Ultragenyx Pharmaceutical Inc (RARE) Return on Investment ROI from the second quarter of 2026 to second quarter of 2025 and for the year 2026, average high and low, overall ranking from Jun 30 2026 to Jun 30 2025 - CSIMarket
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Ultragenyx Pharmaceutical Inc   (NASDAQ: RARE)


Ultragenyx Pharmaceutical Inc's ROI from its second quarter of 2026 to the second quarter of 2025 and 5 Year Period

Return on Investment, Quarterly Results, Trends, Rankings, Statistics

What is Ultragenyx Pharmaceutical Inc's ROI in the second quarter of 2026?
Ultragenyx Pharmaceutical Inc recorded a cumulative net loss of $-586 million during 12 months ending in the second quarter of 2026, resulting in a negative return on investment (ROI) of -56.99%.

Within the Healthcare sector 298 other companies had a higher return on investment. While return on investment, the total ranking has deteriorated compared to the first quarter of 2026 from 2090 to 3460.

Definition and Formula of Return on Investment



Return On Investment (Jun 30 2026)
II. Quarter
(Mar 31 2026)
I. Quarter
(Dec 31 2025)
IV. Quarter
(Sep 30 2025)
III. Quarter
(Jun 30 2025)
II. Quarter
Y / Y Investment Change TTM -10.38 % -11.51 % -10.08 % -12.46 % -0.27 %
Y / Y Net Income Change TTM - - - - -
Investment (TTM) in Millions 913 1,043 1,229 928 1,089
Return On Investment (TTM) -56.99 % -56.79 % -53.07 % -54.39 % -46.45 %
RARE's Overall Ranking # 3460 # 2090 # 2628 # 3036 # 2811
Seq. Investment Change TTM -4.1 % -1.04 % 1.63 % -7.09 % -5.3 %
Seq. Net Income Change TTM - - - - -
Net Income (TTM) in Millions -586 -609 -575 -580 -533




Return On Investment RARE's Ranking
Within: No.
Industry # 114
Sector # 299
Overall # 3460

Return On Investment Statistics
High Average Low
-12.33 %
-35.12 %
-70.29 %
(Mar 31 2021)   (Dec 31 2017)



  News about Ultragenyx Pharmaceutical Inc Return on Investment ROI

Ultragenyx Achieves Breakthrough Therapy Status for Osteogenesis Imperfecta as OKX Explorer Enhances Web3 Analytics with Bitlayer Integration

October 7, 2024

In a significant stride for patients with rare bone disorders, Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE), a company committed to innovating treatments for rare and ultra-rare diseases, has proudly announced that it has been granted Breakthrough Therapy Designation by the U.S. Food and Drug Administration (FDA) for its investigational drug, setrusumab (UX143). This therapy targets the reduction of fracture risk in patients suffering from osteogenesis imperfecta (OI) Types I, III, or IV, specifically in individuals aged two years and older. The FDA s designation underscores the potential of setrusumab to provide a meaningful therapeutic advancement for patients who face the daily challenges posed by this brittle bone disorder, which is characterized by fragile bones and an increased susceptibility to fractures.Setrusumab s designation as a Breakthrough Therapy reflects the recognition of the urgent medical need for effective treatments in the field of osteogenesis imperfecta. OI affects children and adults alike, presenting significant health burdens and disrupting normal activities of life. By targeting the genetic and molecular basis of OI, setrusumab aims to not only decrease the frequency of fractures but also to enhance the overall quality of life for patients and their families.

OKX Explorer Expands Capabilities with Bitlayer Support, Enhancing Web3 Analytics

September 3, 2024

On September 3, 2024, OKX Explorer, a prominent blockchain search engine and analytics platform, announced the integration of support for Bitlayer, a platform designed for the management and analysis of blockchain data. This new addition aims to bolster the capabilities of OKX Explorer, allowing users to leverage advanced tools for navigating and understanding the complexities of blockchain networks.OKX Explorer is widely recognized for its user-friendly interface and robust functionality, offering a comprehensive suite of tools for both casual users and industry professionals. The platform provides real-time data, transaction tracking, and blockchain analytics, making it an essential resource for stakeholders in the evolving landscape of decentralized finance and Web3 applications.

Ultragenyx Induces Growth 12 New Executives Boost Talent Pool with 37,975 Restricted Stock Units,

August 21, 2024

Ultragenyx Welcomes New Talent with Stock Incentives: A Strategic Move in the Biopharmaceutical SectorIn a significant move to enhance its workforce, Ultragenyx Pharmaceutical Inc. a leading biopharmaceutical company dedicated to developing novel therapies for rare and ultrarare diseases, has announced the grant of 37,975 restricted stock units (RSUs) to 12 newly hired non-executive officers. This strategic inducement aligns with the company s goals of fostering innovation and ensuring that it remains competitive in the challenging field of rare disease treatment. The grant, approved by the compensation committee of Ultragenyx’s board of directors, reflects a commitment to attracting top talent essential for advancing the company’s mission. Details of the Inducement Grant On August 21, 2024, Ultragenyx disclosed the inducement grant under Nasdaq Listing Rule 5635(c)(4). This rule permits companies to grant equity awards to new employees as an incentive for their contributions from the onset of their employment. The RSUs were granted as part of the Ultragenyx Employment Inducement Plan, which is designed to incentivize incoming personnel, thereby motivating them to contribute to the company’s vision and strategy from the very beginning.

Ultragenyx's Groundbreaking Milestones in Sanfilippo Syndrome Treatment Amidst Financial Revival

June 12, 2024



In a groundbreaking development, Ultragenyx Pharmaceutical Inc has recently announced its plans to file for accelerated approval of UX111 for the treatment of Sanfilippo Syndrome Type A (MPS IIIA). This announcement comes as the company reached an agreement with the FDA regarding the use of cerebral spinal fluid (CSF) heparan sulfate (HS) as a surrogate marker for accelerated approval. These milestones carry significant implications for the company s future and the patients affected by this devastating disease.
Expansion into Sanfilippo Syndrome Treatment:
Sanfilippo Syndrome, also known as MPS IIIA, is a rare and severe genetic disorder that primarily affects the brain and nervous system of children. There is currently no approved treatment for this condition, leaving families with limited options. Ultragenyx s decision to file for accelerated approval of UX111 demonstrates their commitment to addressing unmet medical needs in the rare disease space.






Financial Statements
Ultragenyx Pharmaceutical Inc's II. Quarter Investments $ 913 Millions RARE's Balance sheet
Ultragenyx Pharmaceutical Inc's II. Quarter Income $ -92 Millions Quarterly RARE's Income Statement
RARE's Income by Division See RARE's Income by Division


RARE Annual Return On Investment (Dec 31 2025)
2025
(Dec 31 2024)
2024
(Dec 31 2023)
2023
(Dec 31 2022)
2022
(Dec 31 2021)
2021
Total Investments in Millions 1,148 1,159 1,211 1,284 1,341
Y / Y Investment Growth -0.97 % -4.24 % -5.74 % -4.24 % -14.58 %
Net Income in Millions -575 -569 -607 -707 -454
Y / Y Net Income Growth - - - - -
Annual Return On Investment -50.09 % -49.1 % -50.11 % -55.09 % -33.86 %


Annual Roi Comment


Definition and Formula of Return on Investment

Other ROI Ratios
Major Pharmaceutical Preparations Industry Roi Trends and Statistics
Healthcare Sector Return On Investment Statistics
Roi Trends for overall market
RARE's Roi Ratio versus Major Pharmaceutical Preparations Industry, Healthcare Sector and total Market
Highest Ranking Return On Investment
Lowest Ranking Return On Investment
Subscribers only: Roi for RARE's Competitors
Subscribers only: Roi for Ultragenyx Pharmaceutical Inc's Suppliers
Subscribers only: Return On Investment for RARE's Customers

Other Ratios
RARE's Roa RARE's Inventory Turnover Ratio RARE's Growth Rates RARE's Dividend Statistics
RARE's Profitability Ratios RARE's Asset Turnover Ratio RARE's Dividend Growth
RARE's Roe RARE's Valuation Ratios RARE's Financial Strength Ratios RARE's Dividend Payout Ratio



Companies with similar Return On Investment at Jun 30 2026, within Healthcare Sector ROI


Date modified: 2026-09-11T09:54:08+00:00



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