Ionis Pharmaceuticals Inc 's ROE per quarter

Return on Equity, Quarterly Results, Trends, Rankings, Statistics

What is ROE for Ionis Pharmaceuticals Inc in the second quarter 2026?
Ionis Pharmaceuticals Inc recorded a cumulative net loss of $-313 million during 12 months ending in the second quarter 2026, resulting in a negative return on equity (ROE) of -61.02%.

Within the Major Pharmaceutical Preparations industry 196 other companies had a higher return on equity. While return on equity, the total ranking has deteriorated compared to the first quarter 2026 from 3285 to 3286.

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Return On Equity	(Jun 30 2026) II. Quarter	(Mar 31 2026) I. Quarter	(Dec 31 2025) IV. Quarter	(Jun 30 2025) II. Quarter	(Mar 31 2025) I. Quarter
Y / Y Equity Change	-7.57 %	-18.1 %	-26.17 %	139.56 %	-
Y / Y Net Income Change	-	-	-	-	-
Net Income (TTM) in Millions	-313	-345	-357	-268	-458
Return On Equity (TTM)	-61.02 %	-66.15 %	-65.04 %	-45.27 %	-91.52 %
IONS's Total Ranking	# 3286	# 3285	# 0	# 0	#
Equity (TTM) in Millions	440	491	489	632	476
Seq. Equity Change	-10.52 %	0.48 %	-22.58 %	32.79 %	-20.71 %
Seq. Net Income Change	-	-	-	-	-

Back to IONS Management Effectiveness >> IONS's 5 Years Annual ROE >> Compare IONS ROE to its Competitors

Return On Equity Company Ranking
Within:	No.
Industry	# 197
Sector	# 455
Overall	# 3286

Return On Equity Statistics
High	Average	Low
29.93 %	-29.67 %	-126.88 %
(Mar 31 2019)		(Jun 30 2016)

IONS Annual Return On Equity	(Sep 30 2025) 2025	(Dec 31 2024) 2024	(Dec 31 2023) 2023	(Dec 31 2022) 2022	(Dec 31 2021) 2021
Total Equity in Millions	618	600	387	573	772
Y / Y Equity Change	2.99 %	55.16 %	-32.5 %	-25.77 %	-8.49 %
Net Income in Millions	-129	-454	-366	-270	-29
Y / Y Net Income Change	-	-	-	-	-
Return On Equity	-20.81 %	-75.65 %	-94.72 %	-47.08 %	-3.71 %

Back to IONS Management Effectiveness >> IONS's 5 Years Annual ROE >> Compare IONS ROE to its Competitors

More Return On Equity Ratios
Major Pharmaceutical Preparations Industry Roe Trends and Statistics
Healthcare Sector Return On Equity Statistics
IONS's' Return on Equity at Yahoo Finance
IONS's Roe Ratio versus Major Pharmaceutical Preparations Industry, Healthcare Sector and overall Market
Highest Ranking Return On Equity
Lowest Ranking Return On Equity
Subscribers only: Roe for IONS's Competitors
Subscribers only: Roe for Ionis Pharmaceuticals Inc 's Suppliers
Subscribers only: Return On Equity for IONS's Customers

Companies with similar Return On Equity at Jun 30 2026, within Healthcare Sector

ROE

Date modified: 2026-08-13T08:57:28+00:00

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