Kalvista Pharmaceuticals Inc (KALV) Return on Investment ROI from the first quarter of 2026 to first quarter of 2025 and for the year 2026, average high and low, overall ranking from Mar 31 2026 to Jan 31 2025 - CSIMarket
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Kalvista Pharmaceuticals Inc   (NASDAQ: KALV)


Kalvista Pharmaceuticals Inc's ROI from its first quarter of 2026 to the first quarter of 2025 and 5 Year Period

Return on Investment, Quarterly Results, Trends, Rankings, Statistics

What is Kalvista Pharmaceuticals Inc's ROI in the first quarter of 2026?
Kalvista Pharmaceuticals Inc recorded a cumulative net loss of $-185 million during 12 months ending in the first quarter of 2026, resulting in a negative return on investment (ROI) of -91.57%.

Within the Healthcare sector 609 other companies had a higher return on investment. While return on investment, the total ranking has deteriorated compared to the third quarter of 2025 from 2606 to 3340.

Definition and Formula of Return on Investment



Return On Investment (Mar 31 2026)
I. Quarter
(Sep 30 2025)
III. Quarter
(Jul 31 2025)
I. Quarter
(Apr 30 2025)
IV. Quarter
(Jan 31 2025)
III. Quarter
Y / Y Investment Change TTM 12.4 % 3.69 % 10.82 % -10.39 % 15.62 %
Y / Y Net Income Change TTM - - - - -
Investment (TTM) in Millions 268 206 295 41 207
Return On Investment (TTM) -91.57 % -112.47 % -108.47 % -124.77 % -97.69 %
KALV's Overall Ranking # 3340 # 2606 # 3748 # 3981 #
Seq. Investment Change TTM 8.21 % -0.13 % 27.35 % -18.33 % -0.18 %
Seq. Net Income Change TTM - - - - -
Net Income (TTM) in Millions -185 -210 -203 -183 -176




Return On Investment KALV's Ranking
Within: No.
Industry # 278
Sector # 610
Overall # 3340

Return On Investment Statistics
High Average Low
-17.72 %
-58.73 %
-187.77 %
(Jan 31 2019)   (Jul 31 2025)



  News about Kalvista Pharmaceuticals Inc Return on Investment ROI

KalVista Pharmaceuticals Secures $179 Million Synthetic Royalty Financing to Advance Sebe Commercialization,

November 4, 2024

In a strategic move to finance its upcoming product launch, KalVista Pharmaceuticals, Inc. has closed a significant synthetic royalty financing agreement with DRI Healthcare Trust. This agreement, totaling up to $179 million, is designed to support the commercialization of KalVista’s cutting-edge drug, designated as ‘sebe.’ Overview of the Agreement The financing comprises an upfront payment of $100 million, a one-time optional payment of $22 million contingent upon U.S. product approval, and an additional $57 million tied to sales-based milestones. This structured financing approach allows KalVista to access substantial capital while avoiding the dilution typically associated with equity financing, thus preserving shareholder value. The strategic partnership with DRI Healthcare Trust signals confidence in KalVista s business model and long-term potential of sebe as it inches closer to market entry. Role of DRI Healthcare Trust DRI Healthcare Trust has emerged as a key player in the healthcare investment space, focusing on royalty-based structures that provide non-dilutive funding solutions for life sciences companies. By entering into this synthetic royalty arrangement, DRI gains access to a revenue stream based on the future success of KalVista s product without taking an equity stake in the company. This alignment of interests allows KalVista to innovate and commercialize its product without the pressure that equity financing might introduce, enabling the company to concentrate on operational execution and market readiness.

Balancing Progress and Challenges Sebetralstats Potential in HAE and KalVista’s Financial Landscape

October 7, 2024

Recent developments in the management of hereditary angioedema (HAE) have seen the emergence of sebetralstat as a promising treatment option. KalVista Pharmaceuticals presented compelling data at the HAEi Global Angioedema Forum, highlighting the medication s potential in alleviating anxiety associated with HAE attacks. However, the company continues to grapple with significant financial challenges, including a substantial net loss. This article provides a outlook on KalVista s recent clinical findings alongside the company’s current financial standing.Hereditary angioedema (HAE) is a rare genetic condition characterized by recurrent episodes of severe swelling and can lead to considerable psychological stress for affected individuals. To address the urgent need for effective management strategies, KalVista Pharmaceuticals has been developing sebetralstat, a potential new therapy. The recent presentation at the HAEi Global Angioedema Forum provided new insights into its efficacy, particularly regarding the reduction of anxiety during HAE attacks. However, the financial implications of these developments cannot be overlooked, as KalVista has reported significant cumulative net losses and a declining return on investment.

KalVista Pharmaceuticals Appoints Benjamin L. Palleiko as CEO to Drive Growth and Overcome Challenges

March 7, 2024



KalVista Pharmaceuticals, a clinical stage pharmaceutical company specializing in oral, small molecule protease inhibitors, has recently announced the appointment of Benjamin L. Palleiko as its new Chief Executive Officer (CEO). This crucial leadership change comes at a challenging time for KalVista, as the company experienced a significant decline in its share value over the past month and recorded a substantial net loss in the past year. With Palleiko s appointment and Andrew Crockett s resignation, KalVista aims to tackle these obstacles head-on and ensure a more promising future.
A Shift in Leadership Strategy:
Effective immediately, Benjamin L. Palleiko transitions from his previous roles as President, Chief Business Officer (CBO), and Chief Financial Officer (CFO) to the position of CEO. Palleiko, a seasoned executive with an extensive background in the pharmaceutical industry, will steer the company in its mission to discover, develop, and commercialize novel therapies to address unmet medical needs.






Financial Statements
Kalvista Pharmaceuticals Inc's I. Quarter Investments $ 268 Millions KALV's Balance sheet
Kalvista Pharmaceuticals Inc's I. Quarter Income $ -23 Millions Quarterly KALV's Income Statement
KALV's Income by Division See KALV's Income by Division


KALV Annual Return On Investment (Apr 30 2025)
2025
(Apr 30 2024)
2024
(Apr 30 2023)
2023
(Apr 30 2022)
2022
(Apr 30 2021)
2021
Total Investments in Millions 95 207 161 185 257
Y / Y Investment Growth -53.82 % 28.29 % -13 % -28.03 % 203.26 %
Net Income in Millions -183 -127 -93 -82 -46
Y / Y Net Income Growth - - - - -
Annual Return On Investment -192.31 % -61.3 % -57.7 % -44.49 % -17.98 %


Annual Roi Comment


Definition and Formula of Return on Investment

Other ROI Ratios
Major Pharmaceutical Preparations Industry Roi Trends and Statistics
Healthcare Sector Return On Investment Statistics
Roi Trends for overall market
KALV's Roi Ratio versus Major Pharmaceutical Preparations Industry, Healthcare Sector and total Market
Highest Ranking Return On Investment
Lowest Ranking Return On Investment
Subscribers only: Roi for KALV's Competitors
Subscribers only: Roi for Kalvista Pharmaceuticals Inc's Suppliers
Subscribers only: Return On Investment for KALV's Customers

Other Ratios
KALV's Roa KALV's Inventory Turnover Ratio KALV's Growth Rates KALV's Dividend Statistics
KALV's Profitability Ratios KALV's Asset Turnover Ratio KALV's Dividend Growth
KALV's Roe KALV's Valuation Ratios KALV's Financial Strength Ratios KALV's Dividend Payout Ratio



Companies with similar Return On Investment at Mar 31 2026, within Healthcare Sector ROI


Date modified: 2026-09-26T07:07:31+00:00



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