Taysha Gene Therapies Inc (TSHA) Return on Investment ROI from the second quarter of 2026 to second quarter of 2025 and for the year 2026, average high and low, overall ranking from Jun 30 2026 to Jun 30 2025 - CSIMarket
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Taysha Gene Therapies Inc   (NASDAQ: TSHA)


Taysha Gene Therapies Inc's ROI from its second quarter of 2026 to the second quarter of 2025 and 5 Year Period

Return on Investment, Quarterly Results, Trends, Rankings, Statistics

What is Taysha Gene Therapies Inc's ROI in the second quarter of 2026?
Taysha Gene Therapies Inc recorded a cumulative net loss of $-150 million during 12 months ending in the second quarter of 2026, resulting in a negative return on investment (ROI) of -45.02%.

Within the Healthcare sector 431 other companies had a higher return on investment. While return on investment, the total ranking has deteriorated compared to the first quarter of 2026 from 3377 to 3634.

Definition and Formula of Return on Investment



Return On Investment (Jun 30 2026)
II. Quarter
(Mar 31 2026)
I. Quarter
(Dec 31 2025)
IV. Quarter
(Sep 30 2025)
III. Quarter
(Jun 30 2025)
II. Quarter
Y / Y Investment Change TTM 97.33 % 132.18 % 108.26 % 67.68 % 88.61 %
Y / Y Net Income Change TTM - - - - -
Investment (TTM) in Millions 444 280 317 288 308
Return On Investment (TTM) -45.02 % -43.55 % -42.39 % -48.25 % -55.05 %
TSHA's Overall Ranking # 3634 # 3377 # 3249 # 2726 # 3066
Seq. Investment Change TTM 11.44 % 15.99 % 24.14 % 22.98 % 31.12 %
Seq. Net Income Change TTM - - - - -
Net Income (TTM) in Millions -150 -130 -109 -100 -93




Return On Investment TSHA's Ranking
Within: No.
Industry # 62
Sector # 432
Overall # 3634

Return On Investment Statistics
High Average Low
-16.05 %
-115.77 %
-548.37 %
(Sep 30 2024)   (Sep 30 2023)



  News about Taysha Gene Therapies Inc Return on Investment ROI

Taysha Gene Therapies Strives for Talent Amidst Financial Turmoil: A Path to Recovery or a Risky Gamble,

November 1, 2024

Taysha Gene Therapies: A Balancing Act Between Talent Acquisition and Financial StrugglesIn the ever-evolving landscape of biotechnology, Taysha Gene Therapies, Inc. (NASDAQ: TSHA) has recently taken center stage for a series of significant moves that highlight both ambition and concern. On November 1, 2024, the company’s Compensation Committee granted stock options amounting to 157,000 shares to three new employees, a decision rooted in its 2023 Inducement Plan and guided by Nasdaq Listing Rule 5635(c)(4). This latest incentive follows a broader trend at Taysha, which has made multiple inducement grants this year to attract and retain talent amidst mounting financial difficulties.These grants are not merely administrative gestures; they are critical tools for biotechnology firms like Taysha that are navigating the dual challenges of recruitment and fiscal health. The company’s recent history paints a stark picture: a cumulative net loss of $114 million in the 12 months ending in the second quarter of 2024 has resulted in a staggering negative return on investment (ROI) of -128.04%. This performance places Taysha at a disadvantage compared to its peers in the healthcare sector, where 695 other companies boast significantly higher ROI figures.

Taysha Gene Therapies Grants Inducement Options to New Employees in Effort to Advance CNS Gene Therapies – Share Price Sees Q3 Dip

August 2, 2024



Taysha Gene Therapies, a prominent clinical-stage biotechnology company specializing in adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central nervous system (CNS), has made a significant announcement today. On August 1, 2024, the Compensation Committee of Taysha s Board of Directors approved the issuance of options to purchase a total of 356,000 shares of the company s common stock to two newly recruited employees.
The stock options were granted under the Taysha Gene Therapies, Inc. 2023 Inducement Plan and are considered a material inducement to attract and retain talented individuals in accordance with Nasdaq Listing Rule 5635(c)(4).

Taysha Gene Therapies: Struggles in the Gene Therapy Market Amidst Inducement Grants and Financial Setbacks

July 5, 2024



Taysha Gene Therapies, a clinical-stage biotech company specializing in gene therapies for severe monogenic diseases of the central nervous system, has recently made significant announcements regarding its operations. On July 3, 2024, the company granted four new employees options to purchase 484,000 shares of its common stock as an inducement for their recruitment. Meanwhile, Taysha Gene Therapies faced considerable financial difficulties, incurring a net loss of $215 million during the 12-month period ending in the third quarter of 2023. This negative return on investment (ROI) of -1104.79% raises concerns about the company s financial stability and overall performance. Let s delve into these facts and assess their impact on Taysha Gene Therapies.
Financial Challenges and Negative ROI:
The company recorded a cumulative net loss of $215 million during the 12 months ending in the third quarter of 2023, resulting in an alarming negative ROI of -1104.79%. This signifies that for every dollar investors put into the company during that period, they lost over 11 times that amount. It is evident that Taysha Gene Therapies faced significant financial difficulties, which can cast doubts on its long-term viability and ability to deliver returns to shareholders. The extent of these financial challenges raises concerns about the company s financial management, strategic decisions, and market performance.

Taysha Gene Therapies Provides Update on Deprioritized Pipeline Programs: An Effort to Enhance Development Potential

February 15, 2024


Introduction
Taysha Gene Therapies, Inc. (Nasdaq: TSHA), a prominent clinical-stage gene therapy company specializing in AAV-based gene therapies for central nervous system (CNS) monogenic diseases, has recently shared an update on its deprioritized pipeline programs. The company aims to provide further support and opportunities for the potential development of these programs in its ongoing efforts. Despite recording a cumulative net loss of $-215 million during the 12 months ending in the third quarter of 2023, resulting in a negative return on investment (ROI) of -1104.79%, Taysha Gene Therapies Inc shares continue to trade on the NASDAQ slightly above its 52-week average.
The Deprioritized Pipeline Programs
Taysha Gene Therapies Inc is committed to developing groundbreaking AAV-based gene therapies for the treatment of monogenic disorders of the CNS. However, due to various reasons such as limited resources, strategic focus adjustment, or lack of promising results in preclinical or clinical trials, some programs have been classified as deprioritized. Instead of altogether abandoning these programs and their potential, Taysha Gene Therapies Inc has sought to explore further options for their development.






Financial Statements
Taysha Gene Therapies Inc's II. Quarter Investments $ 444 Millions TSHA's Balance sheet
Taysha Gene Therapies Inc's II. Quarter Income $ -47 Millions Quarterly TSHA's Income Statement
TSHA's Income by Division See TSHA's Income by Division


TSHA Annual Return On Investment (Dec 31 2025)
2025
(Dec 31 2024)
2024
(Dec 31 2023)
2023
(Dec 31 2022)
2022
(Dec 31 2021)
2021
Total Investments in Millions 299 117 117 43 162
Y / Y Investment Growth 155.7 % -0.21 % 171.85 % -73.46 % -35.57 %
Net Income in Millions -109 -89 -112 -166 -175
Y / Y Net Income Growth - - - - -
Annual Return On Investment -36.5 % -76.47 % -95.34 % -385.67 % -107.59 %


Annual Roi Comment


Definition and Formula of Return on Investment

Other ROI Ratios
Biotechnology & Pharmaceuticals Industry Roi Trends and Statistics
Healthcare Sector Return On Investment Statistics
Roi Trends for overall market
TSHA's Roi Ratio versus Biotechnology & Pharmaceuticals Industry, Healthcare Sector and total Market
Highest Ranking Return On Investment
Lowest Ranking Return On Investment
Subscribers only: Roi for TSHA's Competitors
Subscribers only: Roi for Taysha Gene Therapies Inc's Suppliers
Subscribers only: Return On Investment for TSHA's Customers

Other Ratios
TSHA's Roa TSHA's Inventory Turnover Ratio TSHA's Growth Rates TSHA's Dividend Statistics
TSHA's Profitability Ratios TSHA's Asset Turnover Ratio TSHA's Dividend Growth
TSHA's Roe TSHA's Valuation Ratios TSHA's Financial Strength Ratios TSHA's Dividend Payout Ratio



Companies with similar Return On Investment at Jun 30 2026, within Healthcare Sector ROI


Date modified: 2026-09-26T07:38:37+00:00



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