Akebia Therapeutics Inc recorded an increase in cost of sales by 5.09 % year on year, relative to one quarter ago cost of sales fell by -15.18 % in Q2.
Auryxia's active pharmaceutical ingredient, ferric citrate, is synthesized at commercial scale from starting materials sourced from multiple suppliers. The company has established relationships with contract manufacturing organizations (CMOs) to support supply for commercial sales and clinical trials. Currently, the manufacture of Auryxia's drug substance and drug product relies on single-source suppliers. The drug substance is supplied by Siegfried Evionnaz SA under a supply agreement featuring per-kilogram pricing and minimum purchase requirements, though the agreement is not exclusive. The drug product is supplied by Patheon Manufacturing Services LLC (Thermo Fisher) under a Master Manufacturing Service Agreement with tiered per-bottle pricing that decreases as volume increases.
Akebia Therapeutics Inc's Comment on Supply Chain
Auryxia's active pharmaceutical ingredient, ferric citrate, is synthesized at commercial scale from starting materials sourced from multiple suppliers. The company has established relationships with contract manufacturing organizations (CMOs) to support supply for commercial sales and clinical trials. Currently, the manufacture of Auryxia's drug substance and drug product relies on single-source suppliers. The drug substance is supplied by Siegfried Evionnaz SA under a supply agreement featuring per-kilogram pricing and minimum purchase requirements, though the agreement is not exclusive. The drug product is supplied by Patheon Manufacturing Services LLC (Thermo Fisher) under a Master Manufacturing Service Agreement with tiered per-bottle pricing that decreases as volume increases.
Sources:
Akebia Therapeutics Inc 's official press releases and regulatory filings; CSIMarket.com's supply-chain research; and the financial filings and press releases of other companies cited in this report.
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