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Essa Pharma Inc's Competitiveness

A competitive positioning analysis and financial ratio benchmarking of Essa Pharma Inc (EPIX) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.

Peer Data As of Q3 2025
Competitors Tracked
65
Publicly traded peers
Peer Group Market Share
-
Share of combined sales, Q3 2025
Revenue Growth Y/Y
-
Peers: 32.45 %
Net Margin
-
Peers: -90.00 %

Key Findings: Essa Pharma Inc vs Its Competitors

  • TTM: Trailing 12-month revenue of 1M vs 5,220M combined for tracked competitors (0.0% combined share).
  • Peer differentiation: Revenue per employee of $0.03M compares with $0.64M for the peer group (0.1x).

Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).

API endpoints for this dataset
https://api.csimarket.com/api/v1/companies/EPIX/competitors
https://api.csimarket.com/api/v1/companies/EPIX/relationships
https://api.csimarket.com/api/v1/companies/EPIX/similar
Programmatic access for models, analytics, and integration workflows.

Essa Pharma Inc vs. its Competitors, Q3 2025

TTM net margin

Essa Pharma Inc -4,205.6 %
Competitors combined -64.6 %

TTM = trailing twelve months. Run-rate annualizes the latest quarter (×4) and compares it to TTM. In millions of $. High-Confidence Competitors are named as a competitor directly in an SEC filing; Similar-Size Competitors are the closest peers by market-cap rank within the same industry; Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC, all independent of the competitor list.

Competitor Financial Benchmarking - TTM Commercial

TTM revenue, latest-quarter run-rate and net income/margin benchmarked across Essa Pharma Inc and its 4 competitor groupings. Available under Commercial License.

Entity TTM Revenue Latest Q ×4 Rev Run-rate vs TTM TTM Net Income TTM Net Margin
Essa Pharma inc $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitors combined $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
High-Confidence Competitors (6) $12,345M $12,345M +12.3% · Accelerating $1,234M 12.3%
Competitor Financial Benchmarking

TTM revenue, run-rate and net margin benchmarking across Essa Pharma Inc's competitor groups requires a Commercial License.

Essa Pharma Inc's Competitor Quality Breadth

Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).

Entity Profitable Expanding Above Industry Growth Distressed
Essa Pharma inc - - - Yes
Competitors combined (65) 24% 80% 60% 51%
High-Confidence Competitors (8) 88% 63% 38% 38%

Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.

EPIX Stock Performance relative to its Competitors

EPIX Competitors (weighted) Percent change over the selected range

Essa Pharma Inc's Share Price Performance vs Peer Groups

Trailing 12-month total share price return, and the share of each group that outperformed the U.S.A. 500 over the same period. Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC.
38.5%beat U.S.A. 500
Competitors Combined
(20 of 52)
71.4%beat U.S.A. 500
High-Confidence
(5 of 7)
Entity TTM Share Price Return
(group: median)
vs U.S.A. 500
Essa Pharma inc -96.90 % Underperformed
Competitors combined (52) 40.4% 63.2%
High-Confidence Competitors (7) 40.4% 63.2%
Similar-Size Competitors (0) 40.4% 63.2%
Similar Growth & Profitability (0) 40.4% 63.2%
Peer Group Share Price Returns

TTM share price return and U.S.A. 500 outperformance for Essa Pharma Inc's competitor groups requires a Commercial License.

Source: CSIMarket API (daily market-structure computation). Outperformance is trailing-12-month total return vs the U.S.A. 500 over the same window, not risk-adjusted.

EPIX Stock Performance relative to High-Confidence Competitors

EPIX High-Confidence Competitors (equal-weighted, 8) Percent change over the selected range

5 Best-Performing Tracked Competitors, Trailing 12 Months

#CompetitorTTM Share Price Returnvs U.S.A. 500
1 Adlai Nortye Ltd 282.9% Outperformed
2 Erasca Inc 282.9% Outperformed
3 Spyre Therapeutics Inc 282.9% Outperformed
4 Nurix Therapeutics Inc 282.9% Outperformed
5 Enliven Therapeutics Inc 282.9% Outperformed
Best-Performing Competitor Returns

TTM share price return and U.S.A. 500 outperformance for Essa Pharma Inc's best-performing tracked competitors requires a Commercial License.

Source: CSIMarket API, trailing 12 months.

Essa Pharma Inc's Comment on Competition and Industry Peers

The prostate cancer market is characterized by intense competition among companies with substantial financial resources and expertise in research, development, manufacturing, clinical trials, regulatory approvals, and marketing. Mergers and acquisitions have led to resource concentration among fewer competitors. Several pharmaceutical therapies are approved and available, with new molecules under investigation. Approved therapies and their manufacturers include Enzalutamide (Xtandi) by Astellas and Pfizer; Abiraterone acetate (Zytiga) by Johnson & Johnson; Abiraterone acetate (Yonsa) by Sun Pharma; Sipuleucel-T (Provenge) by Valeant; Docetaxel and Cabazitaxel by Sanofi; Olaparib/abiraterone acetate (Akeega) by Johnson & Johnson; and Talazaparib (Talzenna) by Pfizer. Generic versions of Zytiga are also approved and commercially available in the U.S. ESSA considers its competitive position strong due to its product candidate's unique mechanism targeting androgen receptor activation, which may circumvent resistance pathways associated with existing hormone-related therapies. Competitors identified include Astellas, Johnson & Johnson, Pfizer, Sanofi, Sun Pharma, and Valeant.

Publicly Traded Peers of Essa Pharma inc

Revenue and income for trailing 12 months, in millions of $, except employees
Company Market Cap Revenues Income Employees
Essa Pharma inc 8.93 0.60 -25.27 18
Zai Lab Limited 29,264.70 449.61 -188.21 1,784
Madrigal Pharmaceuticals Inc 14,771.11 1,283.94 -325.10 915
Protagonist Therapeutics inc 10,007.73 281.99 81.35 132
Nuvalent Inc 9,751.98 4.23 -450.07 228
Tg Therapeutics Inc 8,817.22 799.54 441.49 399
SUBTOTAL 121,979.16 6,068.99 -4,067.68 9,459
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Sources: Essa Pharma inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Essa Pharma inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.

Essa Pharma Inc's Competitors Named by the Company

Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.
Competitor Basis Confidence Active Sources
Novartis Named by the company 85% 2022 to 2026 3
Johnson & Johnson Named by the company 85% 2022 to 2026 3
Sun Pharma Named by the company 85% 2022 to 2026 3
Clovis Oncology Named by the company 85% 2022 to 2026 3
Pfizer Named by the company 85% 2022 to 2026 3
Astellas Named by the company 85% 2022 to 2026 3
Merck Named by the company 85% 2022 to 2026 3
Valeant Named by the company 85% 2022 to 2026 3
ESSA Named by the company 85% 2022 to 2026 3
Sanofi Named by the company 85% 2022 to 2026 3
AstraZeneca Named by the company 85% 2022 to 2026 3
Arvinas Inc Named by the company 85% 2022 to 2026 3
Madrigal Pharmaceuticals Inc Named by the company 85% 2022 to 2026 3
Intercept Pharmaceuticals inc Named by the company 85% 2022 to 2026 3
Competitor Evidence Detail

Filing basis, confidence, active dates and source counts for Essa Pharma Inc's named competitors require a Commercial License.

Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.

Essa Pharma Inc's Business Segment Mix vs Peers

Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).
Company Largest Segment 2nd Segment 3rd Segment
Madrigal Pharmaceuticals Inc Reportable 100.00 % - -
Protagonist Therapeutics inc Single reportable segment 100.00 % - -
Blueprint Medicines Corporation Single Reportable Segment 100.00 % - -
Rhythm Pharmaceuticals Inc Single Reportable 100.00 % - -
Supernus Pharmaceuticals inc Reportable 100.00 % - -

Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).

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Essa Pharma Inc's Productivity vs Peers Comparison

Revenue and income per employee, trailing 12 months, in $; market cap in millions of $
CompanyMarket CapRevenue / EmployeeIncome / Employee
Essa Pharma inc 9 33,375 -1,403,623
Zai Lab Limited 29,265 252,026 -105,501
Madrigal Pharmaceuticals Inc 14,771 1,403,213 -355,295
Protagonist Therapeutics inc 10,008 2,136,303 616,273
Nuvalent Inc 9,752 18,566 -1,974,009
Tg Therapeutics Inc 8,817 2,003,850 1,106,491
PEERS TOTAL 121,970 642,770 -428,177
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Essa Pharma Inc's Geographic Revenue Exposure vs Peers

Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.
Company Largest Market 2nd Market 3rd Market
Xoma Royalty Corporation CH 54.36 % US 45.64 % -
Adc Therapeutics Sa United States 96.08 % EMEA 3.92 % -

Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.

Essa Pharma Inc's Position in Industry Market Structure

Market-capitalization share and concentration across all 498 companies in Essa Pharma Inc's industry classification, broader than the peer set above. Market cap in millions of $.

Essa Pharma Inc ranks #0 of 498 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 827, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).

Rank Company Market Cap Industry Share
1 Eli Lilly And Company 1,060,478 19.39 %
2 Johnson and Johnson 652,141 11.92 %
3 Beone Medicines Ltd 560,341 10.24 %
4 Abbvie Inc 468,722 8.57 %
5 Merck and Co Inc 1,234 5.2%
6 Novartis Ag 1,234 5.2%
7 Abbott Laboratories 1,234 5.2%
8 Novo Nordisk A 1,234 5.2%
9 Pfizer Inc 1,234 5.2%
10 Vertex Pharmaceuticals Inc 1,234 5.2%
0 Essa Pharma inc 9 0.00 %
Full Industry Market Structure

Market cap and industry share for the rest of Essa Pharma Inc's industry peers requires a Commercial License.

Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2025-10-08.

Essa Pharma Inc's Valuation vs Competitive Position

Valuation multiples vs the Major Pharmaceutical Preparations industry average (342 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns. See the full Major Pharmaceutical Preparations industry valuation benchmarks.
Metric Company Industry Average Difference
P/E - 25.1x -
EV / EBITDA - 17.3x -
P/B 0.7x 4.5x -3.9x
Return on Equity -21.70 % industry aggregate -40.59 %
Return on Invested Capital 12.73 % -2.95 % (avg) 15.68 %

Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.

Essa Pharma Inc's Multi-Year Financial Trajectory

Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.
Metric 20202021202220232024
Revenue Growth -----
Operating Margin -15,040.21 %---
Return on Invested Capital -14.19 %3.12 %10.75 %14.43 %
P/E -----

Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.

Essa Pharma Inc's Competitive Forces (Porter's Five Forces)

Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.
Force Assessment Basis
Competitive Rivalry High Industry HHI of 827 (see Industry Market Structure & Concentration above)
Supplier Power Not covered on this page See Essa Pharma Inc's dedicated suppliers page for concentration and dependency data
Buyer Power Not covered on this page See Essa Pharma Inc's dedicated customers page for concentration and dependency data
Threat of Substitutes - No systematic data source for cross-product substitution exists in this system; not estimated

Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.

Essa Pharma Inc's SWOT

Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.

Strengths

No rule matched.

Weaknesses

  • Return on equity 40.6 points below the industry aggregate.
  • Underperforming the U.S.A. 500 over the trailing 12 months.
  • Piotroski F-Score of 2 or below, the standard financial-distress signal.

Opportunities

  • A meaningful share of tracked competitors (50.80 %) show financial-distress signals, a possible opening to gain share.

Threats

  • Tracked peer group's revenue run-rate is broadly decelerating (-21.9% annualized).

Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.

Essa Pharma Inc's Financial Strength vs Peers Comparison

Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months
CompanyQuick RatioWorking CapitalDebt / EquityAsset Turnover
Essa Pharma inc 35.84 46.14 - 0.01
Zai Lab Limited 1.66 2.45 0.31 0.40
Madrigal Pharmaceuticals Inc 0.72 3.52 0.60 1.01
Protagonist Therapeutics inc 5.28 15.94 - 0.38
Nuvalent Inc 1.98 13.90 - 0.00
Tg Therapeutics Inc 1.58 4.52 0.81 0.61
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.

Essa Pharma Inc's Revenue and Income Growth vs Peers

Quarterly revenue and net income growth, year over year and quarter over quarter
CompanyPeriodRevenue Y/YRevenue Q/QIncome Y/YIncome Q/Q
Essa Pharma inc Q2 2025----
Zai Lab LimitedQ2 2026-3.3 %+6.7 %--
Madrigal Pharmaceuticals Inc Q2 2026+71.2 %+17.0 %--
Protagonist Therapeutics inc Q2 2026+3,749.2 %+278.7 %-+4,204.8 %
Nuvalent Inc Q1 2026----
Tg Therapeutics Inc Q2 2026+70.3 %+17.3 %-72.4 %-60.7 %
PEERS TOTAL+55.2 %+49.1 %--
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.

Essa Pharma Inc's Peers' Costs of Sales and Capital Expenditures

Context for revenue growth: peer costs and capex, year over year and quarter over quarter
CompanyPeriodCosts Y/YCosts Q/QCapex Y/YCapex Q/Q
Essa Pharma inc Q2 2025----
Zai Lab LimitedQ2 2026+12.0 %+25.7 %-53.5 %-87.4 %
Madrigal Pharmaceuticals Inc Q2 2026---+10.5 %
Protagonist Therapeutics inc Q2 2026---79.3 %-21.9 %
Nuvalent Inc Q1 2026----
Tg Therapeutics Inc Q2 2026+117.5 %+22.9 %+597.6 %+474.5 %
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Essa Pharma Inc's Returns and Turnover vs Peers

ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover
CompanyROAROIROEReceivables TurnoverInventory Turnover
Essa Pharma inc ---1.91-
Zai Lab Limited---5.713.39
Madrigal Pharmaceuticals Inc ---8.190.12
Protagonist Therapeutics inc 11.02%11.66%11.80%--
Nuvalent Inc -----
Tg Therapeutics Inc 33.59%39.26%72.30%2.341.03
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).

Essa Pharma Inc's Valuation vs Peers

P/E, price to sales, PEG, price to cash flow and price to book
CompanyP/EPrice / SalesPEGP/CFPrice / Book
Essa Pharma inc -14.87--0.08
Zai Lab Limited-65.09--48.21
Madrigal Pharmaceuticals Inc -11.50-145.2628.20
Protagonist Therapeutics inc 138.1835.49-39.7911.89
Nuvalent Inc -2,303.80-250.718.30
Tg Therapeutics Inc 20.4311.030.0224.9414.60
PEERS AVERAGE-20.10122.948.78
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.

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