The registrant utilizes contract manufacturers on a purchase-order basis without long-term supply agreements for bulk drug substances or drug products. The Pharmaceutical Companies intend to identify and qualify additional manufacturers for active pharmaceutical ingredients, formulation, fill-and-finish, labeling, and packaging. The lead product candidate, Trappsol® Cyclo™, is produced through a validated, commercial-scale process by contract manufacturing service providers. LipoMedix acquires bulk drug substances and drug products from established contract manufacturers on a purchase-order basis without long-term or commercial supply arrangements. Rafael Medical Devices maintains relationships with top-tier manufacturers on an as-needed basis but does not own or operate manufacturing, labeling, or packaging facilities. Cornerstone holds manufacturing rights to its lead compound CPI-613® (devimistat) and employs contract manufacturing service providers for production. Named suppliers include Barer, Cornerstone, Cyclo, Day Three, Day Three Labs Manufacturing, LipoMedix, Pharmaceutical Investment Companies, Rafael Medical Devices, and Rafael Pharmaceuticals.
Rafael Holdings Inc's Comment on Supply Chain
The registrant utilizes contract manufacturers on a purchase-order basis without long-term supply agreements for bulk drug substances or drug products. The Pharmaceutical Companies intend to identify and qualify additional manufacturers for active pharmaceutical ingredients, formulation, fill-and-finish, labeling, and packaging. The lead product candidate, Trappsol® Cyclo™, is produced through a validated, commercial-scale process by contract manufacturing service providers. LipoMedix acquires bulk drug substances and drug products from established contract manufacturers on a purchase-order basis without long-term or commercial supply arrangements. Rafael Medical Devices maintains relationships with top-tier manufacturers on an as-needed basis but does not own or operate manufacturing, labeling, or packaging facilities. Cornerstone holds manufacturing rights to its lead compound CPI-613® (devimistat) and employs contract manufacturing service providers for production. Named suppliers include Barer, Cornerstone, Cyclo, Day Three, Day Three Labs Manufacturing, LipoMedix, Pharmaceutical Investment Companies, Rafael Medical Devices, and Rafael Pharmaceuticals.
Sources:
Rafael Holdings Inc's official press releases and regulatory filings; CSIMarket.com's supply-chain research; and the financial filings and press releases of other companies cited in this report.
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