Personalis Inc (PSNL) Return on Investment ROI from the second quarter of 2026 to second quarter of 2025 and for the year 2026, average high and low, overall ranking from Jun 30 2026 to Jun 30 2025 - CSIMarket
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Personalis Inc   (NASDAQ: PSNL)
    Sector • Healthcare    Industry • Medical Laboratories
   Industry • Medical Laboratories
   Sector • Healthcare


Personalis Inc's ROI from its second quarter of 2026 to the second quarter of 2025 and 5 Year Period

Return on Investment, Quarterly Results, Trends, Rankings, Statistics

What is Personalis Inc's ROI in the second quarter of 2026?
Personalis Inc recorded a cumulative net loss of $-107 million during 12 months ending in the second quarter of 2026, resulting in a negative return on investment (ROI) of -40.7%.

Within the Healthcare sector 426 other companies had a higher return on investment. While return on investment, the total ranking has deteriorated compared to the first quarter of 2026 from 3289 to 3611.

Definition and Formula of Return on Investment



Return On Investment (Jun 30 2026)
II. Quarter
(Mar 31 2026)
I. Quarter
(Dec 31 2025)
IV. Quarter
(Sep 30 2025)
III. Quarter
(Jun 30 2025)
II. Quarter
Y / Y Investment Change TTM 15.37 % 21.15 % 28.2 % 31.52 % 32.84 %
Y / Y Net Income Change TTM - - - - -
Investment (TTM) in Millions 266 286 295 207 227
Return On Investment (TTM) -40.7 % -37.67 % -33.46 % -32.26 % -40.01 %
PSNL's Overall Ranking # 3611 # 3289 # 3188 # 3117 # 2956
Seq. Investment Change TTM 3.82 % 4.42 % 6.05 % 0.35 % 9.03 %
Seq. Net Income Change TTM - - - - -
Net Income (TTM) in Millions -107 -96 -81 -74 -91




Return On Investment PSNL's Ranking
Within: No.
Industry # 24
Sector # 427
Overall # 3611

Return On Investment Statistics
High Average Low
-17.33 %
-33.95 %
-52.51 %
(Jun 30 2019)   (Sep 30 2024)



  News about Personalis Inc Return on Investment ROI

Innovating from Within Personalis Strives for Growth in Cancer MRD Testing Amidst Financial Adversities,

September 16, 2024

Advancements in Cancer Monitoring: Evaluating Personalis Inc. Amid Financial ChallengesThe landscape of cancer diagnostics and monitoring continues to evolve, with innovative technologies playing a pivotal role in early detection and patient management. Recent developments from Personalis, Inc. (Nasdaq: PSNL) showcase both promising advancements in cancer care and the financial hurdles the company faces. At the recent European Society of Medical Oncology (ESMO) Congress 2024 in Barcelona, Spain, Personalis presented new data on its NeXT Personal minimal residual disease (MRD) test, a cutting-edge assay aimed at identifying and tracking recurrence in cancer patients through the detection of circulating tumor DNA (ctDNA) in blood samples. Breakthrough in MRD TestingLaunched in late 2023, the NeXT Personal assay has garnered attention for its potential to revolutionize the monitoring of cancer patients. MRD testing is crucial as it provides insights into the effectiveness of treatment and the likelihood of cancer recurrence. By identifying even the smallest traces of ctDNA, the NeXT Personal test promises to enhance the personalization of care, leading to better patient outcomes. Given the increasing importance of targeted therapies and personalized medicine, the role of assays that accurately measure MRD cannot be overstated.

Pioneering Progress in Cancer Care Personalis and Tempus Join Forces for Ultra-Sensitive MRD Testing

August 19, 2024

In a significant development for cancer diagnostics, biotech companies Personalis, Inc. and Tempus AI, Inc. have expanded their collaboration to bring ultra-sensitive minimal residual disease (MRD) testing to market. This announcement, made in November 2023, was officially marked by a launch at the American Society of Clinical Oncology (ASCO) meeting earlier this month, highlighting a promising step forward in the quest for more precise cancer treatment options. A Strategic Alliance for Better Cancer OutcomesPersonalis, based in Fremont, California, is renowned for its sophisticated genomic sequencing and analytics technologies aimed at tailoring immuno-oncology therapies. Tempus, famously recognized for its data-driven precision medicine approach, is leveraging its capabilities to act as the exclusive commercial partner for Personalis’ ultra-sensitive tumor-informed MRD testing product. This partnership is poised to make significant waves in oncology, particularly for breast and lung cancer patients.

Precision Cancer Diagnostics Personalis and Tempus Forge Strategic Alliance to Enhance MRD Testing

August 18, 2024

In a significant advancement within the oncology landscape, Personalis, Inc. (Nasdaq: PSNL) and Tempus AI, Inc. (Nasdaq: TEM) have announced an expanded collaboration aimed at commercializing ultra-sensitive minimal residual disease (MRD) testing. This partnership, officially disclosed in November 2023, aims to bring enhanced diagnostic capabilities to the medical community, specifically targeting breast and lung cancers.The collaboration emerged in the wake of increased demand for precise and reliable cancer monitoring solutions. Personalis, a leader in genomics and personalized medicine, has developed an ultra-sensitive tumor-informed MRD testing product designed to detect residual cancer cells following treatment. This testing methodology is pivotal, as its high sensitivity can significantly improve patient outcomes by enabling clinicians to make informed decisions regarding ongoing treatment strategies.






Financial Statements
Personalis Inc's II. Quarter Investments $ 266 Millions PSNL's Balance sheet
Personalis Inc's II. Quarter Income $ -32 Millions Quarterly PSNL's Income Statement
PSNL's Income by Division See PSNL's Income by Division


PSNL Annual Return On Investment (Dec 31 2025)
2025
(Dec 31 2024)
2024
(Dec 31 2023)
2023
(Dec 31 2022)
2022
(Dec 31 2021)
2021
Total Investments in Millions 295 239 178 260 365
Y / Y Investment Growth 23.16 % 34.45 % -31.48 % -28.93 % 78.85 %
Net Income in Millions -81 -81 -108 -113 -65
Y / Y Net Income Growth - - - - -
Annual Return On Investment -27.59 % -33.99 % -60.89 % -43.66 % -17.86 %


Annual Roi Comment


Definition and Formula of Return on Investment

Other ROI Ratios
Medical Laboratories Industry Roi Trends and Statistics
Healthcare Sector Return On Investment Statistics
Roi Trends for overall market
PSNL's Roi Ratio versus Medical Laboratories Industry, Healthcare Sector and total Market
Highest Ranking Return On Investment
Lowest Ranking Return On Investment
Subscribers only: Roi for PSNL's Competitors
Subscribers only: Roi for Personalis Inc's Suppliers
Subscribers only: Return On Investment for PSNL's Customers

Other Ratios
PSNL's Roa PSNL's Inventory Turnover Ratio PSNL's Growth Rates PSNL's Dividend Statistics
PSNL's Profitability Ratios PSNL's Asset Turnover Ratio PSNL's Dividend Growth
PSNL's Roe PSNL's Valuation Ratios PSNL's Financial Strength Ratios PSNL's Dividend Payout Ratio



Companies with similar Return On Investment at Jun 30 2026, within Healthcare Sector ROI


Date modified: 2026-09-26T07:36:44+00:00



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