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Denali Therapeutics Inc   (NASDAQ: DNLI)
Other Ticker:  
 
 
Price: $21.9300 $0.26 1.200%
Day's High: $22.265 Week Perf: 11.94 %
Day's Low: $ 21.47 30 Day Perf: -5.84 %
Volume (M): 868 52 Wk High: $ 33.33
Volume (M$): $ 19,037 52 Wk Avg: $22.20
Open: $21.93 52 Wk Low: $14.56



 Market Capitalization (Millions $) 3,716
 Shares Outstanding (Millions) 169
 Employees 445
 Revenues (TTM) (Millions $) -
 Net Income (TTM) (Millions $) -366
 Cash Flow (TTM) (Millions $) -57
 Capital Exp. (TTM) (Millions $) 13

Denali Therapeutics Inc
Denali Therapeutics Inc is a biotechnology company that focuses on discovering and developing treatments for neurodegenerative diseases, such as Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis (ALS), and Huntington's disease.
The company was founded in 2015 by a group of leading scientists and drug developers from Genentech, including Ryan Watts, Alex Schuth, and Marc Tessier-Lavigne.
Denali's approach to drug development is based on the use of proprietary technologies such as the Transport Vehicle platform and the Neuroimmunology platform.
The Transport Vehicle platform is designed to allow large molecules such as antibodies to cross the blood-brain barrier, which is essential for treating neurodegenerative diseases.
The Neuroimmunology platform is focused on developing therapies that modulate the immune system's response to neurodegenerative diseases.
Currently, Denali has several drug candidates in its pipeline that are designed to address the underlying biology of neurodegenerative diseases.
One of the company's lead drug candidates is DNL151, an oral small molecule inhibitor of leucine-rich repeat kinase 2 (LRRK2), which is a genetically validated target for Parkinson's disease.
Denali also has a collaboration with Sanofi to develop potential treatments for multiple sclerosis and other neuroinflammatory disorders.
The company is headquartered in South San Francisco, California, and has over 400 employees, including scientists, researchers, and drug developers with extensive experience in the biotechnology industry.
Denali has received over $600 million in funding from leading investors such as Fidelity, Flagship Pioneering, and the Alaska Permanent Fund Corporation.
Overall, Denali is focused on developing breakthrough therapies that have the potential to improve the lives of patients with neurodegenerative diseases.


   Company Address: 161 Oyster Point Blvd South San Francisco 94080 CA
   Company Phone Number: 866-8548   Stock Exchange / Ticker: NASDAQ DNLI


   

Stock Performances by Major Competitors

5 Days Decrease / Increase
     
AMGN        0.71% 
BIIB   -6.41%    
CHRS   -5.44%    
EXEL        2.55% 
GILD        2.11% 
HALO        1.22% 
• View Complete Report
   



Management Announcement

Denali Therapeutics Charts Ambitious Course for 2025 Amid Financial Challenges and Pivotal FDA Discussions on Hunter Syndrome Therapy,

Published Mon, Jan 13 2025 1:02 PM UTC

Denali Therapeutics Sets Ambitious 2025 Milestones Despite Financial StrugglesDenali Therapeutics Inc., a biotech firm focused on developing therapies for neurodegeneration and lysosomal storage diseases, recently outlined its key anticipated milestones for 2025. The company?s Chief Executive Officer, Ryan Watts, Ph.D., is scheduled to present these goals at the 43rd Annual...

Clinical Study

Denali Therapeutics Moves Forward with Accelerated Approval Plans for Tividenofusp Alfa amid Market Challenges

Published Tue, Sep 3 2024 12:01 PM UTC

Denali Therapeutics Inc. has recently announced a successful meeting with the U.S. Food and Drug Administration (FDA) concerning its investigational therapeutic, Tividenofusp Alfa (DNL310), aimed at treating Mucopolysaccharidosis Type II (MPS II), commonly known as Hunter Syndrome. The meeting was a significant milestone for the company, as it signals a forthcoming applicati...

Clinical Study

The Promising Advancements in Oligonucleotide Transport for Neurological Treatment A Discourse on Denali Therapeutics...

Published Wed, Aug 14 2024 6:00 PM UTC

In the venerable realm of biopharmaceutical innovation, the illustrious Denali Therapeutics Inc., headquartered in the charming enclave of South San Francisco, has recently revealed a monumental stride in medical science, one that reverberates with profound implications for the treatment of neurodegenerative and lysosomal storage maladies. The company, whose endeavours are p...

Denali Therapeutics Inc

Revenue stagnation but improved financial performance for Denali Therapeutics Inc.

Denali Therapeutics Inc., a biopharmaceutical company headquartered in South San Francisco, California, is dedicated to developing innovative treatment options for neurodegenerative diseases and lysosomal storage diseases. The company's main focus is on developing a broad portfolio of product candidates engineered to cross the blood-brain barrier (BBB), an essential component for treating diseases of the central nervous system.
In their most recent financial report for the fiscal interval ending March 31, 2024, Denali Therapeutics Inc. saw a decrease in loss per share, from $-0.80 per share to $-0.68 per share compared to the previous year. Earnings per share also improved from $-0.80 per share in the prior financial reporting period. Despite these positive changes, the company's revenue remained unchanged at $0.00 million from $35.14 million in the corresponding financial reporting period a year ago. However, the company reported a net shortfall of $-101.802 million, an improvement from a deficit of $-109.781 million in the previous year.

Clinical Study

Denali Therapeutics Completes Enrollment for Regimen G in Phase 2/3 HEALEY ALS Platform Trial, Signifying Progress in Neurodegenerative Disease Treatment

Published Wed, May 1 2024 12:01 PM UTC

Denali Therapeutics Inc., a leading biopharmaceutical company committed to developing innovative treatment options for neurodegenerative and lysosomal storage diseases, has announced the successful completion of enrollment for Regimen G in the Phase 2/3 HEALEY ALS Platform Trial. This achievement marks a significant milestone for both Denali Therapeutics and the field of neu...










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