Aligos Therapeutics Makes Strides in Addressing Unmet Medical Needs in Liver and Viral Diseases

Published / Modified Jul 10 2024
CSIMarket Team / CSIMarket.com

Aligos Therapeutics, a renowned clinical-stage biopharmaceutical company, has recently made significant progress in developing innovative therapeutics to combat chronic hepatitis B (CHB) and metabolic dysfunction-associated steatohepatitis (MASH). This article will outline the key findings from their KOL event, the passing of an influential industry leader, and the initiation of their Phase 2a HERALD study, and assess their impact on the company's future endeavors.

Positive Phase 1b Data for ALG-000184 in CHB Treatment:

Aligos Therapeutics is thrilled to announce the successful outcome of the Phase 1b study for ALG-000184, a potential breakthrough treatment for chronic hepatitis B (CHB). The company hosted a virtual KOL event, featuring the renowned Mark Sulkowski, MD from Johns Hopkins University School of Medicine. This event aimed to shed light on the unmet medical needs in CHB, discuss the positive Phase 1b data, elaborate on development plans, and explore the chronic suppression regulatory pathway.

The positive Phase 1b data signifies a significant milestone for Aligos Therapeutics, positioning them at the forefront of CHB treatment innovation. With the expertise of medical professionals like Dr. Sulkowski, the company is poised to explore novel therapeutic options that could revolutionize the current treatment landscape, ultimately enhancing the lives of CHB patients worldwide.

The Loss of Stephen A. Harrison, MD, an Industry Leader:

Aligos Therapeutics was deeply saddened by the recent passing of Stephen A. Harrison, MD, an esteemed industry leader. Dr. Harrison had served as a trusted advisor and the Principal Investigator for the company's ongoing Phase 2a HERALD study in MASH subjects. His invaluable contributions and insights played a crucial role in the development of innovative therapeutics for metabolic dysfunction-associated steatohepatitis.

While the loss of Dr. Harrison is undoubtedly a significant blow to the industry, his legacy and impact will continue to inspire Aligos Therapeutics. The company remains committed to honoring his memory by carrying forward his vision of addressing unmet medical needs in liver diseases and striving to make a substantial difference in patients' lives.

Initiation of Phase 2a HERALD Study for ALG-055009 in MASH Subjects:

Aligos Therapeutics recently commenced dosing in the Phase 2a HERALD study, focusing on ALG-055009, a potential breakthrough therapy for metabolic dysfunction-associated steatohepatitis (MASH). This study aims to evaluate the safety and efficacy of ALG-055009 in subjects suffering from this debilitating liver disease.

The initiation of the Phase 2a HERALD study marks a significant step forward for Aligos Therapeutics in their pursuit of addressing unmet medical needs. By focusing on the development of novel therapeutics for MASH, the company demonstrates their commitment to combatting liver diseases and enhancing the quality of life for affected individuals.


Aligos Therapeutics continues to achieve remarkable progress in its mission to develop innovative therapeutics for liver and viral diseases. Their positive Phase 1b data for ALG-000184 in CHB treatment, alongside the initiation of the Phase 2a HERALD study for ALG-055009 in MASH subjects, showcases their dedication and significant strides in addressing unmet medical needs. Despite the loss of an influential industry leader, the Company remains resolute in its commitment to making a substantial impact on patient care and treatment outcomes.

Sources for this article: Aligos Therapeutics Inc Press release, News Wire, Globe Newswire, Business wire, Pr newswire.... and CSIMarket.com Customer Analytics Research for Aligos Therapeutics Inc


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