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Stoke Therapeutics Inc   (NASDAQ: STOK)
 
Price: $29.8100 $-0.18 -0.600%
Day's High: $30.027999877929688 Week Perf: -4.46 %
Day's Low: $ 29.15 30 Day Perf: -6.64 %
Volume (M): 714,000 52 Wk High: $ 40.22
Volume (M$): $ 0 52 Wk Avg: $30.99
Open: $29.41 52 Wk Low: $20.32



 Market Capitalization (Millions $) 1,880
 Shares Outstanding (Millions) 63
 Employees 170
 Revenues (TTM) (Millions $) 32
 Net Income (TTM) (Millions $) -170
 Cash Flow (TTM) (Millions $) -116
 Capital Exp. (TTM) (Millions $) 1

Business Description


Stoke Therapeutics Inc. is a biotechnology company that is focused on developing innovative therapies for patients with severe genetic diseases, particularly diseases caused by haploinsufficiency. Haploinsufficiency is a genetic condition where a person has only one functioning copy of a gene instead of the normal two, leading to a reduced expression of the gene and potentially causing disease.

Stoke Therapeutics is leveraging its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) platform to address this issue. The TANGO platform utilizes antisense oligonucleotides to enhance the expression of the non-mutated copy of the gene, increasing the production of the specific protein and potentially treating the underlying disease.

The company aims to develop therapies for a range of genetic disorders, including genetic epilepsies, neurodevelopmental disorders, and other diseases that are not adequately addressed by current treatment options. Stoke Therapeutics is conducting clinical trials and partnering with academic institutions and industry collaborators to accelerate the development and commercialization of its therapies.

Overall, Stoke Therapeutics is at the forefront of developing innovative treatments for severe genetic diseases, using its TANGO platform to enhance gene expression and offer potential therapeutic options for patients in need.


   Company Address: 45 Wiggins Ave Bedford 1730 MA
   Company Phone Number: 430-8200   Stock Exchange / Ticker: NASDAQ STOK


   

Stock Performances by Major Competitors

5 Days Decrease / Increase
     
ALNY        12.24% 
ARWR        1.68% 
PTCT   -1.13%    
REGN        4.22% 
SRPT        7.86% 
UTHR   -5.4%    
• View Complete Report
   



Business Update

Stoke Therapeutics Catalyzing Innovation with RNA Medicines Amid Financial and Strategic Milestones,

Published Wed, Nov 5 2025 10:20 AM UTC

Stoke Therapeutics, Inc., a Nasdaq-listed biotechnology innovator, continues to make significant strides in RNA medicine with its lead investigational therapy, zorevunersen, aimed at modifying diseases such as Dravet syndrome. In recent updates, the company has reported financial results for both the third quarter of 2025 and the full year of 2024, alongside strategic partic...

Business Update

Innovations in RNA Medicine Stoke Therapeutics Highlights Path Forward in Dravet Syndrome at the Needham Conference

Published Wed, Apr 2 2025 9:44 AM UTC

Stoke Therapeutics Showcases Groundbreaking Approach to RNA Medicine at 24th Annual Needham Virtual Healthcare Conference In an exciting development for the field of biotechnology, Stoke Therapeutics, Inc. (Nasdaq: STOK) is set to present at the 24th Annual Needham Virtual Healthcare Conference. The company, headquartered in Bedford, Massachusetts, is making waves in the pha...

Business Update

Stoke Therapeutics Pioneering New Frontiers in RNA Medicine for Dravet Syndrome

Published Thu, Feb 27 2025 9:26 AM UTC

Stoke Therapeutics, Inc. (Nasdaq: STOK), based in Bedford, Massachusetts, is making noteworthy strides in the biotechnology sector with its pioneering approach to RNA medicine. Focused on restoring protein expression, Stoke Therapeutics is positioning itself as a leader in innovative therapeutics aimed at addressing genetic disorders. Recent announcements regarding upcoming ...

Business Update

Stoke Therapeutics Zorevunersen A Beacon of Hope Amidst Competitive Challenges

Published Fri, Dec 6 2024 7:47 PM UTC

The landscape of pharmaceutical innovation is continually evolving, especially for complex neurological disorders like Dravet Syndrome. At the forefront of this battle is Stoke Therapeutics, Inc. (Nasdaq: STOK), a company committed to leveraging RNA medicine to revive protein expression. Recent findings from their open-label extension (OLE) study spotlight the promising pote...

Business Update

Stoke Therapeutics Unveils Promising Zorevunersen Data as Potential Game-Changer for Dravet Syndrome Treatment,

Published Sat, Dec 7 2024 6:52 AM UTC

Stoke Therapeutics, Inc. a pioneering biotechnology company listed on Nasdaq under the symbol STOK, continues to make significant strides in the battle against Dravet syndrome a severe and often debilitating form of epilepsy. Employing its proprietary RNA medicine approach, Stoke Therapeutics focuses on harnessing the body’s intrinsic potential to restore protein expressio...




Fundamental Analysis

Valuation Current
Price to Earnings PE Ratio (TTM) -
Price to Earnings PE Ratio (Expected) -
Price to Sales (TTM) 58.60
Price to Sales (Expected) -
Price to Book 4.76
PEG (TTM) -

Financial Strength Current
Quick Ratio 20.32
Working Capital Ratio 21.69
Leverage Ratio (MRQ) 0.12
Total Debt to Equity -
Interest Coverage (TTM) -
Debt Coverage (TTM) -

Per Share Current
Earnings (TTM) -2.82 $
Revenues (TTM) 0.51 $
Cash Flow (TTM) -
Cash 5.45 $
Book Value 6.26 $
Dividend (TTM) 0 $

Efficiency Current
Revenue per Employee (TTM) 188,706
Net Income per Employee (TTM) -998,629
Receivable Turnover Ratio (TTM) 6.54
Inventory Turnover Ratio (TTM) -
Asset Turnover Ratio (TTM) 0.08

Profitability Ratios Current
Gross Margin (MRQ) -
Operating Margin (MRQ) -857.57 %
Net Margin (MRQ) -802.75 %
Net Cash Flow Margin (MRQ) 1195.04 %
Effective Tax Rate (TTM) -

Management Effectiveness Current
Return On Assets (TTM) -
Return On Investment (TTM) -
Return On Equity (TTM) -
Dividend Yield -
Pay out Ratio (TTM) -



Stoke Therapeutics Inc's Segments
Global Development Activity    64.75 % of total Revenue





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