PainReform CEO Ilan Hadar Discusses PRF-110's Potential in Combating the Opioid Epidemic

Published / Modified May 08 2024
CSIMarket Team / CSIMarket.com


In a recent interview with Proactiveinvestors.com, PainReform Ltd.'s CEO, Ilan Hadar, shed light on the latest developments surrounding PRF-110 and its potential to address the concerning opioid epidemic. As a clinical-stage specialty pharmaceutical company, PainReform focuses on reformulating established therapeutics to provide safer and more effective solutions for pain management. This article explores the key insights shared by Hadar and highlights the significance of PRF-110 in tackling the current opioid crisis.

PainReform's Remarkable Progress

PainReform Ltd. has made significant strides in its mission to combat the opioid epidemic through the development of PRF-110. This novel drug is a long-lasting formulation of the commonly used anesthetic ropivacaine and holds great promise in offering prolonged pain relief without the risk of addiction associated with opioids.

During the interview, Hadar highlighted the company's commitment to staying ahead of the curve by focusing on innovation and addressing unmet needs in pain management. He emphasized that PainReform aims to provide physicians and patients with a safe and effective alternative to opioids, reducing the risks associated with addiction and abuse.

Understanding the Potential of PRF-110

PRF-110's unique extended-release formulation allows for sustained pain relief, making it an ideal candidate for managing post-operative pain and other chronic pain conditions. Furthermore, the drug's long-lasting effects may potentially reduce the need for opioids during recovery, curbing the risk of opioid dependency and abuse.

Hadar pointed out that PainReform has made significant progress in the development of PRF-110, including successful preclinical and clinical trials. The drug has exhibited positive results in terms of efficacy and safety, with minimal adverse effects reported by patients. Such findings further validate PainReform's commitment to offering a safer alternative to opioids in pain management.

Industry Landscape and PainReform's Competitive Advantage

Within the Major Pharmaceutical Preparations industry, PainReform stands out with its commitment to developing innovative solutions for pain management. Although the company recorded a net loss of $-9 million in the past twelve months, highlighting the challenges they faced, the company's dedication to R&D and its focus on addressing the opioid crisis shine through.

Despite the net loss, PainReform has showcased its determination to make a difference by prioritizing patient safety and well-being. While facing competition from other pharmaceutical companies with higher returns on equity, PainReform's focus on reformulation of established therapeutics and its innovative approach give the company a unique competitive advantage.


PainReform CEO, Ilan Hadar's interview sheds light on the potential impact of PRF-110 in addressing the opioid epidemic. By offering an extended-release formulation of ropivacaine, PainReform aims to provide physicians and patients with an effective and safe alternative to opioids for managing acute and chronic pain.

With promising results from preclinical and clinical trials, PainReform takes a noteworthy step towards revolutionizing pain management. The company's commitment to innovation and patient safety sets them apart in the industry, despite the challenges they face.


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