Sqz Biotechnologies's Competitiveness
A competitive positioning analysis and financial ratio benchmarking of Sqz Biotechnologies (SQZB) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.
Key Findings: Sqz Biotechnologies vs Its Competitors
- TTM: Trailing 12-month revenue of 21M vs 8,884M combined for tracked competitors (0.2% combined share).
- Scale: Sqz Biotechnologies ranks #154 of 165 companies by market capitalization in the Biotechnology & Pharmaceuticals industry, holding 0.0% of industry market cap.
- Peer differentiation: Revenue per employee of $0.49M compares with $0.38M for the peer group (1.3x).
Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).
Sqz Biotechnologies vs. its Competitors, Q3 2023
TTM net margin
TTM = trailing twelve months. Run-rate annualizes the latest quarter (×4) and compares it to TTM. In millions of $. High-Confidence Competitors are named as a competitor directly in an SEC filing; Similar-Size Competitors are the closest peers by market-cap rank within the same industry; Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC, all independent of the competitor list.
TTM revenue, latest-quarter run-rate and net income/margin benchmarked across Sqz Biotechnologies and its 4 competitor groupings. Available under Commercial License.
| Entity | TTM Revenue | Rev Run-rate vs TTM |
|---|---|---|
| Sqz Biotechnologies Company | $12,345M | +12.3% · Accelerating |
| Competitors combined | $12,345M | +12.3% · Accelerating |
| Similar-Size Competitors (10) | $12,345M | +12.3% · Accelerating |
TTM revenue, run-rate and net margin benchmarking across Sqz Biotechnologies's competitor groups requires a Commercial License.
Sqz Biotechnologies's Competitor Quality Breadth
Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).
| Entity | Profitable | Expanding | Above Industry Growth | Distressed |
|---|---|---|---|---|
| Sqz Biotechnologies Company | - | - | - | Yes |
| Competitors combined (61) | ||||
| Similar-Size Competitors (10) |
Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.
SQZB Stock Performance relative to its Competitors
SQZB Stock Performance relative to Similar-Size Competitors
5 Best-Performing Tracked Competitors, Trailing 12 Months
| # | Competitor | TTM Share Price Return | vs U.S.A. 500 |
|---|---|---|---|
| 1 | Moderna Inc | 282.9% | Outperformed |
| 2 | Relay Therapeutics Inc | 282.9% | Outperformed |
| 3 | Immunitybio inc | 282.9% | Outperformed |
| 4 | Century Therapeutics inc | 282.9% | Outperformed |
| 5 | Replimune Group Inc | 282.9% | Outperformed |
TTM share price return and U.S.A. 500 outperformance for Sqz Biotechnologies's best-performing tracked competitors requires a Commercial License.
Source: CSIMarket API, trailing 12 months.
Publicly Traded Peers of Sqz Biotechnologies Company
Revenue and income for trailing 12 months, in millions of $, except employees| Company | Market Cap | Revenues |
|---|---|---|
| Sqz Biotechnologies Company | 0.71 | 20.87 |
| Moderna Inc | 78,517.44 | 2,228.00 |
| Biontech Se | 23,947.64 | 3,214.29 |
| Krystal Biotech Inc | 10,333.86 | 440.48 |
| Apogee Therapeutics Inc | 10,190.15 | - |
| Immunitybio inc | 8,946.60 | 165.79 |
| SUBTOTAL | 167,573.95 | 8,921.09 |
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Sources: Sqz Biotechnologies Company's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Sqz Biotechnologies Company versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.
Sqz Biotechnologies's Business Segment Mix vs Peers
Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).| Company | Largest Segment |
|---|---|
| Immunitybio inc | Reportable 100.00 % |
| Novavax inc | Reportable 100.00 % |
| Immunocore Holdings Plc | Reportable 100.00 % |
| Ginkgo Bioworks Holdings Inc | Reportable 100.00 % |
| Prime Medicine Inc | Reportable 100.00 % |
Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).
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Sqz Biotechnologies's Productivity vs Peers Comparison
Revenue and income per employee, trailing 12 months, in $; market cap in millions of $| Company | Market Cap | Revenue / Employee | Income / Employee |
|---|---|---|---|
| Sqz Biotechnologies Company | 1 | 485,326 | -1,610,930 |
| Moderna Inc | 78,517 | 474,043 | -670,426 |
| Biontech Se | 23,948 | 411,719 | -162,986 |
| Krystal Biotech Inc | 10,334 | 1,493,166 | 818,525 |
| Apogee Therapeutics Inc | 10,190 | - | -1,127,866 |
| Immunitybio inc | 8,947 | 239,931 | -1,436,207 |
| PEERS TOTAL | 167,573 | 375,997 | -458,815 |
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Sqz Biotechnologies's Geographic Revenue Exposure vs Peers
Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.| Company | Largest Market |
|---|---|
| Krystal Biotech Inc | United States 75.19 % |
| Immunitybio inc | United States 98.99 % |
| Novavax inc | United States 68.88 % |
| 4d Molecular Therapeutics Inc | JP 97.05 % |
| Caribou Biosciences Inc | United States 94.16 % |
Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.
Sqz Biotechnologies's Position in Industry Market Structure
Market-capitalization share and concentration across all 159 companies in Sqz Biotechnologies's industry classification, broader than the peer set above. Market cap in millions of $.Sqz Biotechnologies ranks #154 of 159 companies by market capitalization in its industry, holding 0.00 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 1,331, indicating a unconcentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).
| Rank | Company | Market Cap | Industry Share |
|---|---|---|---|
| 1 | Amgen Inc | 226,707 | 26.02 % |
| 2 | Gilead Sciences Inc | 185,928 | 21.34 % |
| 3 | Moderna Inc | 76,517 | 8.78 % |
| 4 | Argenx Se | 63,326 | 7.27 % |
| 5 | Revolution Medicines Inc | 1,234 | 5.2% |
| 6 | Biogen Inc | 1,234 | 5.2% |
| 7 | Biontech Se | 1,234 | 5.2% |
| 8 | Exelixis Inc | 1,234 | 5.2% |
| 9 | Neurocrine Biosciences Inc | 1,234 | 5.2% |
| 10 | Halozyme Therapeutics Inc | 1,234 | 5.2% |
| 154 | Sqz Biotechnologies Company | 1 | 0.00 % |
Market cap and industry share for the rest of Sqz Biotechnologies's industry peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-25.
Sqz Biotechnologies's Same-Size Peers & Stock Performance
Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.| Rank | Company | Market Cap | TTM Return |
|---|---|---|---|
| 149 | Bioatla Inc | 2 | -95.49 % |
| 150 | Curis Inc | 2 | -50.82 % |
| 151 | Calidi Biotherapeutics Inc | 2 | -24.21 % |
| 152 | Nkgen Biotech Inc | 1 | - |
| 153 | Vivosim Labs Inc | 1,234 | 12.3% |
| 154 | Sqz Biotechnologies Company | 1 | - |
| 155 | Biomx Inc | 1,234 | 12.3% |
| 156 | Silexion Therapeutics Corp | 1,234 | 12.3% |
| 157 | Green Planet Bioengineering Co Ltd | 1,234 | 12.3% |
| 158 | Mymetics Corporation | 1,234 | 12.3% |
| 159 | Windtree Therapeutics Inc | 1,234 | 12.3% |
Market cap, return, momentum, beta and Sharpe ratio for the rest of Sqz Biotechnologies's same-size peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-09-28. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.
Sqz Biotechnologies's Valuation vs Competitive Position
Valuation multiples vs the Biotechnology & Pharmaceuticals industry average (93 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns.| Metric | Company | Industry Average | Difference |
|---|---|---|---|
| P/E | - | 26.7x | - |
| EV / EBITDA | - | 21.3x | - |
| P/B | 0.1x | 5.1x | -5.0x |
| Return on Equity | - | industry aggregate | - |
| Return on Invested Capital | -71.86 % | -6.17 % (avg) | -65.69 % |
Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.
Sqz Biotechnologies's BCG Growth-Share Matrix
Relative market share (vs Sqz Biotechnologies's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.
Sqz Biotechnologies falls in the Question Mark quadrant: relative market share of 0.00x vs its largest competitor, in an industry growing revenue 10.0% (median, trailing 12 months).
Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution.
Sqz Biotechnologies's Competitive Forces (Porter's Five Forces)
Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.| Force | Assessment | Basis |
|---|---|---|
| Competitive Rivalry | High | Industry HHI of 1,331 (see Industry Market Structure & Concentration above) |
| Supplier Power | Not covered on this page | See Sqz Biotechnologies's dedicated suppliers page for concentration and dependency data |
| Buyer Power | Not covered on this page | See Sqz Biotechnologies's dedicated customers page for concentration and dependency data |
| Threat of Substitutes | - | No systematic data source for cross-product substitution exists in this system; not estimated |
Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.
Sqz Biotechnologies's Industry Attractiveness & Competitive Strength
A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.
Sqz Biotechnologies falls in the Low attractiveness / Low strength cell: Harvest / Divest.
Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.
Sqz Biotechnologies's SWOT
Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.Strengths
No rule matched.
Weaknesses
- Low relative market share vs the industry leader (0.00x).
- Piotroski F-Score of 2 or below, the standard financial-distress signal.
Opportunities
- Industry revenue growing at a healthy 10.0% median pace.
- A meaningful share of tracked competitors (53.60 %) show financial-distress signals, a possible opening to gain share.
Threats
No rule matched.
Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.
Sqz Biotechnologies's Financial Strength vs Peers Comparison
Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months| Company | Quick Ratio | Working Capital | Debt / Equity |
|---|---|---|---|
| Sqz Biotechnologies Company | 2.60 | 2.86 | - |
| Moderna Inc | 0.86 | 2.88 | 0.07 |
| Biontech Se | 3.58 | 7.54 | - |
| Krystal Biotech Inc | 5.21 | 9.38 | - |
| Apogee Therapeutics Inc | 6.02 | 25.28 | - |
| Immunitybio inc | 1.63 | 5.83 | - |
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.
Sqz Biotechnologies's Revenue and Income Growth vs Peers
Quarterly revenue and net income growth, year over year and quarter over quarter| Company | Period | Revenue Y/Y | Income Y/Y |
|---|---|---|---|
| Sqz Biotechnologies Company | Q3 2023 | - | - |
| Moderna Inc | Q2 2026 | +2.1 % | - |
| Biontech Se | Q4 2025 | +4.3 % | - |
| Krystal Biotech Inc | Q2 2026 | +24.1 % | +42.9 % |
| Apogee Therapeutics Inc | Q2 2026 | - | - |
| Immunitybio inc | Q2 2026 | +93.9 % | - |
| PEERS TOTAL | +11.6 % | - |
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.
Sqz Biotechnologies's Peers' Costs of Sales and Capital Expenditures
Context for revenue growth: peer costs and capex, year over year and quarter over quarter| Company | Period | Costs Y/Y | Capex Y/Y |
|---|---|---|---|
| Sqz Biotechnologies Company | Q3 2023 | - | - |
| Moderna Inc | Q2 2026 | -21.8 % | +1,133.3 % |
| Biontech Se | Q4 2025 | +18.6 % | -38.9 % |
| Krystal Biotech Inc | Q2 2026 | - | +87.2 % |
| Apogee Therapeutics Inc | Q2 2026 | - | -99.2 % |
| Immunitybio inc | Q2 2026 | +119.1 % | +227.4 % |
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Sqz Biotechnologies's Returns and Turnover vs Peers
ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover| Company | ROA | ROI | ROE |
|---|---|---|---|
| Sqz Biotechnologies Company | - | - | - |
| Moderna Inc | - | - | - |
| Biontech Se | - | - | - |
| Krystal Biotech Inc | 17.65% | 19.16% | 19.34% |
| Apogee Therapeutics Inc | - | - | - |
| Immunitybio inc | - | - | - |
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).
Sqz Biotechnologies's Valuation vs Peers
P/E, price to sales, PEG, price to cash flow and price to book| Company | P/E | Price / Sales |
|---|---|---|
| Sqz Biotechnologies Company | - | 0.03 |
| Moderna Inc | - | 35.24 |
| Biontech Se | - | 7.45 |
| Krystal Biotech Inc | 42.14 | 23.46 |
| Apogee Therapeutics Inc | - | - |
| Immunitybio inc | - | 53.96 |
| PEERS AVERAGE | - | 18.78 |
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.