CSIMarket
 
Ionis Pharmaceuticals Inc   (NASDAQ: IONS)
 
Price: $60.6300 $0.27 0.447%
Day's High: $60.9900016784668 Week Perf: -4.31 %
Day's Low: $ 60.27 30 Day Perf: 11.27 %
Volume (M): 125,828 52 Wk High: $ 86.74
Volume (M$): $ 0 52 Wk Avg: $72.41
Open: $60.37 52 Wk Low: $49.13



 Market Capitalization (Millions $) 10,029
 Shares Outstanding (Millions) 165
 Employees 1,402
 Revenues (TTM) (Millions $) 1,169
 Net Income (TTM) (Millions $) -313
 Cash Flow (TTM) (Millions $) -199
 Capital Exp. (TTM) (Millions $) 23

Business Description


Ionis Pharmaceuticals Inc is a biopharmaceutical company that has its headquarters in Carlsbad, California, United States. The company's main focus is on the development of RNA-targeted therapeutics which can help in treating various diseases. The company has been in operation since 1989 and it was formerly known as Isis Pharmaceuticals. It changed its name to Ionis Pharmaceuticals in December 201

Ionis Pharmaceuticals has a unique therapeutic approach that involves the development of antisense drug candidates, which are designed to target RNA molecules in the body. The company has a wide range of research and development programs that are focused on developing drugs for different diseases. Some of these diseases include neurological disorders, cardiovascular diseases, and various types of cancer.

One of the company's most well-known products is Spinraza, which is a drug that treats spinal muscular atrophy (SMA). SMA is a genetic disorder that causes progressive muscle weakness and it is one of the leading causes of infant mortality. Spinraza was approved by the US Food and Drug Administration (FDA) in December 2016, and it is now widely used in the treatment of SMA.

In addition to Spinraza, Ionis Pharmaceuticals has several other drugs in clinical development. These drugs include drugs for the treatment of Huntington's disease, cardiovascular disease, and cancer. The company has also been able to establish several collaborations with other pharmaceutical companies, which has helped to leverage its antisense technology to create more effective drugs.

Ionis Pharmaceuticals has a strong financial position and has been able to raise significant amounts of capital over the years. The company's revenue is mainly generated from royalties, licensing fees, and milestone payments from its partnerships. In 2020, the company generated $192 million in revenue, a significant increase from the previous year.

In conclusion, Ionis Pharmaceuticals Inc is a biopharmaceutical company that has gained recognition for its unique approach to RNA-targeted therapeutics. The company's innovative products have shown promising results in the treatment of various diseases, and with its strong financial position, it is well positioned to continue developing cutting-edge therapies in the future.


   Company Address: 2855 Gazelle Court Zagreb 92010 City of Zagreb
   Company Phone Number: 931-9200   Stock Exchange / Ticker: NASDAQ IONS


   

Stock Performances by Major Competitors

5 Days Decrease / Increase
     
ARWR   -8.71%    
AXSM   -1.38%    
CLNN   -1.13%    
CORT   -7.39%    
PFE        1.24% 
SLN        0.37% 
• View Complete Report
   



Business Update

Ionis Pharmaceuticals Showcases Promising Data on Pioneering Therapies at ACAAI 2025,

Published Fri, Nov 7 2025 2:18 PM UTC

Ionis Pharmaceuticals Unveils Groundbreaking Research Data at ACAAI 2025 Annual Meeting As the biopharmaceutical landscape continues to evolve, Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) recently showcased promising advancements at the 2025 American College of Allergy, Asthma & Immunology (ACAAI) Annual Scientific Meeting held in Orlando, Florida. Among the highlights were s...

Business Update

Ionis Pharmaceuticals Charting New Paths in Biotech Brilliance,

Published Wed, Oct 29 2025 12:17 PM UTC

Pioneering the Future: Ionis Pharmaceuticals’ Strategic Advances and Financial Milestones CARLSBAD, Calif. - In a significant turn of events this past quarter, Ionis Pharmaceuticals Inc. (Nasdaq: IONS) marked a noteworthy inflection point in its history, signaling its fortification in the pharmaceutical landscape with robust financial results and strategic program advancem...

Business Update

Zilganersen Breakthrough Ionis Pharmaceuticals Transforms Hope into Reality for Alexander Disease,

Published Mon, Sep 22 2025 1:56 PM UTC

Unlocking Potential: Ionis Pharmaceuticals Pioneers New Hope for Alexander Disease In the realm of biotechnology, where innovation often dances hand in hand with the promise of transforming lives, Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) has once again risen to the occasion. The company’s recent announcement of positive topline results from its pivotal study of zilganers...

Business Update

Olezarsen Shows Promising Results in Reducing Triglycerides and Pancreatitis Risk Ionis Pharmaceuticals Reports Key A...

Published Tue, Sep 2 2025 1:06 PM UTC

Olezarsen: A Revolutionary Breakthrough in Treating Hypertriglyceridemia by Ionis Pharmaceuticals Hypertriglyceridemia (HTG), characterized by elevated levels of triglycerides in the blood, poses a significant health risk for individuals worldwide. Severe hypertriglyceridemia (sHTG) can lead to acute pancreatitis, a condition that causes inflammation of the pancreas and is a...

Business Update

Pioneering RNA-Targeted Therapy FDA Greenlights DAWNZERA for Hereditary Angioedema,

Published Thu, Aug 21 2025 4:13 PM UTC

U.S. FDA Approves DAWNZERA as First RNA-Targeted Treatment for Hereditary Angioedema In a groundbreaking development for the treatment of hereditary angioedema (HAE), Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) has announced that the U.S. Food and Drug Administration (FDA) has approved DAWNZERA (donidalorsen). This approval marks a significant milestone as DAWNZERA becomes th...




Fundamental Analysis

Valuation Current
Price to Earnings PE Ratio (TTM) -
Price to Earnings PE Ratio (Expected) -
Price to Sales (TTM) 8.58
Price to Sales (Expected) -
Price to Book 22.81
PEG (TTM) -

Financial Strength Current
Quick Ratio 1.11
Working Capital Ratio 1.27
Leverage Ratio (MRQ) 5.81
Total Debt to Equity -
Interest Coverage (TTM) -
Debt Coverage (TTM) -

Per Share Current
Earnings (TTM) -1.98 $
Revenues (TTM) 7.07 $
Cash Flow (TTM) -
Cash 2.12 $
Book Value 2.66 $
Dividend (TTM) 0 $

Efficiency Current
Revenue per Employee (TTM) 834,108
Net Income per Employee (TTM) -223,265
Receivable Turnover Ratio (TTM) -
Inventory Turnover Ratio (TTM) 0.53
Asset Turnover Ratio (TTM) 0.36

Profitability Ratios Current
Gross Margin (MRQ) 98.98 %
Operating Margin (MRQ) -38.18 %
Net Margin (MRQ) -42.79 %
Net Cash Flow Margin (MRQ) 0 %
Effective Tax Rate (TTM) -

Management Effectiveness Current
Return On Assets (TTM) -
Return On Investment (TTM) -
Return On Equity (TTM) -
Dividend Yield -
Pay out Ratio (TTM) -



Ionis Pharmaceuticals Inc's Segments
Product    27.65 % of total Revenue
Royalty    50.11 % of total Revenue
WAINUA Joint Development Revenue    12.62 % of total Revenue
Commercial    84.51 % of total Revenue
Collaborative Agreement Revenue    94.72 % of total Revenue
Research and Development Revenue    107.34 % of total Revenue
Tryngolza    11.82 % of total Revenue
DAWNZERA Sales    15.83 % of total Revenue
SPINRAZA Royalties    36.27 % of total Revenue
TRYNGOLZA Sales    10.13 % of total Revenue
Other Royalties    3.71 % of total Revenue
Salanersen    16.79 % of total Revenue
Otsuka    7.46 % of total Revenue
Zilganersen    7.84 % of total Revenue
Ionis Operations    191.84 % of total Revenue





Help

About us

Products

Data downloads

API

CSIMarket Company, Sector, Industry, Market Analysis, Stock Quotes, Earnings, Economy, News and Research.

Intraday data delayed per exchange requirements. All quotes are in local exchange time. Intraday data delayed 15 minutes for Nasdaq, and other exchanges. Fundamental and financial data for Stocks, Sector, Industry, and Economic Indicators provided by CSIMarket.com

Disclaimer: Information provided by CSIMarket.com is for informational purposes only and does not constitute investment advice, recommendation, or solicitation to buy or sell any security.

© 2026 CSIMarket.com — Proprietary financial dataset. All rights reserved. Redistribution or automated extraction prohibited.