The company sources raw materials, active pharmaceutical ingredients (APIs), and finished products for denifanstat, TVB-3567, and resmetirom from multiple suppliers and contract manufacturing organizations (CMOs). Four CMOs located in Europe, the United States, and China, along with their license partner Ascletis, produce drug substances. For drug products, the company utilizes two CMOs in the United States and China, as well as Ascletis. In December 2025, the company entered into a license agreement with Assia Chemical Industries Ltd., operating as TAPI Technology & API Services (TAPI), a subsidiary of Teva Pharmaceutical Industries Ltd., granting TAPI a global, exclusive license to certain intellectual property rights related to resmetirom API for evaluation and potential further development. All CMOs operate under current Good Manufacturing Practice (cGMP) requirements and applicable laws and regulations.
Sagimet Biosciences Inc's Comment on Supply Chain
The company sources raw materials, active pharmaceutical ingredients (APIs), and finished products for denifanstat, TVB-3567, and resmetirom from multiple suppliers and contract manufacturing organizations (CMOs). Four CMOs located in Europe, the United States, and China, along with their license partner Ascletis, produce drug substances. For drug products, the company utilizes two CMOs in the United States and China, as well as Ascletis. In December 2025, the company entered into a license agreement with Assia Chemical Industries Ltd., operating as TAPI Technology & API Services (TAPI), a subsidiary of Teva Pharmaceutical Industries Ltd., granting TAPI a global, exclusive license to certain intellectual property rights related to resmetirom API for evaluation and potential further development. All CMOs operate under current Good Manufacturing Practice (cGMP) requirements and applicable laws and regulations.
Sources:
Sagimet Biosciences inc 's official press releases and regulatory filings; CSIMarket.com's supply-chain research; and the financial filings and press releases of other companies cited in this report.
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