Kiniksa Pharmaceuticals International Plc (KNSA) Quarterly and Annual Segment Results by Country and Region - CSIMarket
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Kiniksa Pharmaceuticals International Plc  (NASDAQ: KNSA)

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Description of Kiniksa Pharmaceuticals International Plc's Business Segments


Kiniksa Pharmaceuticals International Plc is a biopharmaceutical company that is dedicated to advancing therapies in the fields of immunology and inflammation. The company has developed a robust portfolio organized into various segments, each targeting distinct therapeutic areas. Below is a comprehensive overview of the segments, products, and services offered by Kiniksa Pharmaceuticals.

Segments:

1. Rare Disease:
Kiniksa Pharmaceuticals has made significant strides in the rare disease segment, focusing on conditions that often lack effective treatments due to their low prevalence. The company aims to leverage innovative therapeutic approaches to address unmet needs in this area. One of the key products in this segment is KPL-716, a promising investigational therapeutic aimed at treating immune thrombocytopenia. This condition involves a low platelet count and is often linked to autoimmune responses, making targeted treatment crucial for patients.

2. Autoimmune Disease:
Within the autoimmune disease segment, Kiniksa Pharmaceuticals is committed to developing and commercializing novel therapies. This segment addresses a wide range of autoimmune conditions, which can significantly impact patients quality of life. KPL-716 plays a dual role here, as it is also being evaluated for use in other autoimmune diseases such as lupus and rheumatoid arthritis. This highlights the drugs versatility and the companys dedication to finding effective solutions for multiple patient populations.

3. Neurological Disease:
The neurological disease segment seeks to address complex neurodegenerative disorders that affect millions of individuals worldwide. KPL-404, a kinase inhibitor, is a central figure in this endeavor, specifically targeting huntingtons disease—a progressive and debilitating disorder. The development of KPL-404 reflects Kiniksas focus on innovative therapies that can significantly alter the course of neurological diseases and improve patient outcomes.

Products:

1. KPL-404:
KPL-404 represents a cutting-edge approach in the treatment of neurodegenerative conditions. By inhibiting specific kinases that play a role in disease progression, KPL-404 aims to halt or slow down the progression of Huntingtons disease and potentially other related neurological disorders.

2. KPL-716:
As one of the flagship products, KPL-716 is a monoclonal antibody tailored for the treatment of autoimmune disorders. Its dual evaluation for immune thrombocytopenia and various autoimmune diseases reflects Kiniksas strategic vision of leveraging single product candidates to address different indications, thereby maximizing therapeutic innovations.

3. KPL-914:
Another notable product from Kiniksa is KPL-914, a nano-antibody designed to treat atopic dermatitis and associated allergic conditions. This platform technology stands to offer patients a less invasive and more effective treatment option, highlighting the companys focus on building a diverse portfolio that caters to multiple aspects of immune-related conditions.

Services:

1. Clinical Trials:
Kiniksa Pharmaceuticals actively engages in clinical trials as a core service to validate the efficacy and safety of its product candidates. The company has a dedicated team of researchers and experts responsible for designing trials, executing protocols, and analyzing data. This rigorous process ensures that Kiniksas therapies stand up to scientific scrutiny and regulatory standards.

2. Patient Support Programs:
Beyond product development, Kiniksa Pharmaceuticals emphasizes patient-centric care through robust support programs. These programs provide patients with critical resources, including education on their conditions, financial assistance options, and emotional support mechanisms. By fostering a supportive environment, Kiniksa reinforces its commitment to improving the overall patient experience, complimenting its therapeutic offerings.

3. Medical Education:
Kiniksa Pharmaceuticals is also invested in educating healthcare professionals about its products, therapeutic areas, and emerging research findings. Through a combination of online learning modules, live educational events, and informative resources, the company seeks to enhance the knowledge base of medical professionals, empowering them to make informed decisions about patient care.

In summary, Kiniksa Pharmaceuticals International Plc is actively engaged in a range of therapeutic areas with an emphasis on rare diseases, autoimmune conditions, and neurological disorders. The development and commercialization of innovative products like KPL-404, KPL-716, and KPL-914 demonstrate the companys commitment to advancing healthcare solutions, while its dedicated services support the needs of patients and healthcare providers alike.


Composition of Kiniksa Pharmaceuticals International Plc Revenues by Segments

 
Product revenue net    100 % of total Revenue
Accounts receivable    -0.62 % of total Revenue
Other current liabilities    9.03 % of total Revenue
Pharmaceutical    100 % of total Revenue
Pharmaceutical United States    99.91 % of total Revenue
Product    213.69 % of total Revenue
Pharmaceutical Segment    113.69 % of total Revenue
US    213.37 % of total Revenue
GB    0.32 % of total Revenue

Q1 three months ended (Mar 31 2026)
Revenues by Business Segments Revenues
(in millions $)
%
(of total Revenues)
Product revenue net 214.27 100 %
Accounts receivable -1.34 -0.62 %
Other current liabilities 19.35 9.03 %
Pharmaceutical 214.27 100 %
Pharmaceutical United States 214.07 99.91 %
Total 214.27 100 %
Product 457.87 213.69 %
Pharmaceutical Segment 243.60 113.69 %
US 457.18 213.37 %
GB 0.68 0.32 %




Q1 three months ended (Mar 31 2026)
Revenue Growth rates by Segment Y/Y Revenue
%
Q/Q Revenue
%
Product revenue net 55.51 % -
Accounts receivable - -
Other current liabilities -5.15 % -
Pharmaceutical 55.51 % -
Pharmaceutical United States 55.58 % -
Total 55.51 % -68.38 %
Product - -
Pharmaceutical Segment - -
US - -
GB - -




Q1 three months ended (Mar 31 2026)
Income by Business Segments Income
(in millions $)
%
(Profit Margin)
Total 22.59 10.54 %




Q1 three months ended (Mar 31 2026)
Income Growth rates by Segment Y/Y Income
%
Q/Q Income
%
Total 164.57 % -61.71 %




Annual Report on Kiniksa Pharmaceuticals International Plc Divisions, Sales by Country

 
Product revenue net   Product revenue net Segment contribution to total sales 100 % of total Revenue
Accounts receivable   Accounts receivable Segment contribution to total sales -0.12 % of total Revenue
Other current liabilities   Other current liabilities Segment contribution to total sales 3.01 % of total Revenue
Pharmaceutical   Pharmaceutical Segment contribution to total sales 100 % of total Revenue
Pharmaceutical United States   Pharmaceutical United States Segment contribution to total sales 99.88 % of total Revenue
Pharmaceutical United Kingdom   Pharmaceutical United Kingdom Segment contribution to total sales 0.12 % of total Revenue


Twelve months ended 2025
KNSA s Annual Revenue by Geography and Business Segments Sales
(in millions $)
%
(of total Sales)
Product revenue net 677.56 100 %
Accounts receivable -0.83 -0.12 %
Other current liabilities 20.40 3.01 %
Pharmaceutical 677.56 100 %
Pharmaceutical United States 676.75 99.88 %
Pharmaceutical United Kingdom 0.81 0.12 %
Total 677.56 100 %


Twelve months ended 2025
KNSA s Annual Income by Country and Business Segments Income
(in millions $)
%
(Profit Margin)
Total 59.01 8.71 %

Twelve months ended 2025
Annual Revenue and Income Growth by Country and Business Segments % Y/Y Sales Growth % Y/Y Income Growth
Product revenue net 62.47 % -
Accounts receivable - -
Other current liabilities 37.14 % -
Pharmaceutical 60.09 % -
Pharmaceutical United States 60.58 % -
Pharmaceutical United Kingdom -12.47 % -
Total 60.09 % -
License and collaboration revenue - -
Pharmaceutical Rest of world - -



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