The company depends on several sole suppliers and contract manufacturing organizations (CMOs) for commercial inventory and clinical supplies of YUTREPIA and related products. LGM Pharma, LLC supplies treprostinil, the active pharmaceutical ingredient in YUTREPIA. Plastiape S.p.A provides the RS00 Model DPI device used to administer YUTREPIA. Lonza Tampa LLC handles encapsulation and packaging services for YUTREPIA. Treprostinil Injection supply is managed by partner Sandoz, which holds the ANDA, manages inventory and sales revenue, and acts as manufacturer or contracted party for the entire supply chain. Chengdu is contracted to supply the RG 3mL Medication Cartridge for use with CADD-MS 3 infusion pumps for Treprostinil Injection administration. ICU Medical manufactures the pumps used for Treprostinil Injection but does not have a contractual relationship with the company. L606 is manufactured exclusively by CMOs using proprietary liposomal formulation methods from Pharmosa, which also supports establishing a redundant global supply chain. The proprietary nebulizer for L606 is manufactured by Vectura Limited. The company holds a License Agreement with Pharmosa for the development and commercialization of L606 and a Device License Agreement for Pharmosa’s next-generation smart-technology nebulizers intended for use with L606.
Liquidia's Comment on Supply Chain
The company depends on several sole suppliers and contract manufacturing organizations (CMOs) for commercial inventory and clinical supplies of YUTREPIA and related products. LGM Pharma, LLC supplies treprostinil, the active pharmaceutical ingredient in YUTREPIA. Plastiape S.p.A provides the RS00 Model DPI device used to administer YUTREPIA. Lonza Tampa LLC handles encapsulation and packaging services for YUTREPIA. Treprostinil Injection supply is managed by partner Sandoz, which holds the ANDA, manages inventory and sales revenue, and acts as manufacturer or contracted party for the entire supply chain. Chengdu is contracted to supply the RG 3mL Medication Cartridge for use with CADD-MS 3 infusion pumps for Treprostinil Injection administration. ICU Medical manufactures the pumps used for Treprostinil Injection but does not have a contractual relationship with the company. L606 is manufactured exclusively by CMOs using proprietary liposomal formulation methods from Pharmosa, which also supports establishing a redundant global supply chain. The proprietary nebulizer for L606 is manufactured by Vectura Limited. The company holds a License Agreement with Pharmosa for the development and commercialization of L606 and a Device License Agreement for Pharmosa’s next-generation smart-technology nebulizers intended for use with L606.
Sources:
Liquidia Corporation's official press releases and regulatory filings; CSIMarket.com's supply-chain research; and the financial filings and press releases of other companies cited in this report.
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