Prime Medicine Inc (PRME) Return on Investment ROI from the second quarter of 2026 to second quarter of 2025 and for the year 2026, average high and low, overall ranking from Jun 30 2026 to Jun 30 2025 - CSIMarket
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Prime Medicine Inc   (NASDAQ: PRME)


Prime Medicine Inc's ROI from its second quarter of 2026 to the second quarter of 2025 and 5 Year Period

Return on Investment, Quarterly Results, Trends, Rankings, Statistics

What is Prime Medicine Inc's ROI in the second quarter of 2026?
Prime Medicine Inc recorded a cumulative net loss of $-83 million during 12 months ending in the second quarter of 2026, resulting in a negative return on investment (ROI) of -29.5%.

Within the Healthcare sector 363 other companies had a higher return on investment. While return on investment, the total ranking has deteriorated compared to the first quarter of 2026 from 2189 to 3749.

Definition and Formula of Return on Investment



Return On Investment (Jun 30 2026)
II. Quarter
(Mar 31 2026)
I. Quarter
(Dec 31 2025)
IV. Quarter
(Sep 30 2025)
III. Quarter
(Jun 30 2025)
II. Quarter
Y / Y Investment Change TTM 3.46 % 6.56 % 10.52 % 19.84 % 26.66 %
Y / Y Net Income Change TTM - - - - -
Investment (TTM) in Millions 217 258 305 350 245
Return On Investment (TTM) -29.5 % -50.57 % -67.38 % -190.29 % -219.8 %
PRME's Overall Ranking # 3749 # 2189 # 2823 # 3594 # 2879
Seq. Investment Change TTM -2.38 % -2.97 % 3.98 % 5.04 % 0.55 %
Seq. Net Income Change TTM - - - - -
Net Income (TTM) in Millions -83 -146 -201 -546 -601




Return On Investment PRME's Ranking
Within: No.
Industry # 40
Sector # 364
Overall # 3749

Return On Investment Statistics
High Average Low
0.13 %
-64.82 %
-219.8 %
(Dec 31 2023)   (Jun 30 2025)







Financial Statements
Prime Medicine Inc's II. Quarter Investments $ 217 Millions PRME's Balance sheet
Prime Medicine Inc's II. Quarter Income $ -42 Millions Quarterly PRME's Income Statement
PRME's Income by Division See PRME's Income by Division


PRME Annual Return On Investment (Dec 31 2025)
2025
(Dec 31 2024)
2024
(Dec 31 2023)
2023
(Dec 31 2020)
2022

Total Investments in Millions 305 260 137 581 0
Y / Y Investment Growth 17.62 % 88.86 % -76.36 % - -
Net Income in Millions -201 -392 0 -3 0
Y / Y Net Income Growth - - - - -
Annual Return On Investment -65.89 % -150.94 % 0.2 % -0.59 % -


Annual Roi Comment


Definition and Formula of Return on Investment

Other ROI Ratios
Biotechnology & Pharmaceuticals Industry Roi Trends and Statistics
Healthcare Sector Return On Investment Statistics
Roi Trends for overall market
PRME's Roi Ratio versus Biotechnology & Pharmaceuticals Industry, Healthcare Sector and total Market
Highest Ranking Return On Investment
Lowest Ranking Return On Investment
Subscribers only: Roi for PRME's Competitors
Subscribers only: Roi for Prime Medicine Inc's Suppliers
Subscribers only: Return On Investment for PRME's Customers

Other Ratios
PRME's Roa PRME's Inventory Turnover Ratio PRME's Growth Rates PRME's Dividend Statistics
PRME's Profitability Ratios PRME's Asset Turnover Ratio PRME's Dividend Growth
PRME's Roe PRME's Valuation Ratios PRME's Financial Strength Ratios PRME's Dividend Payout Ratio



Companies with similar Return On Investment at Jun 30 2026, within Healthcare Sector ROI


Date modified: 2026-09-26T07:42:02+00:00



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