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2025 Year to Date Stock Market Performance
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2025 Year to Date Stock Market Performance
Scroll for the next column of best performing
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2025 Year to Date Performance of Large Cap Stocks
Here are the best and worst performing Large-Cap Stocks for Year To Date 2025.
The Large-Cap Company is defined with the market capitalization, trading above 5 billion dollars U.S. as of 05/18/25.
Scroll for the next column of worst performing
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| In Alphabetical Order |
Year To Date 2025 |
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2025 Year to Date Stock Market Losers
Scroll for the next column of worst performing
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XFOR
$2.92
$-19.6400 
-87.06%
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X4 Pharmaceuticals Inc
Biotechnology & Pharmaceuticals Industry
X4 Pharmaceuticals Inc stock went down by -49.7 % over the course of the last month, this brings the share price to -56.1% during the Q2 of 2025.
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Biotechnology & Pharmaceuticals Industry
XFOR $2.92
$-19.6400
-87.06%
Year To Date 2025.
X4 Pharmaceuticals Inc stock went down by -49.7 % over the course of the last month, this brings the share price to -56.1% during the Q2 of 2025.
|
| Market Cap. |
Revenues TTM |
| $
20.058 mill. |
$
31.364 mill.
|
| Employees |
Shares Outstanding |
|
43 |
7 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
- % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
14.598 mill. |
24.93 |
WIMI
$4.3
$-29.3000
-87.20%
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Wimi Hologram Cloud Inc
Software & Programming Industry
During the past 5 trading days Wimi Hologram Cloud Inc shares went down by -8.7%, this brings the share price to -78.92% in the past 90 days.
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Software & Programming Industry
WIMI $4.3
$-29.3000
-87.20%
Year To Date 2025.
During the past 5 trading days Wimi Hologram Cloud Inc shares went down by -8.7%, this brings the share price to -78.92% in the past 90 days.
|
| Market Cap. |
Revenues TTM |
| $
750.213 mill. |
$
82.647 mill.
|
| Employees |
Shares Outstanding |
|
65 |
174 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
-15.64 % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-72.058 mill. |
- |
MBIO
$1.12
$-9.3250
-89.28%
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Mustang Bio inc
Major Pharmaceutical Preparations Industry
Wimi Hologram Cloud Inc shares went down by -8.12 % during the trailing 30 days, this brings the share price to -60% in the past 90 days.
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Major Pharmaceutical Preparations Industry
MBIO $1.12
$-9.3250
-89.28%
Year To Date 2025.
Wimi Hologram Cloud Inc shares went down by -8.12 % during the trailing 30 days, this brings the share price to -60% in the past 90 days.
|
| Market Cap. |
Revenues TTM |
| $
0.183 mill. |
$
- mill.
|
| Employees |
Shares Outstanding |
|
32 |
0 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
- % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-70.209 mill. |
- |
PLRX
$1.38
$-11.9000
-89.61%
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Pliant Therapeutics Inc
Major Pharmaceutical Preparations Industry
Pliant Therapeutics Inc shares dropped -90.96% from a year ago, this brings the year to date performance to -89.61%.
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Major Pharmaceutical Preparations Industry
PLRX $1.38
$-11.9000
-89.61%
Year To Date 2025.
Pliant Therapeutics Inc shares dropped -90.96% from a year ago, this brings the year to date performance to -89.61%.
|
| Market Cap. |
Revenues TTM |
| $
84.487 mill. |
$
- mill.
|
| Employees |
Shares Outstanding |
|
26 |
61 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
- % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-219.515 mill. |
- |
GRI
$1.5
$-12.9500
-89.62%
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Gri Bio Inc
Major Pharmaceutical Preparations Industry
During the past 5 trading days Gri Bio Inc stock dropped by -3.23%, while Gri Bio Inc stock dropped -78.99% from a year before.
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Major Pharmaceutical Preparations Industry
GRI $1.5
$-12.9500
-89.62%
Year To Date 2025.
During the past 5 trading days Gri Bio Inc stock dropped by -3.23%, while Gri Bio Inc stock dropped -78.99% from a year before.
|
| Market Cap. |
Revenues TTM |
| $
0.788 mill. |
$
- mill.
|
| Employees |
Shares Outstanding |
|
- |
1 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
- % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-9.366 mill. |
- |
SVRE
$1.36
$-12.0300
-89.84%
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Saverone 2014 Ltd
Cloud Computing & Data Analytics Industry
Saverone 2014 Ltd stock went down -81.96% from a year ago, while Saverone 2014 Ltd stock went down -81.96% from a year before.
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Cloud Computing & Data Analytics Industry
SVRE $1.36
$-12.0300
-89.84%
Year To Date 2025.
Saverone 2014 Ltd stock went down -81.96% from a year ago, while Saverone 2014 Ltd stock went down -81.96% from a year before.
|
| Market Cap. |
Revenues TTM |
| $
3.283 mill. |
$
2.720 mill.
|
| Employees |
Shares Outstanding |
|
- |
2 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
128.00 % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-33.835 mill. |
- |
VCIG
$3.08
$-30.1200
-90.72%
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Vci Global Limited
Professional Services Industry
Vci Global Limited stock dropped by -31.4 % in May 2025 so far, while Vci Global Limited stock dropped -82.5% from a year before.
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Professional Services Industry
VCIG $3.08
$-30.1200
-90.72%
Year To Date 2025.
Vci Global Limited stock dropped by -31.4 % in May 2025 so far, while Vci Global Limited stock dropped -82.5% from a year before.
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| Market Cap. |
Revenues TTM |
| $
105.990 mill. |
$
8.079 mill.
|
| Employees |
Shares Outstanding |
|
- |
34 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
0.00 % |
MRQ Y/Y
0.00 % |
| Net Income TTM |
P/E |
| $
4.614 mill. |
23.69 |
SMX
$1.37
$-13.5230
-90.80%
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Smx security Matters Public Limited Company
Industrial Machinery and Components Industry
During the past week Smx security Matters Public Limited Company stock declined by -2.84%, this brings the share price to -56.23% in the past 90 days.
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Industrial Machinery and Components Industry
SMX $1.37
$-13.5230
-90.80%
Year To Date 2025.
During the past week Smx security Matters Public Limited Company stock declined by -2.84%, this brings the share price to -56.23% in the past 90 days.
|
| Market Cap. |
Revenues TTM |
| $
104.423 mill. |
$
9.370 mill.
|
| Employees |
Shares Outstanding |
|
30 |
76 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
642.47 % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-20.989 mill. |
- |
ZCAR
$3.425
$-34.3750
-90.94%
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Innovative International Acquisition Corp
Rental & Leasing Industry
Innovative International Acquisition Corp shares dropped -99.29% from a year ago, while Innovative International Acquisition Corp shares dropped -99.29% from a year before.
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Rental & Leasing Industry
ZCAR $3.425
$-34.3750
-90.94%
Year To Date 2025.
Innovative International Acquisition Corp shares dropped -99.29% from a year ago, while Innovative International Acquisition Corp shares dropped -99.29% from a year before.
|
| Market Cap. |
Revenues TTM |
| $
0.381 mill. |
$
9.359 mill.
|
| Employees |
Shares Outstanding |
|
- |
0 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
- % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
0.620 mill. |
- |
GDHG
$5.68
$-58.8200
-91.19%
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Golden Heaven Group Holdings Ltd
Hotels & Tourism Industry
Innovative International Acquisition Corp shares improved by 1.33 % during the preceding 30 days, meanwhile, GDHG stock went up by 3.27% during the past 5 trading days.
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Hotels & Tourism Industry
GDHG $5.68
$-58.8200
-91.19%
Year To Date 2025.
Innovative International Acquisition Corp shares improved by 1.33 % during the preceding 30 days, meanwhile, GDHG stock went up by 3.27% during the past 5 trading days.
|
| Market Cap. |
Revenues TTM |
| $
5.772 mill. |
$
31.787 mill.
|
| Employees |
Shares Outstanding |
|
- |
1 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
0.00 % |
MRQ Y/Y
0.00 % |
| Net Income TTM |
P/E |
| $
6.550 mill. |
0.87 |
CRKN
$1.6525
$-17.8475
-91.53%
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Crown Electrokinetics Corp
IT Infrastructure Industry
Crown Electrokinetics Corp stock went down -99.96% from a year ago, this brings the share price to -64.77% in the past 90 days.
|
IT Infrastructure Industry
CRKN $1.6525
$-17.8475
-91.53%
Year To Date 2025.
Crown Electrokinetics Corp stock went down -99.96% from a year ago, this brings the share price to -64.77% in the past 90 days.
|
| Market Cap. |
Revenues TTM |
| $
2.764 mill. |
$
29.828 mill.
|
| Employees |
Shares Outstanding |
|
12 |
2 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
306.45 % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-39.989 mill. |
- |
RNAZ
$8.16
$-90.6800
-91.74%
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Transcode Therapeutics Inc
Major Pharmaceutical Preparations Industry
Transcode Therapeutics Inc stock dropped -99.23% from a year ago, this brings the year to date performance to -91.74%.
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Major Pharmaceutical Preparations Industry
RNAZ $8.16
$-90.6800
-91.74%
Year To Date 2025.
Transcode Therapeutics Inc stock dropped -99.23% from a year ago, this brings the year to date performance to -91.74%.
|
| Market Cap. |
Revenues TTM |
| $
2.906 mill. |
$
- mill.
|
| Employees |
Shares Outstanding |
|
10 |
0 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
- % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-16.786 mill. |
- |
TNON
$1.11
$-16.0900
-93.55%
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Tenon Medical Inc
Medical Equipment & Supplies Industry
Tenon Medical Inc shares dropped -97.96% from a year ago, this brings the year to date performance to -93.55%.
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Medical Equipment & Supplies Industry
TNON $1.11
$-16.0900
-93.55%
Year To Date 2025.
Tenon Medical Inc shares dropped -97.96% from a year ago, this brings the year to date performance to -93.55%.
|
| Market Cap. |
Revenues TTM |
| $
3.993 mill. |
$
3.284 mill.
|
| Employees |
Shares Outstanding |
|
27 |
4 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
0.97 % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-13.713 mill. |
- |
RSLS
$6.28
$-107.7200
-94.49%
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Reshape Lifesciences Inc
Major Pharmaceutical Preparations Industry
Reshape Lifesciences Inc shares went down by -21.52 % over the past 30 Days, meanwhile, RSLS shares increased by 4.49% during the past 5 trading days.
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Major Pharmaceutical Preparations Industry
RSLS $6.28
$-107.7200
-94.49%
Year To Date 2025.
Reshape Lifesciences Inc shares went down by -21.52 % over the past 30 Days, meanwhile, RSLS shares increased by 4.49% during the past 5 trading days.
|
| Market Cap. |
Revenues TTM |
| $
3.238 mill. |
$
7.057 mill.
|
| Employees |
Shares Outstanding |
|
65 |
1 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
-55.23 % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-7.130 mill. |
- |
AREB
$2.48
$-43.2700
-94.58%
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American Rebel Holdings Inc
Miscellaneous Fabricated Products Industry
American Rebel Holdings Inc shares went down by -18.42 % during May 2025, this brings the share price to -30.14% during the Q2 of 2025.
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Miscellaneous Fabricated Products Industry
AREB $2.48
$-43.2700
-94.58%
Year To Date 2025.
American Rebel Holdings Inc shares went down by -18.42 % during May 2025, this brings the share price to -30.14% during the Q2 of 2025.
|
| Market Cap. |
Revenues TTM |
| $
0.142 mill. |
$
9.356 mill.
|
| Employees |
Shares Outstanding |
|
15 |
0 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
-97.96 % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-19.125 mill. |
- |
CYN
$4.73
$-118.2700
-96.15%
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Cyngn Inc
Cloud Computing & Data Analytics Industry
Cyngn Inc stock declined by -6.71 % over the course of May, this brings the share price to 7.26% during the Q2 of 2025.
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Cloud Computing & Data Analytics Industry
CYN $4.73
$-118.2700
-96.15%
Year To Date 2025.
Cyngn Inc stock declined by -6.71 % over the course of May, this brings the share price to 7.26% during the Q2 of 2025.
|
| Market Cap. |
Revenues TTM |
| $
5.444 mill. |
$
0.390 mill.
|
| Employees |
Shares Outstanding |
|
14 |
1 mill. |
| Revenue Growth |
Income Growth |
| MRQ Y/Y
87.04 % |
MRQ Y/Y
- % |
| Net Income TTM |
P/E |
| $
-31.374 mill. |
- |
|
8,053.53 %
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