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Edgewise Therapeutics Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Edgewise Therapeutics Inc (EWTX) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q2 2026
Competitors Tracked
28
Publicly traded peers
Peer Group Market Share
-
Share of combined sales, Q2 2026
Revenue Growth Y/Y
-
Peers: 7.88 %
Net Margin
-
Peers: 23.28 %

Key Findings: Edgewise Therapeutics Inc vs Its Competitors

  • Scale: Edgewise Therapeutics Inc ranks #67 of 544 companies by market capitalization in the Major Pharmaceutical Preparations industry, holding 0.1% of industry market cap.

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/EWTX/competitors
https://api.csimarket.com/api/v1/companies/EWTX/relationships
https://api.csimarket.com/api/v1/companies/EWTX/similar
Programmatic access for models, analytics, and integration workflows.

Edgewise Therapeutics Inc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Edgewise Therapeutics inc - - - Yes
Competitors combined (28) 61% 81% 63% 32%
High-Confidence Competitors (7) 50% 33% 17% 17%
Similar-Size Competitors (10) 40% 60% 60% 44%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

EWTX Stock Performance relative to its Competitors

EWTX Competitors (weighted) Percent change over the selected range

Edgewise Therapeutics Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
55.6%beat U.S.A. 500
Competitors Combined
(15 of 27)
100%beat U.S.A. 500
High-Confidence
(5 of 5)
88.9%beat U.S.A. 500
Similar-Size
(8 of 9)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Edgewise Therapeutics inc 159.70 % Outperformed
Competitors combined (27) 40.4% 63.2%
High-Confidence Competitors (5) 40.4% 63.2%
Similar-Size Competitors (9) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Edgewise Therapeutics Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

EWTX Stock Performance relative to High-Confidence Competitors

EWTX High-Confidence Competitors (equal-weighted, 8) Percent change over the selected range

EWTX Stock Performance relative to Similar-Size Competitors

EWTX Similar-Size Competitors (equal-weighted, 10) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Verona Pharma Plc 282.9% Outperformed
2 Centessa Pharmaceuticals Plc 282.9% Outperformed
3 Apellis Pharmaceuticals Inc 282.9% Outperformed
4 Boundless Bio Inc 282.9% Outperformed
5 Kalvista Pharmaceuticals Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Edgewise Therapeutics Inc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Edgewise Therapeutics Inc's Comment on Competition and Industry Peers

The competitive landscape for emerging treatments for hypertrophic cardiomyopathy (HCM) includes several companies developing cardiac myosin inhibitors (CMIs). Bristol-Myers Squibb markets Camzyos (mavacamten), which is approved in the US, Europe, and other countries. Cytokinetics has received FDA approval and a positive opinion from the EMA for aficamten. Other companies involved in developing therapies targeting symptomatic obstructive HCM (oHCM) in patients with NYHA class II-III include Imbria Pharmaceuticals, Lexicon Pharmaceuticals, Celltrion, and Braveheart Bio. The company utilizes trade secrets, patents, and proprietary information to maintain its competitive position but acknowledges risks related to protecting such information. Additionally, pharmaceutical products may face competition from lower-priced products in foreign countries with price controls and imported foreign products, as well as challenges related to reimbursement and healthcare reform.

Publicly Traded Peers of Edgewise Therapeutics inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Edgewise Therapeutics inc 4,219.58 - -197.22 146
Johnson and Johnson 652,897.56 97,929.00 21,037.00 140,800
Vertex Pharmaceuticals Inc 134,421.50 12,587.20 4,405.20 405
Bristol myers Squibb Company 128,737.28 49,186.00 9,274.00 32,500
Regeneron Pharmaceuticals Inc 79,554.06 15,534.70 4,328.70 15,410
Alnylam Pharmaceuticals Inc 35,133.05 4,804.18 807.99 2,500
SUBTOTAL 1,117,255.43 196,596.30 39,749.55 200,575
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Sources: Edgewise Therapeutics inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Edgewise Therapeutics inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Edgewise Therapeutics Inc's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
LianBio Named by the company 85% 2022 to 2026 3
Cytokinetics Incorporated Named by the company 85% 2022 to 2026 3
Imbria Pharmaceuticals Named by the company 85% 2022 to 2026 3
Bristol-Myers Squibb Named by the company 85% 2022 to 2026 3
Pfizer Named by the company 85% 2022 to 2026 3
BMS Named by the company 85% 2022 to 2026 3
Lexicon Pharmaceuticals Named by the company 85% 2022 to 2026 3
Bridgebio Pharma Inc Named by the company 85% 2022 to 2026 3
Celltrion Named by the company 85% 2022 to 2026 3
Braveheart Bio Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for Edgewise Therapeutics Inc's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

Edgewise Therapeutics Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Johnson and Johnson Oncology 29.26 % Immunology 15.19 % Surgery 10.48 %
Vertex Pharmaceuticals Inc Pharmaceuticals 100.00 % - -
Centessa Pharmaceuticals Plc Reportable 100.00 % - -
Apellis Pharmaceuticals Inc Reportable Segment Aggregation Before Other Operating Segment 100.00 % - -
Sarepta Therapeutics Inc All Other Segments 100.00 % - -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Edgewise Therapeutics Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Edgewise Therapeutics inc 4,220 - -1,350,836
Johnson and Johnson 652,898 695,518 149,411
Vertex Pharmaceuticals Inc 134,421 31,079,506 10,877,037
Bristol myers Squibb Company 128,737 1,513,415 285,354
Regeneron Pharmaceuticals Inc 79,554 1,008,092 280,902
Alnylam Pharmaceuticals Inc 35,133 1,921,673 323,195
PEERS TOTAL 1,113,036 980,878 199,306
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Edgewise Therapeutics Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Johnson and Johnson United States 57.42 % Europe 22.62 % Asia-Pacific, Africa 14.78 %
Vertex Pharmaceuticals Inc United States 61.68 % Europe 29.33 % Other Countries Outside of the United States and Europe 8.99 %
Bristol myers Squibb Company United States 67.79 % Non-US 29.98 % Other Region 2.24 %
United Therapeutics Corporation UNITED STATES 95.23 % Non-US 4.77 % -
Nuvation Bio Inc US 92.98 % CN 6.23 % JP 0.78 %

Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

Edgewise Therapeutics Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 498 companies in Edgewise Therapeutics Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Edgewise Therapeutics Inc ranks #67 of 498 companies by market capitalization in its industry, holding 0.08 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 824, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Eli Lilly And Company 1,054,271 19.27 %
2 Johnson and Johnson 662,243 12.10 %
3 Beone Medicines Ltd 543,752 9.94 %
4 Abbvie Inc 473,291 8.65 %
5 Merck and Co Inc 1,234 5.2%
6 Novartis Ag 1,234 5.2%
7 Abbott Laboratories 1,234 5.2%
8 Novo Nordisk A 1,234 5.2%
9 Pfizer Inc 1,234 5.2%
10 Vertex Pharmaceuticals Inc 1,234 5.2%
67 Edgewise Therapeutics inc 4,222 0.08 %
Full Industry Market Structure

Market cap and industry share for the rest of Edgewise Therapeutics Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-29.

Edgewise Therapeutics Inc's Same-Size Peers & Stock Performance

Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.
Rank Company Market Cap TTM Return 3M Momentum Beta Sharpe (1Y)
62 Dianthus Therapeutics Inc 4,833 128.44 % -9.85 % 1.11 1.48
63 Veradermics Inc 4,576 - -7.29 % - 2.21
64 Indivior Pharmaceuticals Inc 4,525 52.55 % -8.75 % 0.79 1.17
65 Abcellera Biologics Inc 4,446 206.96 % 84.88 % 1.70 1.69
66 Erasca Inc 1,234 12.3% 4.5% 1.10 0.80
67 Edgewise Therapeutics inc 4,222 159.67 % -4.18 % 1.48 1.30
68 Viking Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
69 Telix Pharmaceuticals Ltd 1,234 12.3% 4.5% 1.10 0.80
70 Organon and Co 1,234 12.3% 4.5% 1.10 0.80
71 Arcutis Biotherapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
72 Tango Therapeutics Inc 1,234 12.3% 4.5% 1.10 0.80
Full Same-Size Peer Performance

Market cap, return, momentum, beta and Sharpe ratio for the rest of Edgewise Therapeutics Inc's same-size peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-09-29. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.

Edgewise Therapeutics Inc's Valuation vs Competitive Position

Valuation multiples vs the Major Pharmaceutical Preparations industry average (341 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 25.1x -
EV / EBITDA - 17.3x -
P/B 7.9x 4.5x +3.4x
Return on Equity -39.01 % industry aggregate -56.26 %
Return on Invested Capital -21.59 % -2.95 % (avg) -18.64 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Edgewise Therapeutics Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 20212022202320242025
Revenue Growth -----
Operating Margin -----
Return on Invested Capital -3.06 %-18.17 %-15.87 %-18.18 %
P/E -----

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Edgewise Therapeutics Inc's BCG Growth-Share Matrix

Relative market share (vs Edgewise Therapeutics Inc's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.

Question Mark Star Dog Cash Cow Relative Market Share (vs largest competitor) Industry Revenue Growth (%) Edgewise Therapeutics Inc

Edgewise Therapeutics Inc falls in the Dog quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 8.0% (median, trailing 12 months).

Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.

Edgewise Therapeutics Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 824 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Edgewise Therapeutics Inc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Edgewise Therapeutics Inc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Edgewise Therapeutics Inc's Industry Attractiveness & Competitive Strength

A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.

High Strength
Medium Strength
Low Strength
High Attractiveness
Invest / Grow
Invest / Grow
Selective
Medium Attractiveness
Invest / Grow
Selective
Harvest
Low Attractiveness
Selective
Harvest
Harvest / Divest Edgewise Therapeutics Inc

Edgewise Therapeutics Inc falls in the Low attractiveness / Low strength cell: Harvest / Divest.

Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.

Edgewise Therapeutics Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

  • Outperforming the U.S.A. 500 over the trailing 12 months.

Weaknesses

  • Return on equity 56.3 points below the industry aggregate.
  • Low relative market share vs the industry leader (0.00x).
  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

  • A meaningful share of tracked competitors (32.00 %) show financial-distress signals, a possible opening to gain share.

Threats

No rule matched.

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Edgewise Therapeutics Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Edgewise Therapeutics inc 2.11 20.86 - -
Johnson and Johnson 0.37 1.05 0.60 0.49
Vertex Pharmaceuticals Inc 1.34 2.85 - 0.48
Bristol myers Squibb Company 0.49 1.35 2.31 0.54
Regeneron Pharmaceuticals Inc 0.57 3.74 0.06 0.38
Alnylam Pharmaceuticals Inc 1.12 2.86 1.18 0.94
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Edgewise Therapeutics Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Edgewise Therapeutics inc Q2 2026----
Johnson and JohnsonQ2 2026+6.6 %+5.2 %-0.1 %+5.7 %
Vertex Pharmaceuticals IncQ2 2026+12.5 %+11.6 %+6.5 %+6.6 %
Bristol myers Squibb CompanyQ2 2026+5.7 %+12.9 %+152.6 %+23.8 %
Regeneron Pharmaceuticals Inc Q2 2026+16.7 %+19.0 %-6.8 %+78.3 %
Alnylam Pharmaceuticals Inc Q2 2026+66.9 %+10.6 %--20.1 %
PEERS TOTAL+7.9 %+7.7 %+27.7 %+15.1 %
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Edgewise Therapeutics Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Edgewise Therapeutics inc Q2 2026----87.7 %
Johnson and JohnsonQ2 2026+5.5 %-0.7 %+26.7 %+25.9 %
Vertex Pharmaceuticals IncQ2 2026+20.0 %+24.5 %-23.0 %-15.9 %
Bristol myers Squibb CompanyQ2 2026+10.5 %+8.9 %-15.5 %-12.1 %
Regeneron Pharmaceuticals Inc Q2 2026+109.2 %+54.4 %+9.7 %+4.2 %
Alnylam Pharmaceuticals Inc Q2 2026+110.0 %+43.7 %+142.6 %+58.8 %
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Edgewise Therapeutics Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Edgewise Therapeutics inc -----
Johnson and Johnson10.60%13.30%25.74%5.472.17
Vertex Pharmaceuticals Inc16.88%19.97%23.31%6.191.03
Bristol myers Squibb Company10.27%13.58%46.65%4.605.37
Regeneron Pharmaceuticals Inc 10.60%11.83%13.81%2.620.49
Alnylam Pharmaceuticals Inc 15.76%22.10%93.61%5.4311.45
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Edgewise Therapeutics Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Edgewise Therapeutics inc ---145.939.42
Johnson and Johnson30.976.67-353.877.68
Vertex Pharmaceuticals Inc30.7110.68-114.686.64
Bristol myers Squibb Company13.842.620.20-5.77
Regeneron Pharmaceuticals Inc 18.595.126.12176.632.51
Alnylam Pharmaceuticals Inc 44.977.31-59.1825.95
PEERS AVERAGE28.115.68654.626.19
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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