Celldex Therapeutics Inc's Competitiveness
A competitive positioning analysis and financial ratio benchmarking of Celldex Therapeutics Inc (CLDX) against its publicly traded competitors: sales growth, net income, profitability, valuation and market share, plus each peer's market capitalization, revenue, income and employees. Free below: the top 5 peers. Subscriber access adds the full competitor list and CSV downloads.
Key Findings: Celldex Therapeutics Inc vs Its Competitors
- TTM: Trailing 12-month revenue of 6M vs 355,868M combined for tracked competitors (0.0% combined share).
- Trending: Latest-quarter revenue run-rate is decelerating (-98.5% annualized vs trailing 12 months), vs accelerating (+4.6%) for its tracked peer group.
- Growth: Celldex Therapeutics Inc generated -97.0% revenue growth year over year in Q2 2026, vs 14.6% for its tracked competitors combined.
- Profitability: Its -334,104.6% net margin compares with 3.2% for the peer group.
- Scale: Celldex Therapeutics Inc ranks #4 of 19 companies by market capitalization in the In Vitro & In Vivo Diagnostic Substances industry, holding 4.2% of industry market cap.
- Peer revenue share: Celldex Therapeutics Inc accounted for 0.0% of combined revenue among its tracked peer group, up from 0.0% a year earlier.
- Peer differentiation: Revenue per employee of $0.03M compares with $1.16M for the peer group (0.0x).
Every figure above is sourced and cited in detail further down this page (Market Structure, Profitability & Cost Structure, Productivity vs Peers).
CLDX Sales vs. its Competitors, Q2 2026
Celldex Therapeutics Inc reported revenue contraction of 96.99 % year on year in Q2 2026, below its competitors' combined revenue growth of 14.62 %.
With a net margin of -334,104.55 %, Celldex Therapeutics Inc reported lower profitability than its competitors (3.16 %).
Celldex Therapeutics Inc generated 0.00 % of the combined sales of its peer group, up from 0.00 % a year earlier.
Celldex Therapeutics Inc vs. its Competitors, Q2 2026
Revenue growth, year on year
Net margin
Revenue run-rate vs trailing 12 months
TTM net margin
TTM = trailing twelve months. Run-rate annualizes the latest quarter (×4) and compares it to TTM. In millions of $. High-Confidence Competitors are named as a competitor directly in an SEC filing; Similar-Size Competitors are the closest peers by market-cap rank within the same industry; Similar Growth & Profitability Competitors are the closest peers by combined revenue growth, operating margin and ROIC, all independent of the competitor list.
TTM revenue, latest-quarter run-rate and net income/margin benchmarked across Celldex Therapeutics Inc and its 4 competitor groupings. Available under Commercial License.
| Entity | TTM Revenue | Rev Run-rate vs TTM |
|---|---|---|
| Celldex Therapeutics inc | $12,345M | +12.3% · Accelerating |
| Competitors combined | $12,345M | +12.3% · Accelerating |
| High-Confidence Competitors (5) | $12,345M | +12.3% · Accelerating |
| Similar-Size Competitors (8) | $12,345M | +12.3% · Accelerating |
TTM revenue, run-rate and net margin benchmarking across Celldex Therapeutics Inc's competitor groups requires a Commercial License.
For context: the In Vitro & In Vivo Diagnostic Substances industry grew revenue 2.5% year over year, combined, vs -97.0% for Celldex Therapeutics Inc. Celldex Therapeutics Inc's share of combined industry revenue moved from 0.02% to 0.00%, a loss of 0.02 percentage points.
Celldex Therapeutics Inc's Competitor Quality Breadth
Share of each group, trailing 12 months: profitable (net margin > 0), expanding (revenue growth > 0), growing faster than the industry's own median, and financially distressed (Piotroski F-Score of 2 or below).
| Entity | Profitable | Expanding | Above Industry Growth | Distressed |
|---|---|---|---|---|
| Celldex Therapeutics inc | - | - | - | Yes |
| Competitors combined (15) | ||||
| High-Confidence Competitors (5) | ||||
| Similar-Size Competitors (8) |
Source: CSIMarket API, trailing 12 months. Altman Z-Score is not shown here: it is not populated in the underlying data for any company. Percentages are of companies in each group that report the relevant metric, not of the full group size.
CLDX Stock Performance relative to its Competitors
CLDX Stock Performance relative to High-Confidence Competitors
CLDX Stock Performance relative to Similar-Size Competitors
5 Best-Performing Tracked Competitors, Trailing 12 Months
| # | Competitor | TTM Share Price Return | vs U.S.A. 500 |
|---|---|---|---|
| 1 | Merck and Co Inc | 282.9% | Outperformed |
| 2 | Eli Lilly And Company | 282.9% | Outperformed |
| 3 | Amgen Inc | 282.9% | Outperformed |
| 4 | Bristol myers Squibb Company | 282.9% | Outperformed |
| 5 | Vertex Pharmaceuticals Inc | 282.9% | Outperformed |
TTM share price return and U.S.A. 500 outperformance for Celldex Therapeutics Inc's best-performing tracked competitors requires a Commercial License.
Source: CSIMarket API, trailing 12 months.
Publicly Traded Peers of Celldex Therapeutics inc
Revenue and income for trailing 12 months, in millions of $, except employees| Company | Market Cap | Revenues |
|---|---|---|
| Celldex Therapeutics inc | 2,451.18 | 5.79 |
| Eli Lilly And Company | 1,058,837.89 | 79,665.80 |
| Merck and Co Inc | 367,264.30 | 66,569.00 |
| Novartis Ag | 287,150.40 | 56,674.00 |
| Amgen Inc | 227,462.72 | 38,095.00 |
| Gilead Sciences Inc | 189,197.03 | 30,457.00 |
| SUBTOTAL | 2,642,948.40 | 412,548.04 |
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Sources: Celldex Therapeutics inc's official press releases and regulatory filings; CSIMarket.com's market research; and the financial filings and press releases of the other companies cited.
Updated on:
Focus of this report: publicly traded companies. Ten additional tables on Celldex Therapeutics inc versus competitors, including market share analysis, are in the navigation menu under Competition. To download the tables, please subscribe.
Celldex Therapeutics Inc's Competitors Named by the Company
Competitive relationships identified from SEC filings and corroborating sources, each with a basis and confidence.| Competitor | Basis | Confidence |
|---|---|---|
| Pyxis Oncology Inc | Named by the company | 85% |
| Jasper Therapeutics Inc | Named by the company | 85% |
| Trevi Therapeutics Inc | Named by the company | 85% |
| Marker Therapeutics inc | Named by the company | 85% |
| Enanta Pharmaceuticals Inc | Named by the company | 85% |
Filing basis, confidence, active dates and source counts for Celldex Therapeutics Inc's named competitors require a Commercial License.
Methodology: relationships are extracted from SEC filings (named-competitor disclosures) and corroborating sources. Named by the company = explicitly disclosed as a competitor; Inferred = derived from corroborating signals. Confidence reflects evidence strength.
Celldex Therapeutics Inc's Business Segment Mix vs Peers
Revenue by operating segment or division, as named and reported by each company. Segment names are the filer's own and are not standardized across companies. Do not assume a same-named or similarly-named segment is defined identically between two companies. Shares are of each company's own total revenue and are not required to sum to 100% (intersegment revenue, unallocated items).| Company | Largest Segment |
|---|---|
| Eli Lilly And Company | Reportable 100.00 % |
| Merck and Co Inc | Pharmaceutical segment 88.88 % |
| Amgen Inc | Reportable 100.00 % |
| Pfizer Inc | U.S. Commercial Division 52.92 % |
| Vertex Pharmaceuticals Inc | Pharmaceuticals 100.00 % |
Source: operating segment revenue as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API, leaf-level reportable segments only (parent roll-up segments are excluded where sub-segments are separately disclosed).
Celldex Therapeutics Inc's Productivity vs Peers Comparison
Revenue and income per employee, trailing 12 months, in $; market cap in millions of $| Company | Market Cap | Revenue / Employee | Income / Employee |
|---|---|---|---|
| Celldex Therapeutics inc | 2,451 | 29,247 | -1,517,924 |
| Eli Lilly And Company | 1,058,838 | 1,593,316 | 534,224 |
| Merck and Co Inc | 367,264 | 887,587 | 42,267 |
| Novartis Ag | 287,150 | 752,973 | 185,566 |
| Amgen Inc | 227,463 | 2,930,385 | 672,538 |
| Gilead Sciences Inc | 189,197 | 1,791,588 | -190,588 |
| PEERS TOTAL | 2,640,497 | 1,164,357 | 200,598 |
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Celldex Therapeutics Inc's Geographic Revenue Exposure vs Peers
Revenue by country/region as reported in each company's most recent filing. Disclosure granularity varies by filer (some report by country, others by broad region) and is shown as disclosed.| Company | Largest Market |
|---|---|
| Eli Lilly And Company | United States 61.21 % |
| Merck and Co Inc | EMEA 23.60 % |
| Gilead Sciences Inc | United States 70.78 % |
| Pfizer Inc | United States 58.91 % |
| Vertex Pharmaceuticals Inc | United States 61.68 % |
Source: revenue geography as reported in each company's SEC filings (10-K/10-Q), via the CSIMarket API. Percentages are of that company's own total consolidated revenue for its most recent reported period.
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Celldex Therapeutics Inc's Position in Industry Market Structure
Market-capitalization share and concentration across all 18 companies in Celldex Therapeutics Inc's industry classification, broader than the peer set above. Market cap in millions of $.Celldex Therapeutics Inc ranks #4 of 18 companies by market capitalization in its industry, holding 4.21 % of total industry market cap. The industry's Herfindahl-Hirschman Index (HHI) is 5,377, indicating a highly concentrated market structure (U.S. antitrust guidance: below 1,500 unconcentrated, 1,500 to 2,500 moderately concentrated, above 2,500 highly concentrated).
| Rank | Company | Market Cap | Industry Share |
|---|---|---|---|
| 1 | Idexx Laboratories Inc | 41,961 | 72.03 % |
| 2 | Lantheus Holdings Inc | 6,734 | 11.56 % |
| 3 | Neogen Corporation | 2,984 | 5.12 % |
| 4 | Celldex Therapeutics inc | 2,451 | 4.21 % |
| 5 | Intellia Therapeutics Inc | 1,234 | 5.2% |
| 6 | Quidelortho Corp | 1,234 | 5.2% |
| 7 | Achieve Life Sciences Inc | 1,234 | 5.2% |
| 8 | Alpha Teknova Inc | 1,234 | 5.2% |
| 9 | Myriad Genetics Inc | 1,234 | 5.2% |
| 10 | Insight Molecular Diagnostics Inc | 1,234 | 5.2% |
Market cap and industry share for the rest of Celldex Therapeutics Inc's industry peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation) across CSIMarket's industry classification, market capitalization as of 2026-09-28.
Celldex Therapeutics Inc's Same-Size Peers & Stock Performance
Peers chosen by closeness in market-cap rank within the same industry classification (not the named-competitor list above). Trailing 12-month total return, 3-month price momentum, beta and Sharpe ratio vs the broad U.S. market.| Rank | Company | Market Cap | TTM Return |
|---|---|---|---|
| 1 | Idexx Laboratories Inc | 41,961 | -16.07 % |
| 2 | Lantheus Holdings Inc | 6,734 | 94.20 % |
| 3 | Neogen Corporation | 2,984 | 158.21 % |
| 4 | Celldex Therapeutics inc | 2,451 | 21.44 % |
| 5 | Intellia Therapeutics Inc | 1,234 | 12.3% |
| 6 | Quidelortho Corp | 1,234 | 12.3% |
| 7 | Achieve Life Sciences Inc | 1,234 | 12.3% |
| 8 | Alpha Teknova Inc | 1,234 | 12.3% |
| 9 | Myriad Genetics Inc | 1,234 | 12.3% |
Market cap, return, momentum, beta and Sharpe ratio for the rest of Celldex Therapeutics Inc's same-size peers requires a Commercial License.
Source: CSIMarket API (daily market-structure computation); returns and risk metrics as of 2026-09-28. Beta and Sharpe ratio are versus the broad U.S. equity market, not this industry.
Celldex Therapeutics Inc's Valuation vs Competitive Position
Valuation multiples vs the In Vitro & In Vivo Diagnostic Substances industry average (18 companies, excluding loss-making/negative-equity outliers), alongside returns on capital for context on whether a premium or discount lines up with measurably stronger or weaker returns.| Metric | Company | Industry Average | Difference |
|---|---|---|---|
| P/E | - | 52.0x | - |
| EV / EBITDA | - | 16.5x | - |
| P/B | 4.6x | 4.6x | -0.1x |
| Return on Equity | -52.35 % | industry aggregate | -48.97 % |
| Return on Invested Capital | -28.26 % | 0.79 % (avg) | -29.05 % |
Source: CSIMarket API, trailing 12 months. A valuation premium or discount is not, by itself, a judgment of over- or under-valuation. Compare it against the return and growth context shown elsewhere on this page.
Celldex Therapeutics Inc's Multi-Year Financial Trajectory
Fiscal-year revenue growth, operating margin, return on invested capital and P/E, as reported in SEC filings.| Metric | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|
| Revenue Growth | -25.15 % | -62.54 % | 107.61 % | -37.30 % | -49.32 % | 192.02 % | 1.99 % | - |
| Operating Margin | -1,640.13 % | -1,540.19 % | -854.06 % | -1,531.78 % | -4,889.01 % | -2,245.27 % | -2,778.89 % | - |
| Return on Invested Capital | -55.14 % | -24.05 % | -16.05 % | -11.40 % | -15.87 % | -24.38 % | -12.21 % | -23.06 % |
| P/E | - | - | - | - | - | - | - | - |
Source: CSIMarket API, fiscal-year figures. P/E is this company's own historical ratio at each fiscal year end and can swing sharply around an earnings trough: that is real, not a data error.
Celldex Therapeutics Inc's BCG Growth-Share Matrix
Relative market share (vs Celldex Therapeutics Inc's largest competitor by market cap) against industry revenue growth, using the standard textbook thresholds (1.0x share, 10% growth) a common framework, not a precision instrument.
Celldex Therapeutics Inc falls in the Dog quadrant: relative market share of 0.06x vs its largest competitor, in an industry growing revenue -1.2% (median, trailing 12 months).
Source: CSIMarket API (market-cap share and industry revenue growth). The 10% growth and 1.0x share lines are standard textbook thresholds, not derived from this industry's own distribution. A caveat worth reading alongside this chart: Idexx Laboratories Inc alone holds 72% of this industry's market cap. In an industry this dominated by one leader, the framework will place nearly every OTHER company in "Dog" or "Question Mark" purely because relative share is measured against that leader, regardless of how strong those other companies actually are on their own fundamentals. Check the Profitability, Valuation and Financial Strength sections above before treating this quadrant label as a verdict.
Celldex Therapeutics Inc's Competitive Forces (Porter's Five Forces)
Only the forces this data can support honestly are shown; the other three are marked as such rather than guessed.| Force | Assessment | Basis |
|---|---|---|
| Competitive Rivalry | Low | Industry HHI of 5,377 (see Industry Market Structure & Concentration above) |
| Supplier Power | Not covered on this page | See Celldex Therapeutics Inc's dedicated suppliers page for concentration and dependency data |
| Buyer Power | Not covered on this page | See Celldex Therapeutics Inc's dedicated customers page for concentration and dependency data |
| Threat of Substitutes | - | No systematic data source for cross-product substitution exists in this system; not estimated |
Note: this is a partial, data-grounded application of the framework, not a complete strategic assessment. Rivalry and barriers-to-entry readings are mechanical translations of the HHI and capital-intensity figures shown elsewhere on this page, not independent judgments.
Celldex Therapeutics Inc's Industry Attractiveness & Competitive Strength
A CSIMarket composite, not a standard field: each axis is an equal-weighted average of three factors already shown elsewhere on this page (industry growth, industry profitability and rivalry for attractiveness; relative market share, profitability and growth vs industry for strength). Disclosed as a designed methodology, not a precision measurement.
Celldex Therapeutics Inc falls in the Medium attractiveness / Low strength cell: Harvest.
Source: CSIMarket API, trailing 12 months. Each axis score is a simple 1(low)/2(medium)/3(high) average across its three inputs -- a transparent, disclosed simplification, not a validated academic scoring model.
Celldex Therapeutics Inc's SWOT
Every point below is a fixed rule applied to a metric already shown elsewhere on this page (Market Structure, Profitability, Valuation, Run-Rate, Stock Performance, Quality Breadth) not an independent strategic assessment. A blank quadrant means no rule was met, not that none apply.Strengths
- Outperforming the U.S.A. 500 over the trailing 12 months.
Weaknesses
- Return on equity 49.0 points below the industry aggregate.
- Latest-quarter revenue run-rate is decelerating (-98.5% annualized vs trailing 12 months).
- Low relative market share vs the industry leader (0.06x).
- Piotroski F-Score of 2 or below, the standard financial-distress signal.
Opportunities
No rule matched.
Threats
- Industry dominated by Idexx Laboratories Inc, holding 72.03 % of industry market cap.
Methodology: mechanical, rule-based SWOT. Each bullet reuses a figure already sourced and cited elsewhere on this page; nothing here is generated narrative or independent analyst judgment.
Celldex Therapeutics Inc's Financial Strength vs Peers Comparison
Quick ratio, working capital, debt to equity and asset turnover, trailing 12 months| Company | Quick Ratio | Working Capital | Debt / Equity |
|---|---|---|---|
| Celldex Therapeutics inc | 0.70 | 11.05 | - |
| Eli Lilly And Company | 0.20 | 1.48 | 1.59 |
| Merck and Co Inc | 0.40 | 1.46 | 1.01 |
| Novartis Ag | 0.42 | 1.12 | 0.02 |
| Amgen Inc | 0.46 | 1.26 | 5.86 |
| Gilead Sciences Inc | - | 1.54 | 1.27 |
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Quick ratio = cash / current liabilities; working capital ratio = current assets / current liabilities; asset turnover = revenue / total assets. Peers in the Blank Checks industry are excluded.
Celldex Therapeutics Inc's Revenue and Income Growth vs Peers
Quarterly revenue and net income growth, year over year and quarter over quarter| Company | Period | Revenue Y/Y | Income Y/Y |
|---|---|---|---|
| Celldex Therapeutics inc | Q2 2026 | -97.0 % | - |
| Eli Lilly And Company | Q2 2026 | +47.7 % | +25.3 % |
| Merck and Co Inc | Q2 2026 | +5.1 % | - |
| Novartis Ag | Q4 2025 | +9.6 % | +17.0 % |
| Amgen Inc | Q2 2026 | +9.5 % | +65.9 % |
| Gilead Sciences Inc | Q2 2026 | +10.2 % | - |
| PEERS TOTAL | +12.8 % | -46.8 % |
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Growth is shown only where both periods are positive. Peers in the Blank Checks industry are excluded.
Celldex Therapeutics Inc's Peers' Costs of Sales and Capital Expenditures
Context for revenue growth: peer costs and capex, year over year and quarter over quarter| Company | Period | Costs Y/Y | Capex Y/Y |
|---|---|---|---|
| Celldex Therapeutics inc | Q2 2026 | - | +336.7 % |
| Eli Lilly And Company | Q2 2026 | +33.5 % | +72.8 % |
| Merck and Co Inc | Q2 2026 | +23.6 % | +16.9 % |
| Novartis Ag | Q4 2025 | +18.3 % | +13.3 % |
| Amgen Inc | Q2 2026 | -6.6 % | +39.0 % |
| Gilead Sciences Inc | Q2 2026 | +5.2 % | +30.8 % |
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Celldex Therapeutics Inc's Returns and Turnover vs Peers
ROA, ROI and ROE (trailing 12 months), receivables and inventory turnover| Company | ROA | ROI | ROE |
|---|---|---|---|
| Celldex Therapeutics inc | - | - | - |
| Eli Lilly And Company | 21.97% | 33.95% | 92.54% |
| Merck and Co Inc | 2.42% | 3.24% | 6.59% |
| Novartis Ag | 12.59% | 12.62% | 30.00% |
| Amgen Inc | 9.48% | 13.08% | 89.32% |
| Gilead Sciences Inc | - | - | - |
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ROA = net income / total assets; ROI = net income / investments; ROE = net income / equity; turnover ratios use trailing 12 month revenue (receivables) and cost of sales (inventory).
Celldex Therapeutics Inc's Valuation vs Peers
P/E, price to sales, PEG, price to cash flow and price to book| Company | P/E | Price / Sales |
|---|---|---|
| Celldex Therapeutics inc | - | 423.27 |
| Eli Lilly And Company | 39.77 | 13.29 |
| Merck and Co Inc | 119.91 | 5.52 |
| Novartis Ag | 20.53 | 5.07 |
| Amgen Inc | 25.97 | 5.97 |
| Gilead Sciences Inc | - | 6.21 |
| PEERS AVERAGE | 37.34 | 6.41 |
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P/E = price / diluted EPS (trailing 12 months); PEG = P/E divided by EPS growth; the average row divides the peers' combined market cap by their combined income, sales, cash flow and equity.