Soleno Therapeutics Inc (SLNO) Return on Equity ROE from the first quarter 2026 to first quarter 2025 and annually, average high and low, overall ranking from Mar 31 2026 to Mar 31 2025 - CSIMarket
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Soleno Therapeutics Inc  (NASDAQ: SLNO)

Soleno Therapeutics Inc's ROE per quarter

Return on Equity, Quarterly Results, Trends, Rankings, Statistics


What is ROE for Soleno Therapeutics Inc in the first quarter 2026?
Soleno Therapeutics Inc achieved a return on average equity (ROE) of 22.85 % in its first quarter 2026 a new company high.

While the company's net income was fading, Soleno Therapeutics Inc was able to improve its ROE compared to the fourth quarter 2025.

Within the Medical Equipment & Supplies industry 11 other companies had a higher return on equity. While Return on equity, overall ranking has advanced in the quarter, so far to 587, from total ROE ranking in the fourth quarter 2025 at 1362.

What is ROE?




Return On Equity (Mar 31 2026)
I. Quarter
(Dec 31 2025)
IV. Quarter
(Sep 30 2025)
III. Quarter
(Jun 30 2025)
II. Quarter
(Mar 31 2025)
I. Quarter
Y / Y Equity Change 113.47 % 83.64 % 86.93 % -14.47 % -
Y / Y Net Income Change - - - - -
Net Income (TTM) in Millions 96 21 -78 -181 -198
Return On Equity (TTM) 22.85 % 5.9 % -25.88 % -73.74 % -77.52 %
SLNO's Total Ranking # 587 # 1362 # 2151 # 2996 # 3110
Equity (TTM) in Millions 496 450 495 240 232
Seq. Equity Change 10.15 % -9.03 % 106.05 % 3.39 % -5.24 %
Seq. Net Income Change -27.63 % 66.68 % - - -

Return On Equity Company Ranking
Within: No.
Industry # 12
Sector # 73
Overall # 587

Return On Equity Statistics
High Average Low
22.85 %
-652.83 %
-22095.81 %
(Mar 31 2026)   (Mar 31 2016)



  News about Soleno Therapeutics Inc Return on Equity ROE

Soleno Therapeutics: Battling Financial Woes, a New Face Takes the Lead,

Soleno Therapeutics Public Offering Raises Questions Amidst Financial Struggles
Soleno Therapeutics, a leading clinical-stage biopharmaceutical company focused on rare disease therapeutics, has recently undergone significant changes in its leadership and financial landscape. The resignation of Ernest Mario, Ph.D., as the Chair of the Board of Directors due to health reasons, and the appointment of Matthew Pauls, J.D., M.B.A., as the new Lead Independent Director, has sparked curiosity among investors and industry insiders. These developments coincide with Soleno Therapeutics recent announcement of its underwritten public offering, which aims to bolster the company s financial position.
However, the timing of these changes and the public offering raises questions about Soleno Therapeutics overall stability and potential for success. The firm has recorded a staggering cumulative net loss of $-33 million during the 12 months ending in the third quarter of 2023. This alarming figure has resulted in a negative return on equity (ROE) of -272.88%, fueling concerns about the company s ability to generate profits and sustain shareholders confidence.

Soleno Therapeutics Submits New Drug Application for DCCR Tablets to Revolutionize Prader-Willi Syndrome Treatment

Soleno Therapeutics Submits New Drug Application for DCCR Tablets to Treat Prader-Willi Syndrome
The pharmaceutical industry is constantly striving to develop innovative treatments for rare diseases, and Soleno Therapeutics is one company at the forefront of this mission. Soleno Therapeutics, a clinical-stage biopharmaceutical company, recently announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the approval of DCCR (diazoxide choline) extended-release tablets. This novel treatment is intended specifically for individuals aged four years and older who suffer from Prader-Willi syndrome (PWS) and experience hyperphagia, a condition that causes excessive hunger and uncontrolled eating.
Prader-Willi syndrome is a complex genetic disorder that affects one in every 15,000 births worldwide. People with PWS face numerous physical, intellectual, and behavioral challenges that require proper management. Currently, there are limited treatment options available, making Soleno Therapeutics submission of the NDA a significant milestone in addressing this unmet medical need.

Soleno Therapeutics Strengthens its Leadership Team to Drive Commercial Success and Global Expansion



Soleno Therapeutics, a clinical-stage biopharmaceutical company specializing in developing innovative therapeutics for rare diseases, has recently made significant appointments to its leadership team. These strategic additions, along with the engagement of esteemed advisors, reflect the company s commitment to enhancing its commercial operations, expanding into European markets, and optimizing its human resources. With these new developments, Soleno Therapeutics aims to propel its growth trajectory and deliver novel treatments to patients in need.
Appointments to the Leadership Team:
Soleno Therapeutics has appointed Meredith Manning, M.B.A., as its Chief Commercial Officer, leveraging her extensive industry experience and expertise to drive commercial success. Manning s strategic guidance and leadership will be instrumental in advancing Soleno s pipeline and maximizing market potential. Additionally, Dairine Dempsey, Ph.D., has been appointed as the Vice President for Europe, charting the company s expansion into European markets. Lauren Budesheim, M.S., has also joined Soleno as the Vice President of Human Resources, responsible for nurturing a talented and driven workforce to support the company s growth aspirations.




SLNO Annual Return On Equity (Dec 31 2025)
2025
(Dec 31 2024)
2024
(Dec 31 2023)
2023
(Dec 31 2022)
2022
(Dec 31 2021)
2021
Total Equity in Millions 450 245 158 10 18
Y / Y Equity Change 83.64 % 55.62 % 1422.1 % -41.84 % -60.93 %
Net Income in Millions 20 -176 -39 -24 -31
Y / Y Net Income Change - - - - -
Return On Equity 4.55 % -71.74 % -24.75 % -232.58 % -173.72 %





Annual Roe Comment
In 2025 ROE improved to 4.55 % compared to the previous year, due to net income growth.


More Return On Equity Ratios
Medical Equipment & Supplies Industry Roe Trends and Statistics
Healthcare Sector Return On Equity Statistics
SLNO's' Return on Equity at Yahoo Finance
SLNO's Roe Ratio versus Medical Equipment & Supplies Industry, Healthcare Sector and overall Market
Highest Ranking Return On Equity
Lowest Ranking Return On Equity
Subscribers only: Roe for SLNO's Competitors
Subscribers only: Roe for Soleno Therapeutics Inc's Suppliers
Subscribers only: Return On Equity for SLNO's Customers




Companies with similar Return On Equity at Mar 31 2026, within Healthcare Sector ROE
Zoetis Inc   61.63 %
Vaxart Inc   61.43 %
Dariohealth Corp   60.52 %
Nrc Health  57.25 %
Oramed Pharmaceuticals Inc  55.40 %
Innoviva Inc   47.59 %
Concentra Group Holdings Parent Inc   46.95 %
Liquidia Corporation  46.82 %
Agilent Technologies inc   44.45 %
Tenet Healthcare Corp  44.20 %
Theravance Biopharma inc   43.85 %
Gilead Sciences Inc   42.33 %
Transmedics Group Inc   41.92 %
Abeona Therapeutics Inc   41.40 %
Apellis Pharmaceuticals Inc   39.71 %
Adma Biologics Inc   38.97 %
Bristol myers Squibb Company  38.94 %
Acadia Pharmaceuticals Inc   35.65 %
Spero Therapeutics Inc   35.58 %
Illumina Inc   33.99 %
Dexcom Inc   33.83 %
Rafael Holdings Inc  31.93 %
Solventum Corporation  30.71 %
Phibro Animal Health Corporation  30.60 %
Pro dex Inc   30.01 %
Incyte Corporation  29.20 %
Protalix Biotherapeutics inc   28.10 %
Collegium Pharmaceutical Inc   26.74 %
Pacs Group Inc   26.46 %
Johnson and Johnson  26.26 %


Date modified: 2026-09-12T06:14:45+00:00



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