Prelude Therapeutics Inc (PRLD) Return on Investment ROI from the second quarter of 2026 to second quarter of 2025 and for the year 2026, average high and low, overall ranking from Jun 30 2026 to Jun 30 2025 - CSIMarket
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Prelude Therapeutics Inc  (NASDAQ: PRLD)


Prelude Therapeutics Inc's ROI from its second quarter of 2026 to the second quarter of 2025 and 5 Year Period

Return on Investment, Quarterly Results, Trends, Rankings, Statistics

What is Prelude Therapeutics Inc's ROI in the second quarter of 2026?
Prelude Therapeutics Inc recorded a cumulative net loss of $-60 million during 12 months ending in the second quarter of 2026, resulting in a negative return on investment (ROI) of -60.13%.

Within the Healthcare sector 521 other companies had a higher return on investment. While return on investment, the total ranking has deteriorated compared to the first quarter of 2026 from 2871 to 4006.

Definition and Formula of Return on Investment


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Return On Investment (Jun 30 2026)
II. Quarter		 (Mar 31 2026)
I. Quarter		 (Dec 31 2025)
IV. Quarter		 (Sep 30 2025)
III. Quarter		 (Jun 30 2025)
II. Quarter
Y / Y Investment Change TTM -25.91 % -46.28 % -48.56 % -48.06 % -41.47 %
Y / Y Net Income Change TTM - - - - -
Investment (TTM) in Millions 151 81 91 79 97
Return On Investment (TTM) -60.13 % -89.48 % -102.43 % -99.94 % -91.57 %
PRLD's Overall Ranking # 4006 # 2871 # 3168 # 3674 # 3282
Seq. Investment Change TTM 15.7 % -10.5 % -13.15 % -17.62 % -16.1 %
Seq. Net Income Change TTM - - - - -
Net Income (TTM) in Millions -60 -78 -99 -112 -124

PRLD Company Profile >> Back to PRLD Roi Comparisons >> See Annual PRLD Return On Investment



Return On Investment PRLD's Ranking
Within: No.
Industry # 226
Sector # 522
Overall # 4006

Return On Investment Statistics
High Average Low
-29.75 %
-57.88 %
-102.43 %
(Jun 30 2021)   (Dec 31 2025)







Financial Statements
Prelude Therapeutics Inc's II. Quarter Investments $ 151 Millions PRLD's Balance sheet
Prelude Therapeutics Inc's II. Quarter Income $ -14 Millions Quarterly PRLD's Income Statement
PRLD's Income by Division See PRLD's Income by Division


PRLD Annual Return On Investment (Dec 31 2025)
2025		 (Dec 31 2024)
2024		 (Dec 31 2023)
2023		 (Dec 31 2022)
2022		 (Dec 31 2021)
2021
Total Investments in Millions 88 150 256 199 286
Y / Y Investment Growth -41.07 % -41.42 % 28.69 % -30.47 % 34.63 %
Net Income in Millions -99 -127 -122 -115 -112
Y / Y Net Income Growth - - - - -
Annual Return On Investment -112.65 % -84.85 % -47.62 % -58.07 % -39.07 %


Annual Roi Comment


Definition and Formula of Return on Investment

Other ROI Ratios
Major Pharmaceutical Preparations Industry Roi Trends and Statistics
Healthcare Sector Return On Investment Statistics
Roi Trends for overall market
PRLD's Roi Ratio versus Major Pharmaceutical Preparations Industry, Healthcare Sector and total Market
Highest Ranking Return On Investment
Lowest Ranking Return On Investment
Subscribers only: Roi for PRLD's Competitors
Subscribers only: Roi for Prelude Therapeutics Inc's Suppliers
Subscribers only: Return On Investment for PRLD's Customers

Other Ratios
PRLD's Roa PRLD's Inventory Turnover Ratio PRLD's Growth Rates PRLD's Dividend Statistics
PRLD's Profitability Ratios PRLD's Asset Turnover Ratio PRLD's Dividend Growth
PRLD's Roe PRLD's Valuation Ratios PRLD's Financial Strength Ratios PRLD's Dividend Payout Ratio



Companies with similar Return On Investment at Jun 30 2026, within Healthcare Sector ROI

Date modified: 2026-09-05T15:26:42+00:00



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