inc | Reportable 100.00 % |
| Blueprint Medicines Corporation | Single Reportable Segment 100.00 % |
| Rhythm Pharmaceuticals Inc | Single Reportable 100.00 % |
| Supernus Pharmaceuticals inc | Reportable 100.00 % |
| Rigel Pharmaceuticals Inc | One Operating 100.00 % |
Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).
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Lixte Biotechnology Holdings Inc's Productivity vs Peers Comparison
Revenue and income per employee, trailing 12 months, in $; market cap in millions of $| Company | Market Cap | Revenue / Employee | Income / Employee |
|---|---|---|---|
| Lixte Biotechnology Holdings Inc | 55 | - | -2,952,080 |
| Madrigal Pharmaceuticals Inc | 14,688 | 1,403,213 | -355,295 |
| Nuvalent Inc | 9,752 | 18,566 | -1,974,009 |
| Blueprint Medicines Corporation | 8,615 | 965,844 | -267,576 |
| Rhythm Pharmaceuticals Inc | 6,531 | 579,512 | -507,783 |
| Terns Pharmaceuticals Inc | 4,933 | - | -1,630,627 |
| PEERS TOTAL | 70,727 | 677,630 | -631,685 |
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Lixte Biotechnology Holdings Inc's Geographic Revenue Exposure vs Peers
Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.| Company | Largest Market |
|---|---|
| Xoma Royalty Corporation | CH 54.36 % |
| Adc Therapeutics Sa | United States 96.08 % |
| Integrated Biopharma Inc | US 83.83 % |
Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.
Lixte Biotechnology Holdings Inc's Position in Industry Market Structure
Market-capitalization share and concentration across all 498 companies in Lixte Biotechnology Holdings Inc's industry classification, broader than the peer set above. Market cap in millions of $.Lixte Biotechnology Holdings Inc ranks #0 of 498 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 827, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).
| Rank | Company | Market Cap | Industry Share |
|---|---|---|---|
| 1 | Eli Lilly And Company | 1,060,478 | 19.39 % |
| 2 | Johnson and Johnson | 652,141 | 11.92 % |
| 3 | Beone Medicines Ltd | 560,341 | 10.24 % |
| 4 | Abbvie Inc | 468,722 | 8.57 % |
| 5 | Merck and Co Inc | 1,234 | 5.2% |
| 6 | Novartis Ag | 1,234 | 5.2% |
| 7 | Abbott Laboratories | 1,234 | 5.2% |
| 8 | Novo Nordisk A | 1,234 | 5.2% |
| 9 | Pfizer Inc | 1,234 | 5.2% |
| 10 | Vertex Pharmaceuticals Inc | 1,234 | 5.2% |
| 0 | Lixte Biotechnology Holdings Inc | 49 | 0.00 % |
Market cap and industry share for the rest of Lixte Biotechnology Holdings Inc's industry peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-03.
Lixte Biotechnology Holdings Inc's Valuation vs Competitive Position
Valuation multiples vs the Major Pharmaceutical Preparations industry average (341 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.| Metric | Company | Industry Average | Difference |
|---|---|---|---|
| P/E | - | 25.5x | - |
| EV / EBITDA | - | 17.3x | - |
| P/B | 6.4x | 4.5x | +1.8x |
| Return on Equity | -70.79 % | industry aggregate | -88.04 % |
| Return on Invested Capital | -30.41 % | -2.97 % (avg) | -27.44 % |
Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.
Lixte Biotechnology Holdings Inc's Multi-Year Financial Trajectory
Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.| Metric | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|
| Revenue Growth | - | - | - | - | - | - | - | - |
| Operating Margin | - | - | - | - | - | - | - | - |
| Return on Invested Capital | -86.00 % | -40.50 % | -66.11 % | -52.96 % | -56.00 % | -64.88 % | -94.44 % | -55.06 % |
| P/E | - | - | - | - | - | - | - | - |
Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.
Lixte Biotechnology Holdings Inc's Competitive Forces (Porter's Five Forces)
Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.| Force | Assessment | Basis |
|---|---|---|
| Competitive Rivalry | High | Industry HHI of 827 (see Industry Market Structure & Concentration above) |
| Supplier Power | Not covered on this page | See Lixte Biotechnology Holdings Inc's dedicated suppliers page for concentration and dependency data |
| Buyer Power | Not covered on this page | See Lixte Biotechnology Holdings Inc's dedicated customers page for concentration and dependency data |
| Threat of Substitutes | - | No systematic data source for cross-product substitution exists in this system; not estimated |
Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.
Lixte Biotechnology Holdings Inc's SWOT
Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.Strengths
No rule matched.
Weaknesses
- Return on equity 88.0 points below the industry aggregate.
Opportunities
- A meaningful share of tracked competitors (44.00 %) show financial-distress signals, a possible opening to gain share.
Threats
No rule matched.
Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.
Lixte Biotechnology Holdings Inc's Financial Strength vs Peers Comparison
Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months| Company | Quick Ratio | Working Capital | Debt / Equity |
|---|---|---|---|
| Lixte Biotechnology Holdings Inc | 5.22 | 7.28 | - |
| Madrigal Pharmaceuticals Inc | 0.72 | 3.52 | 0.60 |
| Nuvalent Inc | 1.98 | 13.90 | - |
| Blueprint Medicines Corporation | 0.36 | 3.16 | 2.48 |
| Rhythm Pharmaceuticals Inc | 1.14 | 4.16 | 0.84 |
| Terns Pharmaceuticals Inc | 17.26 | 35.60 | - |
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.
Lixte Biotechnology Holdings Inc's Revenue and Income Growth vs Peers
Quarterly revenue and net income growth, year over year and quarter over quarter| Company | Period | Revenue Y/Y | Income Y/Y |
|---|---|---|---|
| Lixte Biotechnology Holdings Inc | Q2 2026 | - | - |
| Madrigal Pharmaceuticals Inc | Q2 2026 | +71.2 % | - |
| Nuvalent Inc | Q1 2026 | - | - |
| Blueprint Medicines Corporation | Q1 2025 | +55.5 % | -99.4 % |
| Rhythm Pharmaceuticals Inc | Q2 2026 | +46.9 % | - |
| Terns Pharmaceuticals Inc | Q4 2025 | - | - |
| PEERS TOTAL | +26.3 % | - |
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.
Lixte Biotechnology Holdings Inc's Peers' Costs of Sales and Capital Expenditures
Context for revenue growth: peer costs and capex, year over year and quarter over quarter| Company | Period | Costs Y/Y | Capex Y/Y |
|---|---|---|---|
| Lixte Biotechnology Holdings Inc | Q2 2026 | - | - |
| Madrigal Pharmaceuticals Inc | Q2 2026 | - | - |
| Nuvalent Inc | Q1 2026 | - | - |
| Blueprint Medicines Corporation | Q1 2025 | -12.2 % | +65.9 % |
| Rhythm Pharmaceuticals Inc | Q2 2026 | +61.1 % | - |
| Terns Pharmaceuticals Inc | Q4 2025 | - | - |
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Lixte Biotechnology Holdings Inc's Returns and Turnover vs Peers
ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover| Company | ROA | ROI | ROE |
|---|---|---|---|
| Lixte Biotechnology Holdings Inc | - | - | - |
| Madrigal Pharmaceuticals Inc | - | - | - |
| Nuvalent Inc | - | - | - |
| Blueprint Medicines Corporation | - | - | - |
| Rhythm Pharmaceuticals Inc | - | - | - |
| Terns Pharmaceuticals Inc | - | - | - |
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).
Lixte Biotechnology Holdings Inc's Valuation vs Peers
P/E, price to sales, PEG, price to cash flow and price to book| Company | P/E | Price / Sales |
|---|---|---|
| Lixte Biotechnology Holdings Inc | - | - |
| Madrigal Pharmaceuticals Inc | - | 11.44 |
| Nuvalent Inc | - | 2,303.80 |
| Blueprint Medicines Corporation | - | 15.33 |
| Rhythm Pharmaceuticals Inc | - | 27.22 |
| Terns Pharmaceuticals Inc | - | - |
| PEERS AVERAGE | - | 18.20 |
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.